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自体血回收在剖宫产术中应用的安全性、可行性研究 被引量:6
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作者 唐荣瑜 刘琼 +1 位作者 赖新华 刘娇兰 《中国医学创新》 CAS 2018年第21期128-131,共4页
目的:探讨自体血回收在剖宫产术中的应用效果。方法:选取本院2017年1月-2018年1月收治的择期剖宫产分娩的前置胎盘患者22例作为研究对象。观察患者自体血回收前后血流动力学;采用速率散射比浊法测定血清免疫球蛋白Ig G、Ig M、Ig A水平... 目的:探讨自体血回收在剖宫产术中的应用效果。方法:选取本院2017年1月-2018年1月收治的择期剖宫产分娩的前置胎盘患者22例作为研究对象。观察患者自体血回收前后血流动力学;采用速率散射比浊法测定血清免疫球蛋白Ig G、Ig M、Ig A水平,单向免疫扩散法测定补体C3、C4水平;采用流式细胞仪法检测T细胞亚群CD8^+、CD4^+、CD4^+/CD8^+水平。结果:回收后患者的血清Ig G、Ig A、Ig M、C3、C4水平与回收前比较,差异均无统计学意义(P>0.05);CD4^+、CD8^+、CD4^+/CD8^+水平与回收前比较,差异均无统计学意义(P>0.05);血氧饱和度、舒张压、收缩压、心率与回收前比较,差异均无统计学意义(P>0.05)。结论:自体血回收不会影响T细胞亚群平衡与体液免疫,并不会对血流动力学产生影响。 展开更多
关键词 回收式自体输血 剖宫产 血流动力 免疫
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Statistical Analysis of the Dynamic Parameters of Silty Clay in the Beijing Area
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作者 Shi Chunhua Lu Yuejun +1 位作者 Peng Yanju tang rongyu 《Earthquake Research in China》 2010年第1期117-127,共11页
Soil dynamic parameters,including dynamic shear modulus ratio and damping ratio,have important effects on the results of layered soil earthquake response. In this paper,the mean parameter values of silty clay in diffe... Soil dynamic parameters,including dynamic shear modulus ratio and damping ratio,have important effects on the results of layered soil earthquake response. In this paper,the mean parameter values of silty clay in different depths are obtained after statistical analysis of the experimental soil dynamic data from 20 recent site seismic safety evaluation reports in the Beijing area. Furthermore,based on two typical engineering sites,the influence of four different soil dynamic parameters,the statistic mean values,experimental values, values recommended by Yuan Xiaoming,and the values recommended in the code for seismic safety evaluation of engineering sites( DB001-94) are analyzed. The result shows that mean statistical values are applicable to seismic safety evaluation work in the Beijing area,especially for some inter-layered silty clays whose undisturbed soil samples are hard to obtain. 展开更多
关键词 北京地区 粉质粘土 动力参数 统计分析 地震安全性评价 统计平均值 土层地震反应 工程场地
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Soft Soil Site Characterization on the Coast of Yantai and Its Effect on Ground Motion Parameters
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作者 Lü Yuejun tang rongyu Peng Yanju 《Earthquake Research in China》 2005年第2期116-124,共9页
According to the Chinese GB50011-2001 code and the recommended provisions of FEMA-NEHRP and EUROCODE 8, by using shear wave velocity and borehole data, the site classification is evaluated for a typical soft soil site... According to the Chinese GB50011-2001 code and the recommended provisions of FEMA-NEHRP and EUROCODE 8, by using shear wave velocity and borehole data, the site classification is evaluated for a typical soft soil site on the Yantai seacoast. The site seismic ground motion effect is analyzed and the influence of the coastal soil on design ground motion parameters is discussed. The results show that the brief site classification can not represent the real conditions of a soft soil site; the soft soil on the coast has a remarkable impact on the magnitude and spectrum of ground motion acceleration. The magnification on peak acceleration is bigger, however, due to the nonlinear deformation of the soil. The magnification is reduced nonlinearly with the increase of input ground motion; the spectrum is broadened and the characteristic period elongated on the soft soil site. 展开更多
