In our previous studies, agmatine was found to prevent substance dependence of morphine in mice, rats and monkeys,but the exact mechanism was not clear yet. In this study, for the first time rat μ opioid receptor (rM...In our previous studies, agmatine was found to prevent substance dependence of morphine in mice, rats and monkeys,but the exact mechanism was not clear yet. In this study, for the first time rat μ opioid receptor (rMOR) and human I1-imidazoline receptor (hI1 R) were co-expressed stably in CHO cells (CHO-μ/I1) by means of lipofectamine展开更多
文摘In our previous studies, agmatine was found to prevent substance dependence of morphine in mice, rats and monkeys,but the exact mechanism was not clear yet. In this study, for the first time rat μ opioid receptor (rMOR) and human I1-imidazoline receptor (hI1 R) were co-expressed stably in CHO cells (CHO-μ/I1) by means of lipofectamine
