Macro-and Micro-physical Characteristics of Different Parts of Mixed Convective-stratiform Clouds and Differences in Their Responses to Seeding

This study investigates the cloud macro-and micro-physical characteristics in the convective and stratiform regions and their different responses to the seeding for mixed convective-stratiform clouds that occurred in Shandong province on 21 May 2018,based on the observations from the aircraft,the Suomi National Polar-Orbiting Partnership(NPP)satellite,and the high-resolution Himawari-8(H8)satellite.The aircraft observations show that convection was deeper and radar echoes were significantly enhanced with higher tops in response to seeding in the convective region.This is linked with the conversion of supercooled liquid droplets to ice crystals with released latent heat,resulting in strengthened updrafts,enhanced radar echoes,higher cloud tops,and more and larger precipitation particles.In contrast,in the stratiform cloud region,after the Silver Iodide(AgI)seeding,the radar echoes become significantly weaker at heights close to the seeding layer,with the echo tops lowered by 1.4–1.7 km.In addition,a hollow structure appears at the height of 6.2–7.8 km with a depth of about 1.6 km and a diameter of about 5.5 km,and features such as icing seeding tracks appear.These suggest that the transformation between droplets and ice particles was accelerated by the seeding in the stratiform part.The NPP and H8 satellites also show that convective activity was stronger in the convective region after seeding;while in the stratiform region,a cloud seeding track with a width of 1–3 km appears 10 km downstream of the seeding layer 15 minutes after the AgI seeding,which moves along the wind direction as width increases.

Plant Stem Cell Informatics Database(PSCIdb):A comprehensive computational platform for identifying and analyzing genes related to plant stem cells

Dear Editor,Stem cells in the meristems of land plants share conserved functions,remaining undifferentiated while continually dividing and producing daughter cells that eventually differentiate into various new organs(Meyerowitz,1997;Heidstra and Sabatini,2014).Stem cell activity is therefore essential for sustaining plant growth and development,determining yield and biomass production,and dictating the diversity of body formation and plant architecture across species(Meyerowitz,1997;Heidstra and Sabatini,2014;Harrison,2017;Kitagawa and Jackson,2019).

Operational Plan,Effect Verification,and Key Technical Settings for a Stadium-Scale Artificial Rain Reduction Experiment

To explore the key technologies of artificial weather modification for specific targets(e.g.,a stadium)and improve the efficiency of artificial rainfall modification for major events,this study conducts an artificial rainfall reduction experiment for the closing ceremony of Nanjing Youth Olympic Games on 28 August 2014.Satellite retrievals,radar observations,sounding data,and other sources of information as well as Cloud and Precipitation Accurate Analysis System(CPAS)are used in this study.The main conclusions are as follows.(1)On 28 August 2014,a large-scale cumulus cloud system with mixed-phase stratocumulus and stratus precipitation was observed.This system was influenced by the weak shear of a low-level trough and the precipitation was dominated by cold clouds with dry layers between clouds.Thereby,we adopted the crystal-priming over-catalytic hypothesis and conducted a rocket-catalytic rain abatement operation at a certain distance(100–25 km)from the stadium.Rocket shootings of different intensities were implemented for two echoes that affected the stadium successively(two rounds of 15 rocket shootings within15 min for an isolated weak echo IA;multiple rounds of 156 rocket shootings within 80 min for a strong echo IB).Amazingly,after the shootings with the catalysis in the air,reflectivity of the two echoes was reduced at all altitudes with the most significant reduction at the 2-km altitude,and the time needed for the obvious reduction was 40 min.The most obvious reduction of the two echoes then maintained for 60 and 53 min,respectively,and the operation time needed for the echo zone to recover after the stop of rocket shooting was 108 min for echo IA and 90 min for echo IB.The two echoes moving across the stadium during the time period of the closing ceremony(2000–2130 local time)were at their minimal strengths,with almost no echo over the target stadium.This demonstrates that the rocket shooting strategy of over-crystallization catalysis is effective,and the shooting site,time,and dose are reasonable.The following technical parameters were used during this experiment.At about 80–25 km away from the target stadium in the west,the rocket shooting lasted for 15–80 min and the doses were not less than 1 shot min~(-1)(1 shot min~(-1)for echo IA,2.25 shots min~(-1)for echo IB).The attenuation rate was 0.21 dBZ min~(-1)for the average 15 dBZ of echo IA.For the average 25 dBZ of echo IB,the attenuation rate was 0.27 dBZ min~(-1).The above technical settings helped achieve the goal of reducing rain over the stadium to almost zero for nearly 1-h period during the critical time of the event.