关键词 地震 烟台市 剪切波 地位分级
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Neuromorphic transcutaneous electrical nerve stimulation(nTENS)induces efficient tactile-related cortical networks in forearm amputees
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作者 LIU YaFei LI Bo +8 位作者 XI PengCheng LV XiaoDan ZHANG Lin LIU ZhiQiang HUANG Qiang tang rongyu HE JiPing CHEN LuYao LANG YiRan 《Science China(Technological Sciences)》 SCIE EI CAS CSCD 2023年第5期1451-1460,共10页
Conventional transcutaneous electrical nerve stimulation(cTENS),which uses a modulated square waveform as stimuli,has been generally used in testing and eliciting artificial tactile perception in forearm amputees.Howe... Conventional transcutaneous electrical nerve stimulation(cTENS),which uses a modulated square waveform as stimuli,has been generally used in testing and eliciting artificial tactile perception in forearm amputees.However,a novel neuromorphic TENS(nTENS)model based on neural signals has been largely ignored.In this study,we further explore the effect of nTENS patterns to elicit tactile perception in forearm amputees.Four forearm amputees were recruited to test discriminate tactile perception elicited by different TENS patterns with electroencephalography(EEG)recording at the following four stimulated sites:the index finger and the little finger on both phantom and real sides.Finally,we compared the results of cortical networks in six frequency bands at different stimulated sites between forearm amputees and able-bodied subjects.Behavioral results suggested that n TENS patterns required a lower electric charge at each stimulated site than cTENS patterns.And forearm amputees required a higher intensity in each TENS pattern than able-bodied subjects.Moreover,amputees showed a lower clustering coefficient(aCP),global efficiency(aEG),local efficiency(aEL),and a longer path length(aLP)than able-bodied subjects in all six frequency bands when stimulation was accessed.Specifically,the SMU pattern showed a higher functional network efficiency in real fingers than at phantom sites in theta,alpha,and high gamma bands.This study highlighted the characteristics of n TENS patterns in eliciting tactile perception among forearm amputees,which provided insights into evaluating the neural mechanism of tactile information processing in forearm amputees and building tactile perceptual systems for sensory rehabilitation. 展开更多
关键词 nTENS EEG cortical functional network tactile perception forearm amputees
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女性膀胱出口梗阻的超声影像尿动力学检查特点分析 被引量:6
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作者 唐蓉玉 肖宁 +4 位作者 赵划晟 陈莲花 唐琦 林玮键 王建峰 《中华泌尿外科杂志》 CAS CSCD 北大核心 2021年第5期385-387,共3页
本研究通过超声影像尿动力学检查(SVUDS),观察患者充盈期及排尿期尿道和周围盆底结构的改变,诊断26例女性膀胱出口梗阻(FBOO)。其中13例盆腔器官脱垂,排尿期可见尿道成角畸形;5例失调性排尿,排尿期中段尿道开放不佳;4例尿道狭窄,排尿期... 本研究通过超声影像尿动力学检查(SVUDS),观察患者充盈期及排尿期尿道和周围盆底结构的改变,诊断26例女性膀胱出口梗阻(FBOO)。其中13例盆腔器官脱垂,排尿期可见尿道成角畸形;5例失调性排尿,排尿期中段尿道开放不佳;4例尿道狭窄,排尿期梗阻近端扩张,梗阻部位无松弛表现;1例原发性膀胱颈梗阻,排尿期膀胱颈开放不完全;3例特发性膀胱出口梗阻,排尿期膀胱颈及尿道外括约肌开放良好。SVUDS有助于明确FBOO的病因,提高诊断效果。 展开更多
关键词 尿道梗阻 膀胱 影像尿动力学 女性 超声
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Investigation of flexible electrodes modified by TiN,Pt black and IrO_x 被引量:4
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作者 LI XiaoQian PEI WeiHua +4 位作者 tang rongyu GUI Qiang GUO Kai WANG Yu CHEN HongDa 《Science China(Technological Sciences)》 SCIE EI CAS 2011年第9期2305-2309,共5页
