We presented a 20-year-old patient with Crohn's disease (CD). Colonoscopy revealed longitudinal ulceratlon in the terminal ileum and rectal aphtoid ulcers, After treatment with mesalamine and total parenteral nutr...We presented a 20-year-old patient with Crohn's disease (CD). Colonoscopy revealed longitudinal ulceratlon in the terminal ileum and rectal aphtoid ulcers, After treatment with mesalamine and total parenteral nutrition, repeat colonoscopy revealed a granular elevated area in the terminal ileum, which appeared as an irregular dome-like elevation with irregularly arranged vill on magnifying endoscopy. Biopsy specimens taken from the region showed microgranulomas and lymphoid hyperplasia, Scanning electron microscopy revealed the presence of M cells, conthming that the area corresponded to Peyer's patches. Peyer's patches by magnifying endoscopy and electron microscopy may provide insights into the pathogenesis oF CD.展开更多
文摘We presented a 20-year-old patient with Crohn's disease (CD). Colonoscopy revealed longitudinal ulceratlon in the terminal ileum and rectal aphtoid ulcers, After treatment with mesalamine and total parenteral nutrition, repeat colonoscopy revealed a granular elevated area in the terminal ileum, which appeared as an irregular dome-like elevation with irregularly arranged vill on magnifying endoscopy. Biopsy specimens taken from the region showed microgranulomas and lymphoid hyperplasia, Scanning electron microscopy revealed the presence of M cells, conthming that the area corresponded to Peyer's patches. Peyer's patches by magnifying endoscopy and electron microscopy may provide insights into the pathogenesis oF CD.
