为解决低温余热资源过剩与高温用热需求紧缺之间的矛盾,设计了一套基于准二级压缩的高温热泵机组,理论分析循环流程并进行优化设计,采用闪蒸器与回热器组合提高机组性能,开展了机组的性能实验,以制热量、制热COP、[火用]效率、冷凝压力...为解决低温余热资源过剩与高温用热需求紧缺之间的矛盾,设计了一套基于准二级压缩的高温热泵机组,理论分析循环流程并进行优化设计,采用闪蒸器与回热器组合提高机组性能,开展了机组的性能实验,以制热量、制热COP、[火用]效率、冷凝压力、排气温度为性能指标,在冷凝器出水温度为85~120℃,蒸发器进水温度为50、60、70℃工况下,对机组性能进行分析。实测机组性能与理论计算结果吻合,蒸发器进水温度为49.8℃,冷凝器出水温度为118.1℃,机组制热量可达916.3 k W,制热COP为2.51,[火用]效率为46.3%,机组冷凝压力为1.8 MPa,排气温度为137℃,符合机组安全运行的要求。展开更多
目的探究细胞增殖分化的Notch信号通路在曲安奈德治疗裸鼠血管瘤模型过程中的表达情况及其作用机制。方法选取2022年12月—2023年6月深圳市龙岗中心医院18只小鼠。分为Control组、Control+TA for 7 days处理组、Control+TA for 14 days...目的探究细胞增殖分化的Notch信号通路在曲安奈德治疗裸鼠血管瘤模型过程中的表达情况及其作用机制。方法选取2022年12月—2023年6月深圳市龙岗中心医院18只小鼠。分为Control组、Control+TA for 7 days处理组、Control+TA for 14 days处理组,每组6只,并进行相应给药处理,每3 d记录肿瘤生长状况,利用蛋白质免疫印迹(western blot,WB)和实时荧光定量聚合酶链式反应(real-time quantitative polymerase chain reaction,qPCR)检测糖皮质激素受体α(glucocorticoid receptorα,GRα)、Notch1、表皮生长因子受体(epidermal growth factor receptor,EGRF)和Split多毛增强子(hairy and enhancer of split,HES1)蛋白表达情况,免疫组化观察阳性细胞。结果WB实验结果显示,与Control组相比,Control+TA for 7 days处理组和Control+TA for 14 days处理组中GRα、Notch1和EGFR蛋白表达显著下降,而HES1蛋白显著上升,差异有统计学意义(P<0.05);qPCR实验结果显示,与对照组相比,Control+TA for 7 days处理组和Control+TA for 14 days处理组中GRα、Notch1和HES1蛋白表达显著下降,而EGFR蛋白显著上升,差异有统计学意义(P<0.05);免疫组化结果显示,与Control组相比,Control+TA for 7 days处理组免疫组化和Control+TA for 14 days处理组中GRα、Notch1、HES1和EGFR阳性细胞减少,差异有统计学意义(P<0.05)。结论曲安奈德可使裸鼠模型血管瘤组织GRα、Notch1表达下降,Notch信号通路参与曲安奈德治疗血管瘤的作用过程。展开更多
Adsorption of Neutral Red (NR) onto peanut husk in aqueous solutions was investigated at 295 K. Experiments were carried out as function of pH, adsorbent dosage, contact time, and initial concentration. The equilibriu...Adsorption of Neutral Red (NR) onto peanut husk in aqueous solutions was investigated at 295 K. Experiments were carried out as function of pH, adsorbent dosage, contact time, and initial concentration. The equilibrium adsorption data were analyzed by Langmuir, Freundlich, Temkin, Dubinin-Radushkevich, and Toth isotherm models. The results indicated that the Toth and Langmuir models provided the best correlation of the experimental data. The adsorption capacity of peanut husk for the removal of NR was deter...展开更多
This work investigates the start-up characteristics of linear compressors in a refrigeration system through experiment and simulation.Experiments are carried out by a refrigeration test system with a linear compressor...This work investigates the start-up characteristics of linear compressors in a refrigeration system through experiment and simulation.Experiments are carried out by a refrigeration test system with a linear compressor controlled by a LabVIEW platform.A simulation model that considers the nonlinear process of gas force is set up on the basis of Runge-Kutta method for linear compressors.Compared with the experimental results,the simulation errors are within 15%,including the unstable state.The influences of ambient temperature and power frequency on linear compressors are studied through experiments.Unstable phenomena exist at 25℃ ambient temperature compared with the designed ambient temperature of 35℃.The unsteadiness mechanism is analyzed by simulation.Simulation analysis indicated that two sensitive stages of linear compressors,namely,starting to pump and touching top dead center,are unstable.Furthermore,properly increasing equivalent mass (approximately 3%) or spring stiffness doring the design stage can be a practical method to improve the stability of linear compressors.展开更多
