Evaluation of antioxidant and anti-hypercholesterolemic potential of Vitis vinifera leaves

Background:Vitis vinifera is universally appreciated herb(especially fruit)for their delicacy,nutrition and conventional as functional food.In the present study,we evaluated anti-hypercholesterolemic potential of Vitis vinifera red leaves extract in experimental wistar male rats.Material and methods:Qualitative and quantitative phytochemical screening of vitis vinifera methanolic extract(VVME)and vitis vinifera aqueous extract aqueous(VVAE)extract was carried out to identify the phytoconstituents.The anti-hypercholesterolemic activity was evaluated by inducing hypercholesterolemia with high cholesterol diet for 21 days in experimental animals.During the experimental periods parameters like lipid profile,liver function test,atherogenic index and histopathological studies were analysed.Results:Total tannins,total flavonoids and total phenolic contents were found in major amount in VVME.The lipid levels were significantly attenuated by different doses of VVME and VVAE.Moreover,VVME was found more effective than VVAE and histopathological results confirmed the effectiveness of VVME.Conclusion:It can be concluded that anti-hypercholesterolemic efficacy of Vitis vinifera might be due to presence of active phytoconstituents and its antioxidant efficacy.

Synthesis and photoluminescent performance of novel europium(Ⅲ) carboxylates with heterocyclic ancillary ligands

Five novel europium(Ⅲ)complexes with 2-[4-(dibutylamino)-2-hydroxybenzoyl]benzoic acid(DAHB)as primary ligand and bathophenanthroline(batho),2,2’-bipyridyl(bipy),5,6-dimethyl-1,10-phenanthroline(dmph),1,10-phenanthroline(phen)as ancillary ligands were syn-thesized via solution precipitation method.The structural formulae of synthesized complexes were speculated to be Eu(DABH)_(3)·2H_(2)O(C1),Eu(DABH)_(3)·batho(C2),Eu(DABH)_(3)·bipy(C3),Eu(DABH)_(3)·dmph(C4)and Eu(DABH)_(3)·phen(C5)by elemental analysis,infrared spectroscopy and proton nuclear magnetic resonance spec-troscopy(^(1)H-NMR).The photoluminescent properties and thermal stability of the complexes were investigated by photoluminescent spectroscopy and thermogravimetric analysis(TG-DTG),respectively.The Commission Inter-nationale de I’Eclairage(CIE)color coordinates,Judd–Ofelt intensity parameter(Ω_(2)),total quantum yield,intrinsic quantum efficiency and energy transfer dynamics of com-plexes were also explored.The excitation spectra of com-plexes are extended up to visible region.These complexes exhibit characteristic photoemission of Eu^(3+)metal ion with high color purity in red region attributed to efficient energy transfer from ligand to metal ion.The replacement of water molecules from coordination sphere of europium ion by ancillary ligands results in enhancement of luminescent properties of the C2–C5 complexes,indicating that ancillary ligands act as additional light harvesting centers in sensiti-zation phenomenon.The thermal studies show that these complexes are suitable for meeting the requirement of temperature for fabrication of OLEDs devices.