In a further aging society,excellent eyesight is an integral part of overall well-being and quality of life.Preserving good vision is crucial to maintaining mobility,independence,and mental health.There can be several...In a further aging society,excellent eyesight is an integral part of overall well-being and quality of life.Preserving good vision is crucial to maintaining mobility,independence,and mental health.There can be several reasons for visual impairment in elderly people,these include age-related macular degeneration,the leading cause of vision loss among older adults,cataract,glaucoma,diabetic retinopathy,retinal detachment,and others.展开更多
The overproduction of reactive oxygen species is defined as oxidative stress.While deprived oxygen supply in tissues is known as hypoxia.These mechanisms contribute to the pathogenesis of several retinal diseases,like...The overproduction of reactive oxygen species is defined as oxidative stress.While deprived oxygen supply in tissues is known as hypoxia.These mechanisms contribute to the pathogenesis of several retinal diseases,like glaucoma,age-related macular degeneration(AMD),and retinal ischemia.Glaucoma is a neurodegenerative disease defined by a progressive loss of retinal ganglion cells(RGCs)and their axons causing visual field defects,which ultimately leads to blindness.While AMD pathogenesis is further characterized by soft drusen,it involves the retinal pigment epithelium and the Bruch’s membrane-choroid complex.展开更多
Glaucoma is currently the second leading cause of blindness worldwide.Due to aging societies the number of patients suffering from this disease will further increase in the next years.Unfortunately,glaucoma can remain...Glaucoma is currently the second leading cause of blindness worldwide.Due to aging societies the number of patients suffering from this disease will further increase in the next years.Unfortunately,glaucoma can remain asymptomatic until it is rather far progressed,hence about 10–50% of patients are unaware they suffer from this disease.Glaucoma is a progressive optic neuropathy associated with changes at the optic nerve head.展开更多
基金supported by FoRUM(Ruhr-University Bochum,Germany,to SCJ)the Deutsche Forschungsgemeinschaft(DFG,Germany,RE-4543/1-1,to SR).
文摘In a further aging society,excellent eyesight is an integral part of overall well-being and quality of life.Preserving good vision is crucial to maintaining mobility,independence,and mental health.There can be several reasons for visual impairment in elderly people,these include age-related macular degeneration,the leading cause of vision loss among older adults,cataract,glaucoma,diabetic retinopathy,retinal detachment,and others.
文摘The overproduction of reactive oxygen species is defined as oxidative stress.While deprived oxygen supply in tissues is known as hypoxia.These mechanisms contribute to the pathogenesis of several retinal diseases,like glaucoma,age-related macular degeneration(AMD),and retinal ischemia.Glaucoma is a neurodegenerative disease defined by a progressive loss of retinal ganglion cells(RGCs)and their axons causing visual field defects,which ultimately leads to blindness.While AMD pathogenesis is further characterized by soft drusen,it involves the retinal pigment epithelium and the Bruch’s membrane-choroid complex.
文摘Glaucoma is currently the second leading cause of blindness worldwide.Due to aging societies the number of patients suffering from this disease will further increase in the next years.Unfortunately,glaucoma can remain asymptomatic until it is rather far progressed,hence about 10–50% of patients are unaware they suffer from this disease.Glaucoma is a progressive optic neuropathy associated with changes at the optic nerve head.
