Consciousness is a prismatic and ambiguous concept that still eludes any universal definition. Severe acquired brain injuries resulting in a disorder of con-sciousness(DOC) provide a model from which insights into con...Consciousness is a prismatic and ambiguous concept that still eludes any universal definition. Severe acquired brain injuries resulting in a disorder of con-sciousness(DOC) provide a model from which insights into consciousness can be drawn. A number of recent studies highlight the difficulty in making a diagnosis in patients with DOC based only on behavioral assessments. Here we aim to provide an overview of how neuroimaging techniques can help assess patients with DOC. Such techniques are expected to facilitate a more accurate understanding of brain function in states of unconsciousness and to improve the evaluation of thepatient's cognitive abilities by providing both diagnostic and prognostic indicators.展开更多
近年来,严重脑损伤的死亡率随着急救技术的不断发展显著下降,而继发意识障碍(disorders of consciousness,DOC)患者数量却急剧增加。文章介绍了杭州师范大学国际植物状态和意识科学研究所主办的意识障碍精准评估及临床应用论坛关于意识...近年来,严重脑损伤的死亡率随着急救技术的不断发展显著下降,而继发意识障碍(disorders of consciousness,DOC)患者数量却急剧增加。文章介绍了杭州师范大学国际植物状态和意识科学研究所主办的意识障碍精准评估及临床应用论坛关于意识障碍的分类诊断、治疗干预、新技术手段与未来挑战等报告内容,探讨了国际化视角下多中心、跨学科模式为我国意识障碍领域的科学研究及临床应用带来的启示。展开更多
目的使用昏迷疼痛量表-修订版(nociception coma scale-revised,NCS-R)评估意识障碍患者的疼痛,并分析其信效度,评价该量表在国内的临床应用价值。方法用NCS-R量表对62名意识障碍患者进行疼痛评估,分析量表的内部一致性,评估者间的一致...目的使用昏迷疼痛量表-修订版(nociception coma scale-revised,NCS-R)评估意识障碍患者的疼痛,并分析其信效度,评价该量表在国内的临床应用价值。方法用NCS-R量表对62名意识障碍患者进行疼痛评估,分析量表的内部一致性,评估者间的一致性,评估与再评估的一致性,同时效度。结果该量表的内部一致性Cronbach'α系数为0.611,重复评估总分Sperman相关系数为0.884,运动、言语和面部表情分量表的Cronbach'skappa系数分别为0.856,0.870,0.856,评估者之间的总分Sperman相关系数为0.662,运动、言语和面部表情分量表信度的Cronbach'skappa系数分别为0.962,0.867,0.671;与其他疼痛量表的同时效度的Sperman相关系数为0.560(均P<0.01)。结论NCS-R具有较好的信度和效度,适用于临床医生和研究人员评估意识障碍患者的疼痛情况。展开更多
基金Supported by The European Commissionthe James McDon-nell Foundation+5 种基金the European Space AgencyMind Science Foundationthe French Speaking Community Concerted Research Actionthe Belgian interuniversity attraction polethe Public Utility Foundation"Université Européenne du Travail""Fondazione Europea di Ricerca Biomedica"and the University and University Hospital of Liège
文摘Consciousness is a prismatic and ambiguous concept that still eludes any universal definition. Severe acquired brain injuries resulting in a disorder of con-sciousness(DOC) provide a model from which insights into consciousness can be drawn. A number of recent studies highlight the difficulty in making a diagnosis in patients with DOC based only on behavioral assessments. Here we aim to provide an overview of how neuroimaging techniques can help assess patients with DOC. Such techniques are expected to facilitate a more accurate understanding of brain function in states of unconsciousness and to improve the evaluation of thepatient's cognitive abilities by providing both diagnostic and prognostic indicators.
文摘近年来,严重脑损伤的死亡率随着急救技术的不断发展显著下降,而继发意识障碍(disorders of consciousness,DOC)患者数量却急剧增加。文章介绍了杭州师范大学国际植物状态和意识科学研究所主办的意识障碍精准评估及临床应用论坛关于意识障碍的分类诊断、治疗干预、新技术手段与未来挑战等报告内容,探讨了国际化视角下多中心、跨学科模式为我国意识障碍领域的科学研究及临床应用带来的启示。
文摘目的使用昏迷疼痛量表-修订版(nociception coma scale-revised,NCS-R)评估意识障碍患者的疼痛,并分析其信效度,评价该量表在国内的临床应用价值。方法用NCS-R量表对62名意识障碍患者进行疼痛评估,分析量表的内部一致性,评估者间的一致性,评估与再评估的一致性,同时效度。结果该量表的内部一致性Cronbach'α系数为0.611,重复评估总分Sperman相关系数为0.884,运动、言语和面部表情分量表的Cronbach'skappa系数分别为0.856,0.870,0.856,评估者之间的总分Sperman相关系数为0.662,运动、言语和面部表情分量表信度的Cronbach'skappa系数分别为0.962,0.867,0.671;与其他疼痛量表的同时效度的Sperman相关系数为0.560(均P<0.01)。结论NCS-R具有较好的信度和效度,适用于临床医生和研究人员评估意识障碍患者的疼痛情况。