文摘为解决低温余热资源过剩与高温用热需求紧缺之间的矛盾,设计了一套基于准二级压缩的高温热泵机组,理论分析循环流程并进行优化设计,采用闪蒸器与回热器组合提高机组性能,开展了机组的性能实验,以制热量、制热COP、[火用]效率、冷凝压力、排气温度为性能指标,在冷凝器出水温度为85~120℃,蒸发器进水温度为50、60、70℃工况下,对机组性能进行分析。实测机组性能与理论计算结果吻合,蒸发器进水温度为49.8℃,冷凝器出水温度为118.1℃,机组制热量可达916.3 k W,制热COP为2.51,[火用]效率为46.3%,机组冷凝压力为1.8 MPa,排气温度为137℃,符合机组安全运行的要求。
文摘目的探究细胞增殖分化的Notch信号通路在曲安奈德治疗裸鼠血管瘤模型过程中的表达情况及其作用机制。方法选取2022年12月—2023年6月深圳市龙岗中心医院18只小鼠。分为Control组、Control+TA for 7 days处理组、Control+TA for 14 days处理组,每组6只,并进行相应给药处理,每3 d记录肿瘤生长状况,利用蛋白质免疫印迹(western blot,WB)和实时荧光定量聚合酶链式反应(real-time quantitative polymerase chain reaction,qPCR)检测糖皮质激素受体α(glucocorticoid receptorα,GRα)、Notch1、表皮生长因子受体(epidermal growth factor receptor,EGRF)和Split多毛增强子(hairy and enhancer of split,HES1)蛋白表达情况,免疫组化观察阳性细胞。结果WB实验结果显示,与Control组相比,Control+TA for 7 days处理组和Control+TA for 14 days处理组中GRα、Notch1和EGFR蛋白表达显著下降,而HES1蛋白显著上升,差异有统计学意义(P<0.05);qPCR实验结果显示,与对照组相比,Control+TA for 7 days处理组和Control+TA for 14 days处理组中GRα、Notch1和HES1蛋白表达显著下降,而EGFR蛋白显著上升,差异有统计学意义(P<0.05);免疫组化结果显示,与Control组相比,Control+TA for 7 days处理组免疫组化和Control+TA for 14 days处理组中GRα、Notch1、HES1和EGFR阳性细胞减少,差异有统计学意义(P<0.05)。结论曲安奈德可使裸鼠模型血管瘤组织GRα、Notch1表达下降,Notch信号通路参与曲安奈德治疗血管瘤的作用过程。
基金the China PostdoctoralScience Foundation (No. 20070420811)the Edu-cation Department of Henan Province in China (No.200510459016)
文摘Adsorption of Neutral Red (NR) onto peanut husk in aqueous solutions was investigated at 295 K. Experiments were carried out as function of pH, adsorbent dosage, contact time, and initial concentration. The equilibrium adsorption data were analyzed by Langmuir, Freundlich, Temkin, Dubinin-Radushkevich, and Toth isotherm models. The results indicated that the Toth and Langmuir models provided the best correlation of the experimental data. The adsorption capacity of peanut husk for the removal of NR was deter...
基金We would like to thank the support from the National Natural Science Foundation of China(No.51576203 and No.51976229)this study is also supported by CAS Key Laboratory of Cryogenics,TIPC(No.CRYOQN201908)Dr.Tang M.S.is supported by Youth Innovation Promotion Association,CAS(No.2018032).
文摘This work investigates the start-up characteristics of linear compressors in a refrigeration system through experiment and simulation.Experiments are carried out by a refrigeration test system with a linear compressor controlled by a LabVIEW platform.A simulation model that considers the nonlinear process of gas force is set up on the basis of Runge-Kutta method for linear compressors.Compared with the experimental results,the simulation errors are within 15%,including the unstable state.The influences of ambient temperature and power frequency on linear compressors are studied through experiments.Unstable phenomena exist at 25℃ ambient temperature compared with the designed ambient temperature of 35℃.The unsteadiness mechanism is analyzed by simulation.Simulation analysis indicated that two sensitive stages of linear compressors,namely,starting to pump and touching top dead center,are unstable.Furthermore,properly increasing equivalent mass (approximately 3%) or spring stiffness doring the design stage can be a practical method to improve the stability of linear compressors.
