Background: There is a need for a standardized clinical grading system for a more objective and accurate assessment of the severity of hand eczema (HE). Objectives: To develop and validate a scoring system called the ...Background: There is a need for a standardized clinical grading system for a more objective and accurate assessment of the severity of hand eczema (HE). Objectives: To develop and validate a scoring system called the hand eczema severity index (HECSI) designed for clinical assessment of HE.Methods: Twelve dermatologists (observers) assessed 15 HE patients twice, with an interval of 30 min. The study was performed blinded for the observers, and only the hands and wrists of the patients were visible to the observers. Agreement between the observers was determined by using the intraclass correlation coefficient (ICC), which is the correlation between (single) ratings of the same patient. Results: ICC for total HECSI score was 0.79 at the first assessment and 0.84 at the second assessment, ICC for intraobserver agreement was 0.90. Conclusions: Overall excellent agreement existed for both inter-and intra-observer reliability and the scoring system is suggested for use in future clinical studies on HE. Because HECSI is an entirely objective assessment of clinical signs, in addition, inclusion of patient-rated symptoms should be considered.展开更多
Occupational hand eczema(OHE) is the most frequently recognized work-related disease in Denmark and the annual cost to society is high. Understanding of the epidemiology of OHE is essential to be able to give appropri...Occupational hand eczema(OHE) is the most frequently recognized work-related disease in Denmark and the annual cost to society is high. Understanding of the epidemiology of OHE is essential to be able to give appropriate recommendations for its prevention. The study comprised 758 persons, 490 females and 268 males with recognized OHE in the period October 2001 to November 2002. Data were obtained prospectively from the National Board of Industrial Industry Registry and from a self-administered questionnaire(response rate, 82%). The most frequently recognized diagnosis was irritant contact dermatitis(ICD), mainly caused by wet occupations. The proportion of occupational ICD was equal for males and females, 59.7%and 63.1%, respectively. The estimated rates of OHE were high for bakers, hairdressers and dental surgery assistants, and a high proportion of apprentices were found among hairdressers. The prevalence of atopic dermatitis was low(16.4%) compared to previous studies among hand eczema patients. The prevalence of occupational allergic contact dermatitis in the study populationwassubstantiallyhigheramongmalesthanfemales,andthe most frequent causes among males were allergy to chromium (leather exposure), rubber additives(gloves) and nickel due to exposure from work tools and metalworking industry.展开更多
文摘Background: There is a need for a standardized clinical grading system for a more objective and accurate assessment of the severity of hand eczema (HE). Objectives: To develop and validate a scoring system called the hand eczema severity index (HECSI) designed for clinical assessment of HE.Methods: Twelve dermatologists (observers) assessed 15 HE patients twice, with an interval of 30 min. The study was performed blinded for the observers, and only the hands and wrists of the patients were visible to the observers. Agreement between the observers was determined by using the intraclass correlation coefficient (ICC), which is the correlation between (single) ratings of the same patient. Results: ICC for total HECSI score was 0.79 at the first assessment and 0.84 at the second assessment, ICC for intraobserver agreement was 0.90. Conclusions: Overall excellent agreement existed for both inter-and intra-observer reliability and the scoring system is suggested for use in future clinical studies on HE. Because HECSI is an entirely objective assessment of clinical signs, in addition, inclusion of patient-rated symptoms should be considered.
文摘Occupational hand eczema(OHE) is the most frequently recognized work-related disease in Denmark and the annual cost to society is high. Understanding of the epidemiology of OHE is essential to be able to give appropriate recommendations for its prevention. The study comprised 758 persons, 490 females and 268 males with recognized OHE in the period October 2001 to November 2002. Data were obtained prospectively from the National Board of Industrial Industry Registry and from a self-administered questionnaire(response rate, 82%). The most frequently recognized diagnosis was irritant contact dermatitis(ICD), mainly caused by wet occupations. The proportion of occupational ICD was equal for males and females, 59.7%and 63.1%, respectively. The estimated rates of OHE were high for bakers, hairdressers and dental surgery assistants, and a high proportion of apprentices were found among hairdressers. The prevalence of atopic dermatitis was low(16.4%) compared to previous studies among hand eczema patients. The prevalence of occupational allergic contact dermatitis in the study populationwassubstantiallyhigheramongmalesthanfemales,andthe most frequent causes among males were allergy to chromium (leather exposure), rubber additives(gloves) and nickel due to exposure from work tools and metalworking industry.
