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Exercise and nutrition benefit skeletal muscle:From influence factor and intervention strategy to molecular mechanism
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作者 Lili Feng Bowen Li +2 位作者 su sean yong Xiaonan Wu Zhenjun Tian 《Sports Medicine and Health Science》 2024年第4期302-314,共13页
Sarcopenia is a progressive systemic skeletal muscle disease induced by various physiological and pathological factors,including aging,malnutrition,denervation,and cardiovascular diseases,manifesting as the decline of... Sarcopenia is a progressive systemic skeletal muscle disease induced by various physiological and pathological factors,including aging,malnutrition,denervation,and cardiovascular diseases,manifesting as the decline of skeletal muscle mass and function.Both exercise and nutrition produce beneficial effects on skeletal muscle growth and are viewed as feasible strategies to prevent sarcopenia.Mechanisms involve regulating blood flow,oxidative stress,inflammation,apoptosis,protein synthesis and degradation,and satellite cell activation through exerkines and gut microbiomes.In this review,we summarized and discussed the latest progress and future development of the above mechanisms for providing a theoretical basis and ideas for the prevention and treatment of sarcopenia. 展开更多
关键词 Skeletal muscle SARCOPENIA EXERCISE Diet Exerkines Signaling pathway Satellite cells
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