Measurement the viscoelastic properties is important for studying the developmental and pathological behavior of soft biological tissues.Magnetic resonance elastography(MRE)is a non-invasive method for in vivo measure...Measurement the viscoelastic properties is important for studying the developmental and pathological behavior of soft biological tissues.Magnetic resonance elastography(MRE)is a non-invasive method for in vivo measurement of tissue viscoelasticity.As a flexible method capable of testing small samples,indentation has been widely used for characterizing soft tissues.Using 2nd-order Prony series and dimensional analysis,we analyzed and compared the model parameters estimated from both indentation and MRE.Conversions of the model parameters estimated from the two methods were established.We found that the indention test is better at capturing the dynamic response of tissues at a frequency less than 10 Hz,while MRE is better for describing the frequency responses at a relatively higher range.The results provided helpful information for testing soft tissues using indentation and MRE.The models analyzed are also helpful for quantifying the frequency response of viscoelastic tissues.展开更多
基金This work was supported by the National Natural Science Foundation of China(Grant 31870941)Shanghai Science and Technology Committee(Grant 1944190700).
文摘Measurement the viscoelastic properties is important for studying the developmental and pathological behavior of soft biological tissues.Magnetic resonance elastography(MRE)is a non-invasive method for in vivo measurement of tissue viscoelasticity.As a flexible method capable of testing small samples,indentation has been widely used for characterizing soft tissues.Using 2nd-order Prony series and dimensional analysis,we analyzed and compared the model parameters estimated from both indentation and MRE.Conversions of the model parameters estimated from the two methods were established.We found that the indention test is better at capturing the dynamic response of tissues at a frequency less than 10 Hz,while MRE is better for describing the frequency responses at a relatively higher range.The results provided helpful information for testing soft tissues using indentation and MRE.The models analyzed are also helpful for quantifying the frequency response of viscoelastic tissues.
