AIM:To investigate the antioxidant activity and total phenolic content from the crude extracts and crude fractions of ten species of Phellinus mushrooms collected from northeast Thailand.METHODS:The samples were teste...AIM:To investigate the antioxidant activity and total phenolic content from the crude extracts and crude fractions of ten species of Phellinus mushrooms collected from northeast Thailand.METHODS:The samples were tested for their radical scavenging activity toward 2,2-diphenyl-1-pricylhydrazyl (DPPH) radical (DPPH method) and total phenolic content (Folin-Ciocalteu method).RESULTS:Some of the investigated extracts exhibited potent radical scavenging activity with the IC 50 ranging from (7.30±0.34) to (19.80±0.13) μg·mL-1.IC 50 were in the range of the standard antioxidant used;quercetin,ascorbic acid and butylated hydroxytoluene (BHT).The strongest scavenging activity as comparable to quercetin was found in the crude 80% EtOH extract of P.torulosus.The crude EtOAc fraction of P.pini showed the highest total phenolic content with a value of 87.76±1.00 equivalent gallic acid (EGA) while the samples with potent antioxidant activity were also determined to have high amount of total phenolics (78.34±0.27 to 51.01±0.38) EGA.CONCLUSION:These results indicated that crude extracts from Phellinus mushrooms have a potential to be natural antioxidant source.展开更多
AIM:To investigate the constituents from the dichloromethane fraction of the mushroom Phellinus lintues.METHODS:Silica gel and Sephadex LH-20 column chromatography were used for the isolation and purification.The stru...AIM:To investigate the constituents from the dichloromethane fraction of the mushroom Phellinus lintues.METHODS:Silica gel and Sephadex LH-20 column chromatography were used for the isolation and purification.The structures of isolated compounds were elucidated based on NMR spectroscopic analyses and mass spectrometric data.RESULTS:Two indole derivatives,7-methoxyindole-3-carboxylic acid methyl ester(1)and 1-methylindole-3-carboxaldehyde(2),and a phenolic compound,(E)-4-(3,4-dihydroxyphenyl)but-3-en-2-one(3)were isolated.CONCLUSION:Compounds 1 and 2 were isolated for the first time from P.linteus.展开更多
基金supported by Center of Excellence for Innovation in Chemistry (PERCH-CIC) and Faculty of Science,Mahasarakham University
文摘AIM:To investigate the antioxidant activity and total phenolic content from the crude extracts and crude fractions of ten species of Phellinus mushrooms collected from northeast Thailand.METHODS:The samples were tested for their radical scavenging activity toward 2,2-diphenyl-1-pricylhydrazyl (DPPH) radical (DPPH method) and total phenolic content (Folin-Ciocalteu method).RESULTS:Some of the investigated extracts exhibited potent radical scavenging activity with the IC 50 ranging from (7.30±0.34) to (19.80±0.13) μg·mL-1.IC 50 were in the range of the standard antioxidant used;quercetin,ascorbic acid and butylated hydroxytoluene (BHT).The strongest scavenging activity as comparable to quercetin was found in the crude 80% EtOH extract of P.torulosus.The crude EtOAc fraction of P.pini showed the highest total phenolic content with a value of 87.76±1.00 equivalent gallic acid (EGA) while the samples with potent antioxidant activity were also determined to have high amount of total phenolics (78.34±0.27 to 51.01±0.38) EGA.CONCLUSION:These results indicated that crude extracts from Phellinus mushrooms have a potential to be natural antioxidant source.
基金supported by Center of Excellence for Innovation in Chemistry (PERCH-CIC) and Faculty of Science,Mahasarakham University
文摘AIM:To investigate the constituents from the dichloromethane fraction of the mushroom Phellinus lintues.METHODS:Silica gel and Sephadex LH-20 column chromatography were used for the isolation and purification.The structures of isolated compounds were elucidated based on NMR spectroscopic analyses and mass spectrometric data.RESULTS:Two indole derivatives,7-methoxyindole-3-carboxylic acid methyl ester(1)and 1-methylindole-3-carboxaldehyde(2),and a phenolic compound,(E)-4-(3,4-dihydroxyphenyl)but-3-en-2-one(3)were isolated.CONCLUSION:Compounds 1 and 2 were isolated for the first time from P.linteus.