负压封闭引流术联合高压氧治疗四肢大面积软组织创伤患者的疗效及对IFN-γ、TNF-α水平的影响

【目的】探讨负压封闭引流术联合高压氧治疗四肢大面积软组织创伤患者的疗效及对肿瘤坏死因子-α(TNF-α)和干扰素-γ(IFN-γ)水平的影响。【方法】选取2019年4月至2022年4月山东大学附属山东省立第三医院收治的100例四肢大面积软组织创伤患者,按照随机数字表法分为对照组和观察组,每组50例,对照组采用负压封闭引流术治疗,观察组在对照组基础上辅以高压氧治疗。治疗2周后,比较两组临床疗效、换药频率、住院时间、视觉模拟评分法(VAS)评分、炎症指标(TNF-α和IFN-γ)和不良反应发生率。【结果】观察组临床疗效优于对照组(P<0.05),住院时间短于对照组(P<0.05);两组治疗48 h后、治疗2周后VAS评分均低于本组治疗前(P<0.05),且观察组治疗2周后VAS评分低于对照组(P<0.05);治疗后,两组血清TNF-α和IFN-γ水平均低于治疗前(P<0.05),且观察组低于对照组(P<0.05);两组总不良反应发生率比较,差异无统计学意义(P>0.05)。【结论】负压封闭引流术联合高压氧应用于四肢大面积软组织创伤治疗中,有助于促进患者创面修复,抑制炎症因子表达,减轻患者术后疼痛,提高治疗效果且安全性良好,值得临床推广应用。

破片撞击损伤装药点火数值模拟

为了研究冲击波和破片撞击复合作用下装药点火机理,采用先冲击波损伤装药、后破片撞击已损伤装药的实验方法,获得受冲击装药点火对应的破片临界撞击速度为446.9～449.4 m·s^(-1)。采用LS?DYNA程序,基于节点约束?分离法对装药冲击波损伤进行数值模拟,而后用完全重启动方法对冲击损伤装药在破片撞击下的点火反应过程进行二次模拟,通过"升?降"法得到受冲击损伤装药点火对应的破片临界撞击速度为452～453 m·s^(-1),实验和数值模拟结果吻合较好。结果表明,可采用节点约束?分离方法和完全重启动数值模拟技术进行冲击波和破片复合作用下装药点火数值模拟;受冲击波损伤装药的破片撞击点火临界速度明显要低于未损伤装药,装药受损伤状态对破片撞击感度起到了敏化作用,从而降低了破片撞击点火的临界速度。

隧道掘进爆破破岩数值模拟及应用研究

为研究隧道掘进多孔毫秒延期爆破条件下的岩体破碎和爆破振动规律,采用完全重启动数值模拟技术和拉格朗日数值算法计算隧道掘进爆破破岩过程,得到了岩体特征点的振动速度,并将数值模拟评估的爆破方案应用于工程实践,数值模拟与工程实践结果比较吻合.结果表明,联合完全重启动数值模拟技术和拉格朗日算法能够模拟隧道破岩的物理力学过程.

金背杜鹃叶化学成分研究

目的研究金背杜鹃叶乙酸乙酯部位的化学成分。方法葡聚糖凝胶柱层析、结晶、重结晶和硅胶柱层析等方法对乙酸乙酯部分进行系统的分离纯化,通过理化方法和波谱数据进行分析和结构鉴定。结果从金背杜鹃叶的乙酸乙酯部位中分离鉴定了10个化合物,分别为槲皮素(1)、金丝桃苷(2)、3,7-二甲氧基-5,3',4'-三羟基黄酮(3)、乌苏醇(4)、(R)-杜鹃醇-2-O-β-D-吡喃葡萄糖苷(5)、4'-甲氧基-5,7,3'-三羟基黄酮(6)、广寄生苷(7)、廖属苷(8)、(+)儿茶素(9)、β-谷甾醇(10)。结论化合物4~6为首次从该植物中分离得到。

咳露口服液(无糖型)的抑菌效力评价

目的 按中国药典2015年版通则1121抑菌效力检查法测定咳露口服液(无糖型)的抑菌效力。方法 以金黄色葡萄球菌、铜绿假单胞菌、大肠埃希菌、白色念珠菌和黑曲霉为试验菌株,进行菌落计数方法学验证,然后进行微生物的挑战试验,按验证方法测定各时间点的菌落数。结果 咳露口服液(无糖型)抑菌效力不符合中国药典2015年版通则1121抑菌效力检查法的规定。结论 现有的抑菌剂处方需要进一步优化。

Effects of biofertilizers and super absorbent polymers on plant growth and soil fertility in the arid mining area of Inner Mongolia,China

