Background: Childhood Tuberculosis (TB) is an important cause of mortality and morbidity, which causes a significant TB burden in developing countries. Objectives: The aim of this study was to describe clinical profil...Background: Childhood Tuberculosis (TB) is an important cause of mortality and morbidity, which causes a significant TB burden in developing countries. Objectives: The aim of this study was to describe clinical profile and diagnostic procedures used in Outpatient Department (OPD) of a tertiary care hospital. Methods: It was a retrospective study conducted in OPD of Paediatrics Department, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh. Age range of studied populations, 3 months to 18 years who presented with clinical features of TB and were later diagnosed with tuberculosis according to national guidelines for the management of tuberculosis in children, 2021 were enrolled in this study. A total of 108 diagnosed cases of Tuberculosis between August 2021 and July 2022 were enrolled in this study. Data were collected from OPD records and transferred into MS excel sheet for data processing & analysis. Results: Among 834 suspected patients, 108 patients aged 3 months to 18 years were diagnosed with tuberculosis. The highest number of cases 47 (43.51%) were found in 11 - 18 years age group. Gender distribution of the patient showed 58 (53.70%) were male and 50 (46.29%) were female. Among 108 TB cases, 44 (40.74%) were pulmonary TB and 64 (59.25%) were extrapulmonary TB. Among 64 extrapulmonary TB cases 38 (59.37%) cases were diagnosed as TB lymphadenitis. Fever 83 (76.85%), weight loss 62 (57.4%), cough 50 (46.29%), lump in neck and axilla 38 (35.18%) were found in most of the cases. A positive Mantoux test was found in 68 (62.96%) patients. Chest X-ray findings showed patchy opacity and consolidation in 46 (42.59%) cases. Suggestive FNAC from lymph node was observed among 35 (32.4%) cases. For bacteriological confirmation sputum gene Xpert and stool Xpert ultra were positive among 10 (9.25%) and 23 (21.29%) cases. Conclusion: In this study, Extrapulmonary TB (EPTB) cases were more than Pulmonary TB (PTB) in children. Diagnosis of tuberculosis was based on<span sty.展开更多
Background: Children are generally at low risk of infection and data on COVID-19 in children are scarce. This study was undertaken to document data from a tertiary care hospital in Bangladesh on the incidence, present...Background: Children are generally at low risk of infection and data on COVID-19 in children are scarce. This study was undertaken to document data from a tertiary care hospital in Bangladesh on the incidence, presentation and immediate outcome of COVID-19 in children. Methodology: It was a cross-sectional study conducted in the fever clinic and the department of Pediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU) over a period of one year from July 2020 to June 2021. All the RT–PCR positive pediatric cases (1 month to 18 years) were enrolled. Data were collected by a structured, predesigned and pre-tested questionnaire. Data were analyzed using Microsoft Excel spreadsheet software 2010. Frequency, percentage and chi-square tests were done for statistical analysis. Result: Among 8203 suspected pediatric COVID-19 cases, 850 (10.36%) was RT PCR positive. The highest number of RT-PCR positive COVID-19 cases was found in April 2021. More than 63% of cases were in the age group of 10 to 18 years. Male: female ratio was 0.97:1. Fever was the most common (75.9%) presenting feature followed by breathing difficulty and chest pain in 9.6% and 7% of <span style="font-family: ">patients respectively. Mild infection group was predominant (56.7%). Among the symptomatic cases, 16.7% were hospitalized. Oxygen inhalation and bronchodilators were needed in 75% of hospitalized patients. All the severe and critical cases were managed in the inpatient department and in pediatric PICU when indicated. Most of the patients (99.4%) improved with or without any complication. Four critically ill patients (0.75%) developed multi-organ dysfunction and expired in PICU. Conclusion: <span style="font-family: ">The majority of COVID-19 cases belonged to the older age group. More than 75% cases were symptomatic. History of contact was present in 78% cases. More than 99% children recovered with or without sequelae and 0.8% children with pre-existing co-morbidities expired.展开更多
文摘Background: Childhood Tuberculosis (TB) is an important cause of mortality and morbidity, which causes a significant TB burden in developing countries. Objectives: The aim of this study was to describe clinical profile and diagnostic procedures used in Outpatient Department (OPD) of a tertiary care hospital. Methods: It was a retrospective study conducted in OPD of Paediatrics Department, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh. Age range of studied populations, 3 months to 18 years who presented with clinical features of TB and were later diagnosed with tuberculosis according to national guidelines for the management of tuberculosis in children, 2021 were enrolled in this study. A total of 108 diagnosed cases of Tuberculosis between August 2021 and July 2022 were enrolled in this study. Data were collected from OPD records and transferred into MS excel sheet for data processing & analysis. Results: Among 834 suspected patients, 108 patients aged 3 months to 18 years were diagnosed with tuberculosis. The highest number of cases 47 (43.51%) were found in 11 - 18 years age group. Gender distribution of the patient showed 58 (53.70%) were male and 50 (46.29%) were female. Among 108 TB cases, 44 (40.74%) were pulmonary TB and 64 (59.25%) were extrapulmonary TB. Among 64 extrapulmonary TB cases 38 (59.37%) cases were diagnosed as TB lymphadenitis. Fever 83 (76.85%), weight loss 62 (57.4%), cough 50 (46.29%), lump in neck and axilla 38 (35.18%) were found in most of the cases. A positive Mantoux test was found in 68 (62.96%) patients. Chest X-ray findings showed patchy opacity and consolidation in 46 (42.59%) cases. Suggestive FNAC from lymph node was observed among 35 (32.4%) cases. For bacteriological confirmation sputum gene Xpert and stool Xpert ultra were positive among 10 (9.25%) and 23 (21.29%) cases. Conclusion: In this study, Extrapulmonary TB (EPTB) cases were more than Pulmonary TB (PTB) in children. Diagnosis of tuberculosis was based on<span sty.
文摘Background: Children are generally at low risk of infection and data on COVID-19 in children are scarce. This study was undertaken to document data from a tertiary care hospital in Bangladesh on the incidence, presentation and immediate outcome of COVID-19 in children. Methodology: It was a cross-sectional study conducted in the fever clinic and the department of Pediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU) over a period of one year from July 2020 to June 2021. All the RT–PCR positive pediatric cases (1 month to 18 years) were enrolled. Data were collected by a structured, predesigned and pre-tested questionnaire. Data were analyzed using Microsoft Excel spreadsheet software 2010. Frequency, percentage and chi-square tests were done for statistical analysis. Result: Among 8203 suspected pediatric COVID-19 cases, 850 (10.36%) was RT PCR positive. The highest number of RT-PCR positive COVID-19 cases was found in April 2021. More than 63% of cases were in the age group of 10 to 18 years. Male: female ratio was 0.97:1. Fever was the most common (75.9%) presenting feature followed by breathing difficulty and chest pain in 9.6% and 7% of <span style="font-family: ">patients respectively. Mild infection group was predominant (56.7%). Among the symptomatic cases, 16.7% were hospitalized. Oxygen inhalation and bronchodilators were needed in 75% of hospitalized patients. All the severe and critical cases were managed in the inpatient department and in pediatric PICU when indicated. Most of the patients (99.4%) improved with or without any complication. Four critically ill patients (0.75%) developed multi-organ dysfunction and expired in PICU. Conclusion: <span style="font-family: ">The majority of COVID-19 cases belonged to the older age group. More than 75% cases were symptomatic. History of contact was present in 78% cases. More than 99% children recovered with or without sequelae and 0.8% children with pre-existing co-morbidities expired.
