A highly chemoselective method for the synthesis of heterocyclic [3.3.3]propellane derivatives was developed via sequential three-component reactions of acenaphthenequinone, malononitrile/cyanoacetate and a variety of...A highly chemoselective method for the synthesis of heterocyclic [3.3.3]propellane derivatives was developed via sequential three-component reactions of acenaphthenequinone, malononitrile/cyanoacetate and a variety of 1,3-dicarbonyl compounds under mild conditions in ethanol. A plausible mechanism for this type of reaction was proposed. The value of this method was highlighted by its high selectivity, simple procedures, and good yields.展开更多
文摘A highly chemoselective method for the synthesis of heterocyclic [3.3.3]propellane derivatives was developed via sequential three-component reactions of acenaphthenequinone, malononitrile/cyanoacetate and a variety of 1,3-dicarbonyl compounds under mild conditions in ethanol. A plausible mechanism for this type of reaction was proposed. The value of this method was highlighted by its high selectivity, simple procedures, and good yields.