A pot experiment was conducted in the Institute of Tianlong Ecology of Baotou City in Inner Mongolia, China, to investigate the effects of the application of biofertilizers and super absorbent polymers(SAP) on plant growth and soil improvement in arid mining area soil. Two typical species, namely, Syringa oblata Lindl.(SO) and Medicago sativa L.(MS), were present in the Bayan Obo mining area and used as representatives of shrubs and herbaceous plants in the pot experiment.(1) Biofertilizers and SAP significantly increased the tree height, the ground diameter of SO, and the total biomass of MS and improved the soil fertility of the mining area, especially its biological fertility, compared with those of the control group(CK). The application of biofertilizers and SAP decreased the mining soil p H and significantly increased available nitrogen, available phosphorus, available potassium, and soil organic matter.(2) After 180 days of growth, the microbial population(bacteria, fungi, and actinomycetes) and soil microbial biomass carbon and nitrogen significantly increased. Microbial ratios C: N significantly decreased compared with those of CK.(3) T5 and T6 treatments with the following dosages might be the optimum selection for the improvement of the studied mining area soil: 20 g SAP + 15 g biofertilizers(SO), 100 g/m2 SAP + 150 g biofertilizers(MS); 20 g SAP + 30 g biofertilizers(SO), and 100 g/m2 SAP + 200 g biofertilizers(MS). This study provided a promising reference for conducting future field studies and the local vegetation restoration.

智能化膝关节康复仪结合持续被动活动对胫骨平台骨折术后康复效果的影响

【目的】分析智能化CPM康复仪结合持续被动活动对胫骨平台骨折术后康复效果的影响。【方法】选取2019年5月至2021年5月于本院收治的胫骨平台骨折患者84例作为研究对象,随机将其分为观察组和对照组,每组42例。对照组给予持续被动活动康复训练,而观察组在对照组基础上联合智能化CPM康复仪器治疗。比较两组通过不同康复训练方案进行干预后,患者疼痛程度、膝关节肿胀度以及膝关节功能好转情况。【结果】治疗2周、4周、6周及8周后,两组膝关节肿胀度均小于术前(P<0.05);且观察组患者膝关节肿胀度小于对照组患者,组间差异具有统计学意义(P<0.05)。观察组患者术后视觉模拟疼痛评分(VAS)较对照组明显偏低,而HSS膝关节量表评分明显高于对照组,差异均有统计学意义(P<0.05)。【结论】智能化CPM康复仪结合持续被动活动训练对胫骨平台骨折术后康复有促进作用,可有效祛除膝关节水肿和减轻疼痛程度,改善膝关节功能。

Causes and typical control model of wind-drift sandy lands in abandoned channel of the Yellow River

The historical formation and development of the abandoned channel of the Yellow River is reviewed and its causes of formation and present condition of prevention and control are analyzed in this paper. Based on this analysis, some ideas about control, critical problems and countermeasures in the next period are proposed with two typical control models as examples. We suggest that in preventing and controlling the wind-drift sandy lands in the region, the emphasis should be to develop, with a greatly expanded effort, a recycling economy. This should realize a combination of two ideas, i.e. integrate combating desertification with a structural adjustment of agricultural and an increase in the income of farmers.

Evaluation of Potential Land Productivity in Wulushan, West China

The general situation of the total land resources in Wulushan, West China was studied by field investigations with the aid of a GIS software, called Region Manager. The current status of land use in Wulushan is described. The potential land productivity was evaluated by a fuzzy comprehensive method, We take each plot as a basic unit of evaluation on the basis of an index system of land resources in Wulushan which was developed from the investigation data. Evaluation of potential land productivity is the key part of land management. A guideline is presented in this paper for a proper utilization of the land resources and to develop the productive capacity of the land.

一种处理煤焦油加工企业硫酸钠废液的新方法及装置

以马钢奥瑟亚化工有限公司焦油酸洗涤分解单元为研究对象,探索一种新的硫酸钠废液的处理方法,通过在洗涤分解单元增加部分装置和对现有装置进行重新优化,改变以往硫酸钠废液的处理方式,实现在焦油加工生产过程中洗涤分解单元水的循环使用,生产单元无废液排出,降低了废液处理的风险和费用。

保水剂与微生物菌剂对土壤水分、养分的影响

保水剂与其他肥料混施,可以在不同程度上改善土壤的水分和养分条件,促进植物生长。通过将聚丙烯酸钾盐型保水剂与微生物菌剂混合对油松、紫花苜蓿进行盆栽试验,通过对低、中、高（油松：10、20、30 g·株^-1;紫花苜蓿：20、30、40 g·m^-2）保水剂和低、中、高（油松：5、10、20 g·株^-1;紫花苜蓿：15、30、45 g·m^-2）微生物菌剂混施,分析土壤水分和土壤中速效氮、磷、钾含量变化,及其对土壤水分、养分和植物生长的影响。结果表明：不同处理不同程度地提高了土壤速效氮、磷、钾含量以及土壤含水量。高浓度保水剂和高浓度微生物菌剂混施对一年生油松土壤速效氮促进最显著,低浓度保水剂和中浓度微生物菌剂混施对土壤速效磷、速效钾促进最显著,分别较对照组提高12%、35%和36%;紫花苜蓿高浓度保水剂和高浓度微生物菌剂混施对土壤速效氮、速效磷促进最显著,低浓度保水剂和中浓度微生物菌剂混施对土壤速效钾促进最显著,分别较对照组提高35%、27%和40%。中浓度保水剂和中浓度菌剂混施处理下土壤保水效果最优,而对油松和紫花苜蓿生长的影响达到最佳的分别为低浓度保水剂与低浓度菌剂混施和低浓度保水剂与中浓度菌剂混施。