Human toxoplasmosis is caused by the intracellular protozoan parasite Toxoplasma gondii. Although T. gondii infection is generally asymptomatic for most of the immunocompetent adults, severe complications may occur pa...Human toxoplasmosis is caused by the intracellular protozoan parasite Toxoplasma gondii. Although T. gondii infection is generally asymptomatic for most of the immunocompetent adults, severe complications may occur particularly in pregnant women and immunocompromised individual. Host cell immunity plays a critical role in parasite differentiation and persistence in the host. Therefore, genetic polymorphism in the host immune genes, for instance interferon-γ gene could be linked with possibility of T. gondii infection. The objective of the study was to verify the link between the single nucleotide polymorphisms (SNPs) in the IFN-γ gene of pregnant women and T. gondii infection through correlating with anthropometric and sociodemographic parameters. In this study, ninety-two (N = 92) pregnant women (16 - 40 years) and healthy controls (N = 95) with similar age ranges were included. Among them, 25% (n = 23) pregnant women were seropositive for T. gondii IgG antibodies by Rapid Test Assay. Allelic and genotypic frequencies of IFN-γ +874T/A (rs2430561) SNPs were evaluated by using ARMS-PCR. The distribution of the A and T alleles in the specific position of the IFN-γ gene in the T. gondii-infected pregnant women and the control groups did not differ significantly, according to the data. However, we found a higher frequency (13.04%) of A/A genotype in T. gondii infected pregnant women as compared to non-infected individuals (8.70%), demonstrating that T. gondii infection susceptibility may be increased by homozygosity for the A allele. Further studies are to be needed to find out the link between host gene polymorphism and T. gondii infection in Bangladesh.展开更多
Jamuna River is one of the principal rivers of Bangladesh, changing continuously due to erosion and accretion over the past decades. This analysis evaluates the East Bank and the West Bank erosion and accretion betwee...Jamuna River is one of the principal rivers of Bangladesh, changing continuously due to erosion and accretion over the past decades. This analysis evaluates the East Bank and the West Bank erosion and accretion between 1996 and 2015 for Jamuna River. An unsupervised classification algorithm and post-classification change employing skills in Geographic Information System are performed to evaluate spatial and temporal dynamics of erosion and accretion for different points of Jamuna River using Bangladesh. Landsat image (1995, 2005, 2015). The correctness of the Landsat-produced map ranges from 82% to 84%. It has been evidently observed that changes in the proportion of erosion and accretion differ in different points of Jamuna River. The highest eroded area is 3.82 square kilometers (km2) during the period of 1995 to 2005 and the highest accreted area is 6.15 square kilometers (km2) during the period of 1995 to 2015. The erosion and accretion values fluctuated from place to place. The changing trend of Riverbank is creating many socio-economic problems in the proximate areas.展开更多
文摘Human toxoplasmosis is caused by the intracellular protozoan parasite Toxoplasma gondii. Although T. gondii infection is generally asymptomatic for most of the immunocompetent adults, severe complications may occur particularly in pregnant women and immunocompromised individual. Host cell immunity plays a critical role in parasite differentiation and persistence in the host. Therefore, genetic polymorphism in the host immune genes, for instance interferon-γ gene could be linked with possibility of T. gondii infection. The objective of the study was to verify the link between the single nucleotide polymorphisms (SNPs) in the IFN-γ gene of pregnant women and T. gondii infection through correlating with anthropometric and sociodemographic parameters. In this study, ninety-two (N = 92) pregnant women (16 - 40 years) and healthy controls (N = 95) with similar age ranges were included. Among them, 25% (n = 23) pregnant women were seropositive for T. gondii IgG antibodies by Rapid Test Assay. Allelic and genotypic frequencies of IFN-γ +874T/A (rs2430561) SNPs were evaluated by using ARMS-PCR. The distribution of the A and T alleles in the specific position of the IFN-γ gene in the T. gondii-infected pregnant women and the control groups did not differ significantly, according to the data. However, we found a higher frequency (13.04%) of A/A genotype in T. gondii infected pregnant women as compared to non-infected individuals (8.70%), demonstrating that T. gondii infection susceptibility may be increased by homozygosity for the A allele. Further studies are to be needed to find out the link between host gene polymorphism and T. gondii infection in Bangladesh.
文摘Jamuna River is one of the principal rivers of Bangladesh, changing continuously due to erosion and accretion over the past decades. This analysis evaluates the East Bank and the West Bank erosion and accretion between 1996 and 2015 for Jamuna River. An unsupervised classification algorithm and post-classification change employing skills in Geographic Information System are performed to evaluate spatial and temporal dynamics of erosion and accretion for different points of Jamuna River using Bangladesh. Landsat image (1995, 2005, 2015). The correctness of the Landsat-produced map ranges from 82% to 84%. It has been evidently observed that changes in the proportion of erosion and accretion differ in different points of Jamuna River. The highest eroded area is 3.82 square kilometers (km2) during the period of 1995 to 2005 and the highest accreted area is 6.15 square kilometers (km2) during the period of 1995 to 2015. The erosion and accretion values fluctuated from place to place. The changing trend of Riverbank is creating many socio-economic problems in the proximate areas.
