目的:评价推拿治疗抽动障碍的有效性和安全性。方法:通过检索中文数据库中国知网、万方数据知识服务平台、维普全文数据库以及英文数据库PubMed、Web of Science、Embase数据库建立之日起至2020年4月13日止所有有关推拿治疗抽动障碍的...目的:评价推拿治疗抽动障碍的有效性和安全性。方法:通过检索中文数据库中国知网、万方数据知识服务平台、维普全文数据库以及英文数据库PubMed、Web of Science、Embase数据库建立之日起至2020年4月13日止所有有关推拿治疗抽动障碍的随机对照试验,经过文献筛选、文献质量评价、发表偏倚评估筛选出所有符合标准的文献,根据疗效指标提取数据,汇总后利用RevMan 5.3软件进行Meta分析。结果:共纳入符合标准的文献15篇,均为随机对照试验,纳入病例共1195例,其中试验组625例,对照组570例。数据分析结果显示,试验组治疗抽动障碍可提高总有效率(P<0.0001)、治愈率(P<0.00001),降低耶鲁综合抽动严重程度量表(Yale Global Tic Severity Scale,YGTSS)评分(P<0.01)、中医证候积分(P<0.0001);共9篇文献报告了不良反应发生情况,试验组与对照组整体不良事件发生率的差异有统计学意义(P<0.00001);漏斗图中线两侧的研究分布不对称,提示存在发表偏倚。结论:对比常规疗法,推拿疗法治疗抽动障碍的整体临床疗效更显著、不良反应发生情况更少、安全性更高。但由于本研究存在局限性,结论仍需更多多中心、大样本、高质量文献来进一步验证。展开更多
Magnesite fine powder, natural silica powder,light-burned magnesia fine powder, silica fume and middle grade magnesia fine powder were used as the starting materials,and silica sol as binder to get high purity lightwe...Magnesite fine powder, natural silica powder,light-burned magnesia fine powder, silica fume and middle grade magnesia fine powder were used as the starting materials,and silica sol as binder to get high purity lightweight spherical forsterite aggregates. The mixture was granulated on a disc pelletizer and then calcined at 1 400 ℃ for 3h. The synthesized spherical forsterite aggregates were added in Mg O based castables with MgO-SiO2-H2O binding system to replace equaldensity high purity common forsterite aggregates. Effect of spherical forsterite aggregates addition on properties of MgO based castables was investigated. The results show that: compared with common aggregates,lightweight spherical forsterite aggregates can improve castables ’flow ability and decrease water addition; addition of spherical aggregates has little effect on cold strength of castables; with the increase of spherical aggregate addition,shrinkage of specimens after drying and heating at intermediate temperatures decreases,but the expansion of specimens after heating at high temperatures increases,bulk density decreases and apparent porosity increases,and thermal conductivity declines.展开更多
介绍多模态理论的相关概念。阐述将多模态理论应用于初中英语阅读教学的优势,即最大限度地实现“以学生为中心”的新课改要求,有利于学生更好地阅读与理解文本,创建相对真实的语言环境。以How I Learned to Learn English?和Students Wh...介绍多模态理论的相关概念。阐述将多模态理论应用于初中英语阅读教学的优势,即最大限度地实现“以学生为中心”的新课改要求,有利于学生更好地阅读与理解文本,创建相对真实的语言环境。以How I Learned to Learn English?和Students Who Volunteer阅读课文为例,从情境模态、手段模态、互动模态和训练模态四个方面探究多模态理论视角下初中英语阅读教学的策略。展开更多
