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IPNA临床实践建议:儿童激素敏感型肾病综合征的诊断和治疗 被引量:1
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作者 Agnes Trautmann Olivia Boyer +22 位作者 Elisabeth Hodson Arvind Bagga Debbie S.Gipson Susan Samuel Jack Wetzels Khalid Alhas an sushmita banerjee Rajendra Bhimma Melvin Bonilla-Felix Francisco Cano Martin Christian Deirdre Hahn Hee Gyung Kang Koichi Nakanishi Hesham Safouh Howard Trachtman Hong Xu Wendy Cook Marina Vivarelli Dieter Hafner on behalf of the International Pediatric Nephrology Association 韩思雨(翻译) 季丽娜(翻译) 《中国合理用药探索》 2023年第2期1-35,共35页
特发性肾病综合征是最常见的儿童肾小球疾病,其特征是大量蛋白尿、低蛋白血症和(或)伴有水肿,全球每年儿童患病率为(1.15~16.90)每10万例。约有85%~90%的患者在接受糖皮质激素治疗的4~6周内可达到蛋白尿完全缓解,表现为激素敏感型肾病... 特发性肾病综合征是最常见的儿童肾小球疾病,其特征是大量蛋白尿、低蛋白血症和(或)伴有水肿,全球每年儿童患病率为(1.15~16.90)每10万例。约有85%~90%的患者在接受糖皮质激素治疗的4~6周内可达到蛋白尿完全缓解,表现为激素敏感型肾病综合征(SSNS)。约70%~80%的SSNS患者在随访期间至少复发1次,其中多达50%的患者出现频繁复发或依赖糖皮质激素以维持蛋白尿缓解。为延长复发间隔时间,激素治疗的用药剂量和用药时长始终是热点问题之一,且患者出现激素相关并发症的概率较高。临床已应用多种激素助减药物(免疫抑制药物),但在疾病治疗过程中这些药物的选择和用药时机存在明显差异。因此,需要国际循证临床实践建议(CPRs)来指导临床实践、减少实践差异。国际儿科肾脏病学会(IPNA)召集专家小组通过对12个临床相关PICO(研究对象、干预措施、对照、结果/结局)问题进行系统的文献回顾,制定了关于儿童SSNS诊断和治疗的建议和分级。对治疗转归提出了新的定义,有助于指导治疗改变,并为重要的研究问题提供了参考。 展开更多
关键词 激素敏感型肾病综合征 儿童 频复发型肾病综合征 激素依赖型肾病综合征 激素毒性 儿科 免疫抑制治疗
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Ionization of Hydrogenic 3d State by Electron Impact
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作者 sushmita banerjee Sunil Dhar 《Open Journal of Microphysics》 2019年第4期29-39,共11页
The triple differential cross sections estimation have been ascertained theoretically for the ionization of metastable 3d-state hydrogen atoms by electron at 150 eV, 200 eV and 250 eV for assorted kinematic conditions... The triple differential cross sections estimation have been ascertained theoretically for the ionization of metastable 3d-state hydrogen atoms by electron at 150 eV, 200 eV and 250 eV for assorted kinematic conditions exerting a multiplex scattering principle. The existent new-findings are assimilated with the theoretic data of hydrogenic metastable 2S, 3S and 3P states as well as the hydrogenic ground state experiment. An analysis of the attained observations reveals qualitative fitness with those of compared results specially with hydrogenic ground state BBK model, ground state experimental data and metastable state 2S state results. This is a new theoretical work on hydrogenic metastable 3d state ionization by electron. The substantial progress of the current study offers a wide scope for empirical study in ionization process. 展开更多
关键词 ELECTRON IONIZATION CROSS-SECTION SCATTERING
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Triple Differential Cross-Sections for Ionization of H(3d) by Incident Electron
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作者 sushmita banerjee Sunil Dhar Amanul Hoque 《Open Journal of Microphysics》 2018年第4期30-41,共12页
Triple differential cross sections (TDCS) are estimated for the ionization of metastable 3d-state hydrogen atoms by electron at 250 eV for various kinematic conditions pursuing a multiple scattering theory. The presen... Triple differential cross sections (TDCS) are estimated for the ionization of metastable 3d-state hydrogen atoms by electron at 250 eV for various kinematic conditions pursuing a multiple scattering theory. The present new results are compared with the theoretical results of hydrogenic different metastable states as well as the hydrogenic ground state experimental data. Obtained new finding results are in good qualitative agreement with those of compared theories. The present results give an immense opportunity for experimental trial in the field of ionization problems. 展开更多
关键词 ELECTRON IONIZATION CROSS-SECTIONS SCATTERING
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First Born Double Differential Cross-Section for Ionization of H (3d) by Incident Electron Impact
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作者 sushmita banerjee Sunil Dhar 《Open Journal of Microphysics》 2024年第2期67-77,共11页
Double differential cross section (DDCS) of First-Born approximation is calcu-lated for the ionization of metastable 3d-state hydrogen atoms by electron impact energy at 150 eV and 250 eV. A multiple scattering theory... Double differential cross section (DDCS) of First-Born approximation is calcu-lated for the ionization of metastable 3d-state hydrogen atoms by electron impact energy at 150 eV and 250 eV. A multiple scattering theory is applied in the present study. The present results are compared with the other related the-oretical results for the ionization of hydrogen atoms from different metastable states and ground-state experimental results. The findings demonstrate a strong qualitative agreement with the existing results. The obtained results have an extensive scope for further study of such an ionization process. 展开更多
关键词 Electron Ionization Cross-Section Scattering
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