当前个人健康记录(PHR:Personal Health Records)存在着存储不安全和难以共享的问题。为提高PHR的安全性和共享性,提出一种基于超级帐本(Hyperledger)和手指静脉(FV:Finger Vein)特征身份验证的安全共享模型。PHR提供方在录入医疗记录时...当前个人健康记录(PHR:Personal Health Records)存在着存储不安全和难以共享的问题。为提高PHR的安全性和共享性,提出一种基于超级帐本(Hyperledger)和手指静脉(FV:Finger Vein)特征身份验证的安全共享模型。PHR提供方在录入医疗记录时将FV特征与临床医生的私钥签名结合,生成PHR索引。然后将PHR的索引存储在Hyperledger Fabric中,将真正的隐私数据存储在Filecoin中,减少了存储成本和链上存储压力。同时,设计了PHR访问控制合约防止恶意节点攻击。实验结果表明,该模型在性能和存储上有显著的优势。展开更多
Effective molecularly imprinted membranes（MIMs） were developed as an efficient adsorbent for the selective removal ofp-hydroxybenzoic acid（p-HB） from acetylsalicylic acid（ASA, aspirin）. The MIMs were grafted suc...Effective molecularly imprinted membranes（MIMs） were developed as an efficient adsorbent for the selective removal ofp-hydroxybenzoic acid（p-HB） from acetylsalicylic acid（ASA, aspirin）. The MIMs were grafted successfully from poly（vinylidene fluoride） microfiltration membranes via reversible addition-fragmentation chain transfer（RAFT） polymerization. The graft copolymerization of acrylic acid（AA） in the presence of template p-hydroxybenzoic acid led to molecularly imprinted polymer（MIP） film coated membranes. The obtained MIMs were characterized by scanning electron microscopy（SEM）, Fourier transform infrared spectrophotometer（FTIR） and Raman spectra, and batch mode adsorption studies were carried ont to investigate the specific adsorption equilibrium, kinetics and selective recognition properties of different MIMs. The kinetic properties of the MIMs could be well described by the pseudo-second-order rate equation. Selective permeation experiments were performed to evaluate the permeation selectivity of the p-HB imprinted membranes. The observed performances of the MIMs are applicable to the further purification of aspirin. Keywords Acetylsalicylic acid; Reversible addition-fragmentation chain transfer; Molecularly imprinted membrane; p-Hydroxybenzoic acid; Selective adsorption展开更多
文摘当前个人健康记录(PHR:Personal Health Records)存在着存储不安全和难以共享的问题。为提高PHR的安全性和共享性,提出一种基于超级帐本(Hyperledger)和手指静脉(FV:Finger Vein)特征身份验证的安全共享模型。PHR提供方在录入医疗记录时将FV特征与临床医生的私钥签名结合,生成PHR索引。然后将PHR的索引存储在Hyperledger Fabric中,将真正的隐私数据存储在Filecoin中,减少了存储成本和链上存储压力。同时,设计了PHR访问控制合约防止恶意节点攻击。实验结果表明,该模型在性能和存储上有显著的优势。
基金Supported by the National Natural Science Foundation of China（No.21606099）, the Natural Science Foundation of Jilin Province, China（No.20180623042TC） and the Science and Technology Research Foundation of the Department of Education of Jilin Province, China（Nos. JJKH20180 782KJ, JJKH20180761K J, JJKH20170376K J）.
文摘Effective molecularly imprinted membranes（MIMs） were developed as an efficient adsorbent for the selective removal ofp-hydroxybenzoic acid（p-HB） from acetylsalicylic acid（ASA, aspirin）. The MIMs were grafted successfully from poly（vinylidene fluoride） microfiltration membranes via reversible addition-fragmentation chain transfer（RAFT） polymerization. The graft copolymerization of acrylic acid（AA） in the presence of template p-hydroxybenzoic acid led to molecularly imprinted polymer（MIP） film coated membranes. The obtained MIMs were characterized by scanning electron microscopy（SEM）, Fourier transform infrared spectrophotometer（FTIR） and Raman spectra, and batch mode adsorption studies were carried ont to investigate the specific adsorption equilibrium, kinetics and selective recognition properties of different MIMs. The kinetic properties of the MIMs could be well described by the pseudo-second-order rate equation. Selective permeation experiments were performed to evaluate the permeation selectivity of the p-HB imprinted membranes. The observed performances of the MIMs are applicable to the further purification of aspirin. Keywords Acetylsalicylic acid; Reversible addition-fragmentation chain transfer; Molecularly imprinted membrane; p-Hydroxybenzoic acid; Selective adsorption