文摘目的:评价推拿治疗抽动障碍的有效性和安全性。方法:通过检索中文数据库中国知网、万方数据知识服务平台、维普全文数据库以及英文数据库PubMed、Web of Science、Embase数据库建立之日起至2020年4月13日止所有有关推拿治疗抽动障碍的随机对照试验,经过文献筛选、文献质量评价、发表偏倚评估筛选出所有符合标准的文献,根据疗效指标提取数据,汇总后利用RevMan 5.3软件进行Meta分析。结果:共纳入符合标准的文献15篇,均为随机对照试验,纳入病例共1195例,其中试验组625例,对照组570例。数据分析结果显示,试验组治疗抽动障碍可提高总有效率(P<0.0001)、治愈率(P<0.00001),降低耶鲁综合抽动严重程度量表(Yale Global Tic Severity Scale,YGTSS)评分(P<0.01)、中医证候积分(P<0.0001);共9篇文献报告了不良反应发生情况,试验组与对照组整体不良事件发生率的差异有统计学意义(P<0.00001);漏斗图中线两侧的研究分布不对称,提示存在发表偏倚。结论:对比常规疗法,推拿疗法治疗抽动障碍的整体临床疗效更显著、不良反应发生情况更少、安全性更高。但由于本研究存在局限性,结论仍需更多多中心、大样本、高质量文献来进一步验证。
文摘【目的】筛选不同非生物胁迫下芒根组织中稳定表达的内参基因,并为调控芒根组织中基因表达提供理论依据。【方法】以芒(Miscanthus sinensis)根组织为试验材料,通过实时荧光定量PCR技术检测12个候选内参基因在不同非生物胁迫环境(干旱、盐、镉、铬和砷)下的表达情况,并运用geNorm、BestKeeper、NormFinder和RefFinder软件分析它们在芒根组织中的稳定性。【结果】在不同的非生物环境胁迫条件下,最稳定的内参基因各不相同。12个内参基因表达稳定性由高到低排序为:Unigene26576,Unigene33024,Sb02g041180,eIF4A,ACTIN,GAPDH,Unigene33312,Sb09g019750,PP2A,SAMDC,18S rRNA,SAMS。其中在干旱胁迫条件下,Sb02g041180和ACTIN基因最稳定;在盐胁迫和砷胁迫处理下最稳定的内参基因分别是Sb09g019750和Unigene26576、Sb09g019750和PP2A;镉和铬胁迫下最稳定的内参基因分别为Unigene26576和PP2A、Sb09g019750和Unigene33312。【结论】Unigene26576和Unigene33024最适合作为研究芒根组织非生物胁迫的内参基因,而18S r RNA和SAMS最不适合作为内参基因。鉴定了候选基因在芒根组织中的稳定性,对进一步研究芒非生物胁迫下基因表达奠定了基础。
文摘Magnesite fine powder, natural silica powder,light-burned magnesia fine powder, silica fume and middle grade magnesia fine powder were used as the starting materials,and silica sol as binder to get high purity lightweight spherical forsterite aggregates. The mixture was granulated on a disc pelletizer and then calcined at 1 400 ℃ for 3h. The synthesized spherical forsterite aggregates were added in Mg O based castables with MgO-SiO2-H2O binding system to replace equaldensity high purity common forsterite aggregates. Effect of spherical forsterite aggregates addition on properties of MgO based castables was investigated. The results show that: compared with common aggregates,lightweight spherical forsterite aggregates can improve castables ’flow ability and decrease water addition; addition of spherical aggregates has little effect on cold strength of castables; with the increase of spherical aggregate addition,shrinkage of specimens after drying and heating at intermediate temperatures decreases,but the expansion of specimens after heating at high temperatures increases,bulk density decreases and apparent porosity increases,and thermal conductivity declines.
文摘介绍多模态理论的相关概念。阐述将多模态理论应用于初中英语阅读教学的优势,即最大限度地实现“以学生为中心”的新课改要求,有利于学生更好地阅读与理解文本,创建相对真实的语言环境。以How I Learned to Learn English?和Students Who Volunteer阅读课文为例,从情境模态、手段模态、互动模态和训练模态四个方面探究多模态理论视角下初中英语阅读教学的策略。
