An efficient Pd-catalyzed method for C—O cross-coupling of ketoximes and chalcone oximes with activated aryl bromides and bromo-chalcones has been developed.All oxime ethers were obtained in good to excellent yields ...An efficient Pd-catalyzed method for C—O cross-coupling of ketoximes and chalcone oximes with activated aryl bromides and bromo-chalcones has been developed.All oxime ethers were obtained in good to excellent yields by[(π-allyl)PdCl]2/tBuXPhos(L7)catalyst system.TrixiePhos(L11)was also found to be effective for the oxime coupling.This method offers an easy and smooth coupling of chalcone oximes with activated aryl bromides and bromo-chalcones,which has not been previously explored.展开更多
文摘An efficient Pd-catalyzed method for C—O cross-coupling of ketoximes and chalcone oximes with activated aryl bromides and bromo-chalcones has been developed.All oxime ethers were obtained in good to excellent yields by[(π-allyl)PdCl]2/tBuXPhos(L7)catalyst system.TrixiePhos(L11)was also found to be effective for the oxime coupling.This method offers an easy and smooth coupling of chalcone oximes with activated aryl bromides and bromo-chalcones,which has not been previously explored.
