The ability of epithelial cells to undergo phenotypic transitions during embryo-genesis, wound healing and malignant pro- gression is now widely accepted as a core biological process termed epithelialmesenchymal trans...The ability of epithelial cells to undergo phenotypic transitions during embryo-genesis, wound healing and malignant pro- gression is now widely accepted as a core biological process termed epithelialmesenchymal transition （EMT）. During cancer progression, the process of EMT has been associated with the acquisition of stemness properties, treatment resistance and metastatic progression, hallmarks of malig- nancy.展开更多
文摘The ability of epithelial cells to undergo phenotypic transitions during embryo-genesis, wound healing and malignant pro- gression is now widely accepted as a core biological process termed epithelialmesenchymal transition （EMT）. During cancer progression, the process of EMT has been associated with the acquisition of stemness properties, treatment resistance and metastatic progression, hallmarks of malig- nancy.
