Clear cell renal cell carcinoma(ccRCC)is the most common subtype of renal cell carcinoma,accounting for approximately 80%of cases.Although most patients in the early stages of ccRCC can be cured by surgery,ccRCC is of...Clear cell renal cell carcinoma(ccRCC)is the most common subtype of renal cell carcinoma,accounting for approximately 80%of cases.Although most patients in the early stages of ccRCC can be cured by surgery,ccRCC is often in the advanced stage when patients are diagnosed,.with:>30%of the patients presenting with distant metastases at the time of diagnosis.For ccRCC patients with distant metastases,the 5-year survival is only 12%.Immunotherapy selectively corrects tumor microenviron-ment(TME)immunity,which is of great significance for patients with advanced ccRCC.展开更多
基金funded by the General Project of China’s National Natural Science Foundation(No.81872086)。
文摘Clear cell renal cell carcinoma(ccRCC)is the most common subtype of renal cell carcinoma,accounting for approximately 80%of cases.Although most patients in the early stages of ccRCC can be cured by surgery,ccRCC is often in the advanced stage when patients are diagnosed,.with:>30%of the patients presenting with distant metastases at the time of diagnosis.For ccRCC patients with distant metastases,the 5-year survival is only 12%.Immunotherapy selectively corrects tumor microenviron-ment(TME)immunity,which is of great significance for patients with advanced ccRCC.
