Photoheating in a venous blood vessel under near-infrared laser irradiation by a scanning laser beam,which is synchronized with the blood flow velocity,is analyzed numerically by considering the light scattering,absor...Photoheating in a venous blood vessel under near-infrared laser irradiation by a scanning laser beam,which is synchronized with the blood flow velocity,is analyzed numerically by considering the light scattering,absorption,and heat transfer in the blood and surrounding tissues.The scanning regime of the laser irradiation with a wavelength of 1064 nm is found to increase strongly the photoheating of the blood while minimizing the overheating of the skin and the tissues surrounding the blood vessel.Simulations show that the photoheating effect can be additionally enhanced by light-absorbing nanoparticles in the blood.The proposed approach of dynamic laser photohyperthermia with the scanning laser beam is discussed for potential applications in laser phototherapy.展开更多
文摘Photoheating in a venous blood vessel under near-infrared laser irradiation by a scanning laser beam,which is synchronized with the blood flow velocity,is analyzed numerically by considering the light scattering,absorption,and heat transfer in the blood and surrounding tissues.The scanning regime of the laser irradiation with a wavelength of 1064 nm is found to increase strongly the photoheating of the blood while minimizing the overheating of the skin and the tissues surrounding the blood vessel.Simulations show that the photoheating effect can be additionally enhanced by light-absorbing nanoparticles in the blood.The proposed approach of dynamic laser photohyperthermia with the scanning laser beam is discussed for potential applications in laser phototherapy.
