Dear editor,With the spread of prostate-specific antigen(PSA)screening,an increasing number of early-stage prostate cancers have been diagnosed recently,although many patients are still diagnosed in the advanced stage...Dear editor,With the spread of prostate-specific antigen(PSA)screening,an increasing number of early-stage prostate cancers have been diagnosed recently,although many patients are still diagnosed in the advanced stage[1].Although most prostate cancers with metastatic lesions respond to initial androgen ablation therapy,responders ultimately develop progressive disease due to hormone-refractory cancer.展开更多
文摘Dear editor,With the spread of prostate-specific antigen(PSA)screening,an increasing number of early-stage prostate cancers have been diagnosed recently,although many patients are still diagnosed in the advanced stage[1].Although most prostate cancers with metastatic lesions respond to initial androgen ablation therapy,responders ultimately develop progressive disease due to hormone-refractory cancer.