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Second-trimester maternal β-human chorionic gonadotropin level associated with subsequent development of pregnancy-induced hypertension 被引量:2
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作者 tang longying Chen Qizhen +3 位作者 Zuo Wanxin Sun Tingwei Wang Yianshu Jin Hua 《Journal of Medical Colleges of PLA(China)》 CAS 2010年第5期293-297,共5页
Objective:To determine whether maternal β-human chorionic gonadotropin(β-hCG) level in second-trimester may be associated with subsequent development of pregnancy-induced hypertension(PIH).Methods:Seven hundred and ... Objective:To determine whether maternal β-human chorionic gonadotropin(β-hCG) level in second-trimester may be associated with subsequent development of pregnancy-induced hypertension(PIH).Methods:Seven hundred and sixty-two women in mid-trimester were to have maternal urine β-hCG standardized concentrations and maternal serum β-hCG measurements.Their case histories were recorded and reviewed from mid-trimester to delivery.The relation was observed between maternal urine,serum markers and subsequent development of PIH.Results:Among 762 women,504 cases were normal pregnancies,42 cases had PIH,94 cases had premature rupture of membrane (PROM),69 cases had preterm delivery (PD),53 other cases were excluded by various reasons.The levels of maternal urine,serum β-hCG in PIH were (61.75±9.78) IU/L and (304.56±54.17) ng/mg respectively,which were higher significantly than normal pregnancy group ([20.65±7.61] IU/L and [146.34±47.81] ng/mg,P<0.05).When maternal serum,urine β-hCG levels ≥2 MOM(multiple of mean),the incidences of developing PIH were increased significantly as compared with those of β-hCG <2 MOM women.The incidence of PIH increased from 5.1% in pregnancies with urine β-hCG ≥2 MOM to 11.7% in cases with urine β-hCG ≥4 MOM.Conclusion:The elevation of maternal mid-trimester urine,serum β-hCG levels is not only an early signal for dysfunction of placenta but also a dangerous signal for development of PIH.Second-trimester maternal urine β-hCG measurement proves to be superior to serum marker in clinical prediction. 展开更多
关键词 人绒毛膜促性腺激素 妊娠高血压综合征 激素水平 孕产妇 妊高征 HCG 发展中国家 PROM
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产前超声诊断胎儿成骨不全1例 被引量:1
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作者 张会萍 唐龙英 周毓青 《中国医学影像技术》 CSCD 北大核心 2022年第1期158-158,共1页
孕妇34岁,孕29^(+5)周,产检提示胎儿异常;孕1产0,孕23周前按期产检,胎儿均未见明显异常;其夫巩膜呈湖蓝色,幼年曾骨折数次。孕29^(+5)周超声:胎儿双顶径(biparietal diameter,BPD)75.6 mm,腹围(abdominal circumference,AC)242.2 mm,股... 孕妇34岁,孕29^(+5)周,产检提示胎儿异常;孕1产0,孕23周前按期产检,胎儿均未见明显异常;其夫巩膜呈湖蓝色,幼年曾骨折数次。孕29^(+5)周超声:胎儿双顶径(biparietal diameter,BPD)75.6 mm,腹围(abdominal circumference,AC)242.2 mm,股骨长(femur length,FL)50.0 mm,FL/AC为0.21,胎儿偏小,股骨未见明显弯曲;FL小于同孕周正常值1.61个标准差(standard deviation,SD),约同于孕26^(+6)周胎儿(图1A);考虑成骨发育不全等骨骼系统单基因疾病可能性大。孕31^(+5)周、孕38+4周复查胎儿超声,FL分别为52.9 mm、61.9 mm,小于同孕周正常值2.47个、3.10个SD,FL/AC均为0.19,股骨从稍弯曲(图1B)进展为双侧股骨明显弯曲(图1C),双侧肱骨稍弯曲。随孕周增加,胎儿FL偏短进行性加重(图2);BPD则始终在正常范围。孕妇于孕39周顺产一女婴,新生儿体质量2940 g,Apgar评分9分,巩膜呈白色;新生儿全外显子组基因测序检测结果显示父系来源(杂合)COL1A2基因c.1009G>A(p.Gly337Ser)变异,诊断为成骨不全(osteogenesis imperfecta,OI)。 展开更多
关键词 胎儿 成骨不全 超声检查
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1→N quantum controlled phase gate realized in a circuit QED system 被引量:4
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作者 GAO GuiLong CAI GenChang +4 位作者 HUANG.ShouSheng tang longying GU WenJing WANG MingFeng JIANG-NianQuan 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2012年第8期1422-1426,共5页
We propose an effective method to realize the quantum phase gate of one qubit simultaneously controlling N qubits. We use the system in which the transmon qubits are capacitively coupled to a superconducting transmiss... We propose an effective method to realize the quantum phase gate of one qubit simultaneously controlling N qubits. We use the system in which the transmon qubits are capacitively coupled to a superconducting transmission line resonator driven by a strong microwave field. In our scheme, the phase gate can be realized in a time (nanosecond-scale) much shorter than decoherence time (microsecond-scale), and it is more immune to the 1/f charge noise and has longer dephasing time due to the favorable properties of the transmon qubits in the system. 展开更多
关键词 量子系统 量子相位 量子控制 QED 电路 量子比特 相干时间 微波场驱动
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