贵州省典型汞铊矿区周边农田土壤跳虫群落特征

大量的采矿活动导致矿区周边土壤重金属污染,严重危害土壤生物安全。汞、铊等重金属元素毒性强,相关污染的土壤生态风险鲜有研究。跳虫作为土壤环境变化指示生物,能很好地反映土壤质量的健康状况。本研究以贵州省某汞铊矿区周边的农田土壤为研究对象,按离矿区距离和作物类型设置4个采样区,每个采样区种植2种作物,每种作物农田设置3个样方。研究土壤跳虫群落结构和多样性及其影响因子。结果表明,调查区内跳虫平均密度为12,000 ind./m2;采样区距离矿区越近,土壤重金属污染程度越大,综合污染指数越高,跳虫种数、密度、多样性和丰富度指数均呈先增加再降低的趋势;环境因子分析表明重金属显著影响跳虫群落结构:Folsomides americanus、Isotomiella minor和Protaphorura encarpatus数量与汞、铊和砷含量呈负相关。高有机质含量能缓解重金属对土壤跳虫的影响,但作物类型(玉米与薏仁)对土壤跳虫群落结构的影响无显著差异。本研究结果表明土壤有机质或能反向调节重金属污染对土壤跳虫群落的影响。

Identifying Supercooled Liquid Water in Cloud Based on Airborne Observations: Correlation of Cloud Particle Number Concentration with Icing Probability and Proportion of Spherical Particles

Identifying supercooled liquid water(SLW)in clouds is critical for weather modification,aviation safety,and atmospheric radiation calculations.Currently,aircraft identification in the SLW area mostly depends on emprical estimation of cloud particle number concentration(N_(c))in China,and scientific verification and quantitative identification criteria are urgently needed.In this study,the observations are from the Fast Cloud Droplets Probe,Rosemount ice detector(RICE),and Cloud Particle Imager(CP_(i))onboard a King Air aircraft during seven flights in 2018 and 2019 over central and eastern China.Based on this,the correlation among N_(c),the proportion of spherical particles(P_(s)),and the probability of icing(P_(i))in supercooled stratiform and cumulus-stratus clouds is statistically analyzed.Subsequently,this study proposes a method to identify SLW areas using N_(c) in combination with ambient temperature.The reliability of this method is evaluated through the true skill statistics(TSS)and threat score(TS)methods.Numerous airborne observations during the seven flights reveal a strong correlation among Nc,P_(s),and P_(i)at the temperature from 0 to−18°C.When Nc is greater than a certain threshold of 5 cm^(−3),there is always the SLW,i.e.,P_(i)and P_(s)are high.Evaluation results demonstrate that the TSS and TS values for Nc=5 cm^(−3)are higher than those for Nc<5 cm^(−3),and a larger Nc threshold(>5 cm^(−3))corresponds to a higher SLW identification hit rate and a higher SLW content.Therefore,Nc=5 cm^(−3)can be used as the minimum criterion for identifying the SLW in clouds at temperature lower than 0°C.The SLW identification method proposed in this study is especially helpful in common situations where aircraft are equipped with only Nc probes and without the CP_(i)and RICE.

Harnessing natural killer cells to develop next-generation cellular immunotherapy

Cellular immunotherapy harnesses the body’’s own immune system to fight cancer by using engineered T cells,macrophages,or natural killer(NK)cells.Compared to chimeric antigen receptor T(CAR-T)cells that are commonly used to treat hematological malignancies,CAR-NK cells have shown remarkable therapeutic effectiveness while exhibiting enhanced safety,reduced risk of graft-versus-host disease,fewer side effects,and amplified antitumor efficacy.Preclinical trials have unveiled the high potential of adoptive CAR-NK cell therapy to curtail or even eliminate both hematological malignancies and solid tumors in animal models.We brought forth herein the design principle of CAR-NK cells,highlighted the latest progress in the preclinical testing and clinical trials of CAR-NK cells,briefly delved into discussed major roadblocks in CAR-NK therapy,and discussed potential solutions to surmount these challenges.Given the accelerated progress in both basic and translational studies on immune cell engineering,CAR-NK cell therapy promises to become a serious contender and important addition to the next-generation cell-based immunotherapy.