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探究同步放化疗对中晚期食管癌患者免疫功能的影响 被引量:1
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作者 邰璐 刘永新 《智慧健康》 2019年第29期104-105,124,共3页
目的探究同步放化疗对中晚期食管癌患者免疫功能的影响。方法选取2014年1月至2018年12月期间我院收治的60例中晚期食管癌患者,按治疗方案的区别分为实验组和对照组,每组各30例。对照组采用放射治疗联合对症支持治疗的方法,实验组则采取... 目的探究同步放化疗对中晚期食管癌患者免疫功能的影响。方法选取2014年1月至2018年12月期间我院收治的60例中晚期食管癌患者,按治疗方案的区别分为实验组和对照组,每组各30例。对照组采用放射治疗联合对症支持治疗的方法,实验组则采取同步放化疗进行治疗。通过对两组患者治疗前及治疗后6个月的血清免疫球蛋白A(IgA)、免疫球蛋白M(IgM)及免疫球蛋白G(IgG)的水平变化情况进行统计分析,从而探究其免疫功能的恢复情况。结果治疗前,两组患者各项血清免疫球蛋白的水平差异无统计学意义(P>0.05);治疗后,实验组患者血清免疫球蛋白A(IgA)、免疫球蛋白M(IgM)及免疫球蛋白G(IgG)的水平均明显高于同期对照组患者的相应指标,且组间及组内差异均具有统计学意义(P<0.05)。结论同步放化疗可有效恢复中晚期食管癌患者的免疫功能,从而提高临床治疗效果,因此可尝试将该治疗方式应用于中晚期食管癌患者的治疗当中。 展开更多
关键词 同步放化疗 中晚期食管癌 免疫功能 影响
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Comparison between modified lateral supraorbital approach and pterional approach in the surgical treatment of middle cerebral artery aneurysms 被引量:6
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作者 Zhouqing Chen Xiaoou Sun +6 位作者 tai lu Zhengyang lu Ming Jiang Chongshun Zhao Wanchun You Yun Zhu Zhong Wang 《Chinese Neurosurgical Journal》 CSCD 2018年第1期1-6,共6页
Background:The Middle cerebral artery (MCA) aneurysm is a common type of craniocerebral aneurysm that is prone to rupture and high mortality. The classic surgical approaches are the Pterional approach and the Lateral ... Background:The Middle cerebral artery (MCA) aneurysm is a common type of craniocerebral aneurysm that is prone to rupture and high mortality. The classic surgical approaches are the Pterional approach and the Lateral Supraorbital (LSO) approach, but there are shortcomings. Methods:This study retrospectively analyzed clinical and imaging data from 181 patients with MCA aneurysm clipping in the Department of Neurosurgery, First Affiliated Hospital of Soochow University between 2011 and 2017. Statistical analysis using parametric and nonparametric tests showed that P values below 0.05 were considered statistically significant. Results: The preoperative GCS score (P=0.003), Hunt-Hess scale (P < 0.001) and the operating habits of the surgeon (P < 0.001) affected the surgeon to choose a surgical approach. The choice of two surgical methods on the operation time (P < 0.001), skin incision (P < 0.001), complications (P=0.026), tracheotomy (P=0.014), prognosis (P=0.002) were significantly different. Different surgical approaches (P=0.002), Hunt-Hess scale (P <0.001), GCS scale (P < 0.001), GCS sorse (P < 0.001), skin incision (P=0.031) and complications (P < 0.001) are closely related to the prognosis of patients. Conclusions: Modified LSO approach provides another surgical approach for MCA aneurysm clipping, while avoiding the drawbacks of the LSO approach in the clipping of MCA distal aneurysm. 展开更多
关键词 ANEURYSM CLIPPING Middle cerebral artery ANEURYSMS MODIFIED LATERAL supraorbital APPROACH LATERAL supraorbital APPROACH Pterional APPROACH
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