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纳米银运载紫杉醇抑制肺癌A549细胞生长的机制研究
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作者 邹建军 苏珊 +4 位作者 曾云云 张贤兰 谢亚琳 苏宁 岑文昌 《广东药科大学学报》 CAS 2019年第4期575-578,共4页
目的将纳米银运载紫杉醇(PTX),以促进PTX进入细胞,评价其对肺癌A549细胞的细胞毒性及作用机制。方法透射电镜(TEM)检测自组装表面功能化纳米银(Ag@PTX)粒径大小,MTT实验检测Ag@PTX对A549细胞的细胞毒性,细胞周期实验和DNA片段化改变用... 目的将纳米银运载紫杉醇(PTX),以促进PTX进入细胞,评价其对肺癌A549细胞的细胞毒性及作用机制。方法透射电镜(TEM)检测自组装表面功能化纳米银(Ag@PTX)粒径大小,MTT实验检测Ag@PTX对A549细胞的细胞毒性,细胞周期实验和DNA片段化改变用于检测A549细胞凋亡。结果透射电镜像结果表明Ag@PTX粒径小(2~2.5 nm)且稳定性好;MTT实验结果发现该纳米系统对A549细胞的细胞毒性高于正常细胞,A549细胞组存活率分别为65%、26%及13%,HK-2细胞存活率分别为97%、95%及94%,对A549细胞生长有选择性抑制作用。细胞周期分析、DNA片段化改变实验证实Ag@PTX抑制A549细胞生长是通过诱导细胞凋亡路径。结论Ag@PTX诱导A549细胞凋亡是抑制其生长的机制之一,Ag@PTX可能成为一种新的化疗药物候选。 展开更多
关键词 纳米银 紫杉醇 肺癌 凋亡
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红阳猕猴桃酵素发酵工艺优化及其体外抗氧化活性 被引量:10
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作者 陈林 苏珊 +2 位作者 吴应梅 徐凤莲 程扬清 《现代食品科技》 CAS 北大核心 2021年第4期224-233,共10页
本实验以红阳猕猴桃为原料,羟基自由基清除率(50%)和感官评价(50%)为综合指标,采用双正交试验优化红阳猕猴桃酵素发酵工艺。首先在酵母(Saccharomyces cerevisiae)、乳酸菌(Lactobacillus bulgaricus和Streptococcus thermophilus)、果... 本实验以红阳猕猴桃为原料,羟基自由基清除率(50%)和感官评价(50%)为综合指标,采用双正交试验优化红阳猕猴桃酵素发酵工艺。首先在酵母(Saccharomyces cerevisiae)、乳酸菌(Lactobacillus bulgaricus和Streptococcus thermophilus)、果胶酶和纤维素酶单因素实验基础上通过正交试验优化添加量,并确定酵母、乳酸菌、果胶酶和纤维素酶添加量分别为2.0%、2.0%、0.5%和2.0%。然后在此基础上进行初始糖添加量、料液比、发酵温度、发酵时间单因素实验并通过正交试验确定红阳猕猴桃酵素最优发酵工艺条件分别为:初始糖添加量20%,料液比1:1.3,36℃持续发酵35 d。最后,在最优发酵条件下制备红阳猕猴桃发酵产品并测定羟基自由基清除率、感官最佳和综合指标分别为94.33%,76.33和85.33。试验表明通过正交试验可以优化红阳猕猴桃酵素发酵工艺以及提高产品品质。抗氧化测定发现优化的红阳猕猴桃发酵产品抗氧化活性明显高于自然发酵(p<0.05),其羟基自由基清除率、DPPH·和ABTS·+自由基清除率分别增加了8.69%、11.89%和36.57%。本研究为推动本地特色红阳猕猴桃深加工产品提供新方法。 展开更多
关键词 红阳猕猴桃酵素 发酵 正交试验 羟基自由基清楚率 感官评价
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EXHIBION TAKES GREAT EMPEROR'S LIFE TO FRANCE
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作者 su san 《China & The World Cultural Exchange》 2003年第4期31-33,共3页
“Court Life of Great Emperor Kang Xi a grand-scale exhibition organized by the Forbidden City Museum, will be held in Versailles, Paris in October 2003. The exhibition will be a highlight of the "China Cultural ... “Court Life of Great Emperor Kang Xi a grand-scale exhibition organized by the Forbidden City Museum, will be held in Versailles, Paris in October 2003. The exhibition will be a highlight of the "China Cultural Year in France”. 展开更多
关键词 “中国文化年” 法国 展览会 康熙皇帝 瓷器 绘画 武器 艺术品 国际影响 文化交流
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Art Gallery in the Urban Village
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作者 su san 《China & The World Cultural Exchange》 2006年第4期20-24,共5页
A quarter of century ago, Shenzhen was just a small township bordering with Hong Kong, with only a tiny population of 30,000, Since the reform and opening up policy was launched in 1979, Shenzhen has been designated a... A quarter of century ago, Shenzhen was just a small township bordering with Hong Kong, with only a tiny population of 30,000, Since the reform and opening up policy was launched in 1979, Shenzhen has been designated as a special economic zone and has seen a startlingly high speed of economic growth. As the fastest-developed, newly-emerged metropolis in the world and probably the largest venue for architectural experiments, Shenzhen has seen its GDP rocketing by 1500 times within a short period of two and half decades. Meanwhile, migrants 14 times as many as original local villagers from across the country, most of which are low-wage factory workers and salesmen, have rushed into the city to pursue their Chinese-style American dreams. Original residents built tensely concentrated garrets on their own lands to cater to the seemingly infinite needs of new comers for dwelling, Thus so-called villages-amidst-the-city, or urban villages, have gradually developed. 展开更多
