Aim:The prevalence of epilepsy is higher in Nepal.This study was conducted to analyze the clinical manifestations of neurocysticercosis(NCC)among seizure patients admitted to our center.Methods:We retrospectively stud...Aim:The prevalence of epilepsy is higher in Nepal.This study was conducted to analyze the clinical manifestations of neurocysticercosis(NCC)among seizure patients admitted to our center.Methods:We retrospectively studied all the NCC patients admitted to Neurology Department,Bir Hospital,Kathmandu,Nepal from April 2012 to February 2014.Computer tomography/magnetic resonance imaging(CT/MRI)head,clinical profile,lab investigations and exclusion of other causes were the basis of the NCC diagnosis.Chi-square and Student’s t-test were used for comparison of variables.Results:Out of 131 seizure patients admitted,21 patients were diagnosed with NCC[mean age:33.95±16.41;male:15(71.4%),female:6(28.6%)].Generalized tonic clonic seizure was the most common seizure type in NCC patients(18 patients;85.7%),two of them had status epilepticus during presentation in Emergency Department.Three patients had focal seizure,one with epilepsia partialis continua.Neuroimaging showed multiple NCC lesions in 8(38.1%)and a single NCC lesion in 13(61.9%)patients.Seven of them(33.3%)sought traditional healers before being presented to our center.Eight patients(38.1%)were treated with antiepileptics in local health-post without neuroimaging studies done.Calcified stage of NCC was the most frequent CT/MRI findings(12 patients;57.1%).Phenytoin was preferred both by physicians and patients due to its low cost.Conclusion:NCC is a common finding among seizure patients in Nepal.Poor economic status,illiteracy and underdeveloped rural society are the major challenges in prevention and treatment of NCC.展开更多
文摘Aim:The prevalence of epilepsy is higher in Nepal.This study was conducted to analyze the clinical manifestations of neurocysticercosis(NCC)among seizure patients admitted to our center.Methods:We retrospectively studied all the NCC patients admitted to Neurology Department,Bir Hospital,Kathmandu,Nepal from April 2012 to February 2014.Computer tomography/magnetic resonance imaging(CT/MRI)head,clinical profile,lab investigations and exclusion of other causes were the basis of the NCC diagnosis.Chi-square and Student’s t-test were used for comparison of variables.Results:Out of 131 seizure patients admitted,21 patients were diagnosed with NCC[mean age:33.95±16.41;male:15(71.4%),female:6(28.6%)].Generalized tonic clonic seizure was the most common seizure type in NCC patients(18 patients;85.7%),two of them had status epilepticus during presentation in Emergency Department.Three patients had focal seizure,one with epilepsia partialis continua.Neuroimaging showed multiple NCC lesions in 8(38.1%)and a single NCC lesion in 13(61.9%)patients.Seven of them(33.3%)sought traditional healers before being presented to our center.Eight patients(38.1%)were treated with antiepileptics in local health-post without neuroimaging studies done.Calcified stage of NCC was the most frequent CT/MRI findings(12 patients;57.1%).Phenytoin was preferred both by physicians and patients due to its low cost.Conclusion:NCC is a common finding among seizure patients in Nepal.Poor economic status,illiteracy and underdeveloped rural society are the major challenges in prevention and treatment of NCC.