TiN,platinum (Pt) black and iridium oxide are introduced to the stimulating sites to improve the performance of the flexible electrode.Low temperature process is used to fabricate the modifying films.TiN is coated on ... TiN,platinum (Pt) black and iridium oxide are introduced to the stimulating sites to improve the performance of the flexible electrode.Low temperature process is used to fabricate the modifying films.TiN is coated on the gold sites by magnetron sputtering while platinum black and iridium oxide are coated by electroplating and electrodeposition,respectively.The im-pedance of the electrode decreases dramatically after modification.The combined analysis of surface morphology and cyclic voltammograms (CV) in phosphate buffer saline (PBS) solution indicates that the modified electrode sites have larger elec-trode-electrolyte capacitance and smaller faradic resistance than unmodified sites,thus they have smaller electrochemical im-pedances. 展开更多
关键词 修饰电极 修改 铂黑 黑色 氧化物涂层 电化学阻抗 磷酸盐缓冲液
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A composite insulation structure for silicon-based planar neuroprobes 被引量:2
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作者 ZHAO Hui PEI WeiHua +4 位作者 CHEN SanYuan GUI Qiang tang rongyu GUO Kai CHEN HongDa 《Science China(Technological Sciences)》 SCIE EI CAS 2012年第9期2436-2440,共5页
Silicon-based planar neuroprobes are composed of silicon substrate,conducting layer,and insulation layers of SiO 2 or SiN membrane.The insulation layer is very important because it affects many key parameters of neupr... Silicon-based planar neuroprobes are composed of silicon substrate,conducting layer,and insulation layers of SiO 2 or SiN membrane.The insulation layer is very important because it affects many key parameters of neuprobes,like impedance,SNR(signal noise ratio),reliability,etc.Monolayer membrane of SiO 2 or SiN are not good choices for insulation layer,since defects and residual stress in these layers can induce bad passivation.In this paper a composite insulation structure is studied,with thermal SiO 2 as the lower insulation layer and with multilayer membrane composed of PECVD SiO 2 and SiN as the upper insulation layer.This structure not only solves the problem of residual stress but also ensures a good probe passivation.So it's a good choice for insulation layer of neuroprobes. 展开更多
关键词 复合保温结构 绝缘硅 平面 SIO2 基础 PECVD法 残余应力 绝缘层
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慢病毒介导的Aurora A沉默对耐阿霉素人膀胱癌细胞凋亡的影响及机制
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作者 肖宁 林玮键 +4 位作者 唐琦 唐蓉玉 朱胜 郭广荣 龙永福 《国际泌尿系统杂志》 2021年第6期981-984,共4页
目的探讨Aurora A在人膀胱癌细胞耐阿霉素(ADM)形成机制中的作用及影响。方法采用ADM浓度梯度递增诱导法建立ADM人膀胱癌T24细胞株(T24/ADM),MTT法检测不同浓度ADM(1μg/mL和2μg/mL)对T24和T24/ADM细胞的毒性作用,分别构建转染Aurora A... 目的探讨Aurora A在人膀胱癌细胞耐阿霉素(ADM)形成机制中的作用及影响。方法采用ADM浓度梯度递增诱导法建立ADM人膀胱癌T24细胞株(T24/ADM),MTT法检测不同浓度ADM(1μg/mL和2μg/mL)对T24和T24/ADM细胞的毒性作用,分别构建转染Aurora A RNAi慢病毒和空载体的T24/ADM细胞(T24/ADM/KD和T24/ADM/NC),2μg/mL阿霉素分别处理T24/ADM、T24/ADM/NC和T24/ADM/KD细胞24 h,Annexin V-FITC/PI和Western blot分别检测各组细胞凋亡率和MRP-1、Bcl-2蛋白表达水平。结果随着ADM浓度增加(2μg/mL ADM处理),T24/ADM细胞耐ADM的细胞毒性作用(22.8±2.0%)较T24细胞(52.5±11.6%)更加明显(P=0.035)。2μg/mL ADM作用于T24/ADM、T24/ADM/NC和T24/ADM/KD细胞24 h后,Annexin V-PE检测各组细胞的凋亡率分别为(6.61±0.44)%、(6.76±0.39)%和(24.43±1.77)%,T24/ADM和T24/ADM/NC细胞间的凋亡率比较,差异无统计学意义(P=0.88);T24/ADM/KD细胞的凋亡率较T24/ADM和T24/ADM/NC细胞显著增加(P<0.01)。2μg/mL ADM作用于T24/ADM、T24/ADM/NC和T24/ADM/KD细胞24 h后,Western blot检测显示T24/ADM/KD细胞的MRP-1和Bcl-2蛋白表达水平均低于T24/ADM和T24/ADM/NC细胞(P<0.05);T24/ADM与T24/ADM/NC细胞的MRP-1(P=0.92)和Bcl-2(P=0.31)蛋白表达水平比较,差异无统计学意义(P=0.31)。结论Aurora A可能通过调控MRP-1和Bcl-2的表达,影响T24/ADM细胞的凋亡和对阿霉素的耐药性,其在膀胱癌多药耐药的形成中可能发挥着重要作用。 展开更多
关键词 膀胱肿瘤 细胞系 Aurora A 阿霉素
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