关键词 深圳市 边界地区 乡镇地区 艺术家 建筑 地方文化 广东
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Chinese Silk Screen Printing Flourishes Nowadays
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作者 su san 《China & The World Cultural Exchange》 2005年第9期20-23,共4页
Silk screen printing is an innovative modern art genre highly relying on technologies and media materials. Although it was only introduced into China twenty years ago, it has quickly stood out of the shadow of wood pr... Silk screen printing is an innovative modern art genre highly relying on technologies and media materials. Although it was only introduced into China twenty years ago, it has quickly stood out of the shadow of wood printing and broken through the confines of materials and tools, developing into an independent style integrating modern art and oriental culture. 展开更多
关键词 中国 丝绸屏风印刷工艺 技术创新 现代艺术 制作材料 工艺美术
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Meet Paris in Yu Xi’s Documentaries
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作者 su san 《China & The World Cultural Exchange》 2004年第3期34-36,共3页
关键词 余熙 摄影家 巴黎 艺术交流 摄影作品
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China Museum of Science and Technology Offers Better Access
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作者 su san 《China & The World Cultural Exchange》 2003年第4期34-36,共3页
Going to temple fairs used to be a major Spring Festival celebration for Beijing natives in the past. But this tradition has changed. Nowadays, it has become a fashion for locals to spend Chinese lunar new year holida... Going to temple fairs used to be a major Spring Festival celebration for Beijing natives in the past. But this tradition has changed. Nowadays, it has become a fashion for locals to spend Chinese lunar new year holidays by visiting science museums. This new sort of Spring Festival pastime is called “temple fairs on science”. 展开更多
关键词 中国科学技术馆 参观者 教育演讲 科学意识 投资
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Chinese Seal:the Beijing 2008 Olympics Emblem
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作者 su san 《China & The World Cultural Exchange》 2003年第6期46-48,共3页
The Beijing 2008 Olympics emblem was finally unveiled. It was shown to th.e public at the sólemn ceremony held at 8:30 p.m. August 3, 2003 in the park of Temple of Heaven, Beijing. When a Chinese statesman and an... The Beijing 2008 Olympics emblem was finally unveiled. It was shown to th.e public at the sólemn ceremony held at 8:30 p.m. August 3, 2003 in the park of Temple of Heaven, Beijing. When a Chinese statesman and an official of the International Olympic Committee(IOC) lifted the yellow wrapping satin, 展开更多
关键词 2008年北京奥运会 中国传统文化 会徽 城市形象 体育事业
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科技创新驱动下的经济发展方式转变分析
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作者 苏珊 《产业科技创新》 2019年第32期55-57,共3页
科技创新是我国经济发展的重要驱动力。要想确保我国在转变经济发展方式过程中取得良好的成果,就需高度重视我国科技创新能力。在此之上,文章简要分析了我国经济发展的现状,并重点论述了科技创新对我国经济发展方式转变的重要作用及其... 科技创新是我国经济发展的重要驱动力。要想确保我国在转变经济发展方式过程中取得良好的成果,就需高度重视我国科技创新能力。在此之上,文章简要分析了我国经济发展的现状,并重点论述了科技创新对我国经济发展方式转变的重要作用及其优化策略,从积极推广自主创新、重点培育科技人才、建立科技创新平台、完善市场竞争制度等方面着手,进而提升我国经济发展水平,使其在科技创新驱动下实现良性发展。 展开更多
关键词 科技创新 经济发展方式 消费诉求 产业结构
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