AIM: To evaluate the image quality of hepatic multidetector computed tomography(MDCT) with dynamic contrast enhancement. METHODS: It uses iodixanol 270 mg/m L(Visipaque 270) and 80 kVp acquisitions reconstructed with ...AIM: To evaluate the image quality of hepatic multidetector computed tomography(MDCT) with dynamic contrast enhancement. METHODS: It uses iodixanol 270 mg/m L(Visipaque 270) and 80 kVp acquisitions reconstructed with sinogram affirmed iterative reconstruction(SAFIRE?) in comparison with a standard MDCT protocol. Fiftythree consecutive patients with known or suspected hepatocellular carcinoma underwent 55 CT examinations, with two different four-phase CT protocols. The first group of 30 patients underwent a standard 120 kVp acquisition after injection of Iohexol 350 mg/m L(Accupaque 350~?) and reconstructed with filtered back projection. The second group of 25 patients underwent a dual-energy CT at 80-140 kVp with iodixanol 270. The 80 kVp component of the second group was reconstructed iteratively(SAFIRE?-Siemens). All hyperdense and hypodense hepatic lesions ≥ 5 mm were identified with both protocols. Aorta and portal vessels/liver parenchyma contrast to noise ratio(CNR) in arterial phase, hypervascular lesion/liver parenchyma CNR in arterial phase, hypodense lesion/liver parenchyma CNR in portal and late phase were calculated in both groups.RESULTS: Aorta/liver and focal lesions altogether/liver CNR were higher for the second protocol(P = 0.0078 and 0.0346). Hypervascular lesions/liver CNR was not statistically different(P = 0.86). Hypodense lesion/liver CNR in the portal phase was significantly higher for the second group(P = 0.0107). Hypodense lesion/liver CNR in the late phase was the same for both groups(P = 0.9926).CONCLUSION: MDCT imaging with 80 kVp with iterative reconstruction and iodixanol 270 yields equal or even better image quality.展开更多
文摘AIM: To evaluate the image quality of hepatic multidetector computed tomography(MDCT) with dynamic contrast enhancement. METHODS: It uses iodixanol 270 mg/m L(Visipaque 270) and 80 kVp acquisitions reconstructed with sinogram affirmed iterative reconstruction(SAFIRE?) in comparison with a standard MDCT protocol. Fiftythree consecutive patients with known or suspected hepatocellular carcinoma underwent 55 CT examinations, with two different four-phase CT protocols. The first group of 30 patients underwent a standard 120 kVp acquisition after injection of Iohexol 350 mg/m L(Accupaque 350~?) and reconstructed with filtered back projection. The second group of 25 patients underwent a dual-energy CT at 80-140 kVp with iodixanol 270. The 80 kVp component of the second group was reconstructed iteratively(SAFIRE?-Siemens). All hyperdense and hypodense hepatic lesions ≥ 5 mm were identified with both protocols. Aorta and portal vessels/liver parenchyma contrast to noise ratio(CNR) in arterial phase, hypervascular lesion/liver parenchyma CNR in arterial phase, hypodense lesion/liver parenchyma CNR in portal and late phase were calculated in both groups.RESULTS: Aorta/liver and focal lesions altogether/liver CNR were higher for the second protocol(P = 0.0078 and 0.0346). Hypervascular lesions/liver CNR was not statistically different(P = 0.86). Hypodense lesion/liver CNR in the portal phase was significantly higher for the second group(P = 0.0107). Hypodense lesion/liver CNR in the late phase was the same for both groups(P = 0.9926).CONCLUSION: MDCT imaging with 80 kVp with iterative reconstruction and iodixanol 270 yields equal or even better image quality.
