Atorvastatin, a chemical ([R-(R*, R*)]-2-(4-fluorophenyl)-b,ddihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]1 H-pyrole-1-heptanoic acid), is a synthetic HMG-Co A (3-hydroxy-3-methylglutaryl-coenzyme A)r...Atorvastatin, a chemical ([R-(R*, R*)]-2-(4-fluorophenyl)-b,ddihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]1 H-pyrole-1-heptanoic acid), is a synthetic HMG-Co A (3-hydroxy-3-methylglutaryl-coenzyme A)reductase inhibitor. It has been shown to be remarkably efficacious in decreasing the level of cholesterol and triglyceride(1)In order to quantify the level of atorvastatin in plasma, it needs a sensitive, rapid and selective method.展开更多
文摘Atorvastatin, a chemical ([R-(R*, R*)]-2-(4-fluorophenyl)-b,ddihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]1 H-pyrole-1-heptanoic acid), is a synthetic HMG-Co A (3-hydroxy-3-methylglutaryl-coenzyme A)reductase inhibitor. It has been shown to be remarkably efficacious in decreasing the level of cholesterol and triglyceride(1)In order to quantify the level of atorvastatin in plasma, it needs a sensitive, rapid and selective method.
