A case of secretory breast carcinoma with ETV6-NTRK3 fusion gene during childhood

Secretory carcinoma is a rare breast cancer.We report a case of secretory carcinoma occurred in childhood.A 7-year-old girl had a history of a mass in the breast for 4 years.The tumor grew slowly and well circumscribed,mimicking benign lesions on imaging.After breast lumpectomy,a diagnosis of secretory carcinoma was made based on its histological morphology,immunohistochemical reaction,and molecular profile.Herein,we report the process of diagnosis,and treatment of this rare case.

兒童面部盤狀紅斑狼瘡1例報告

患兒男,11歲,右頰面部紅斑、雙耳部皮疹1月餘。1月餘前無明顯誘因下出現右頰面部紅斑、隨後雙耳及左頰面部出現類似情況。曾按過敏性皮炎抗過敏對症治療,無效。隨後,皮損緩慢增大、增厚,表面出現少量黏著性鱗屑,偶有輕度瘙癢。發病以來,一般情況良好,無發熱、關節痛、口腔潰瘍及光過敏現象。既往健康,家族中無結締組織病史。系統檢查未見異常,頸部淋巴結未觸及。