A 72-year-old woman with a sigmoid colon cancer and a synchronous colorectal liver metastasis(CRLM),which involved the right hepatic vein(RHV)and the inferior vena cava(IVC),was referred to our hospital.The metastatic...A 72-year-old woman with a sigmoid colon cancer and a synchronous colorectal liver metastasis(CRLM),which involved the right hepatic vein(RHV)and the inferior vena cava(IVC),was referred to our hospital.The metastatic lesion was diagnosed as initially unresectable because of its invasion into the confluence of the RHV and IVC.After she had undergone laparoscopic sigmoidectomy for the original tumor,she consequently had 3 courses of modified 5-fluorouracil,leucovorin,and oxaliplatin(m FOLFOX6)plus cetuximab.Computed tomography revealed a partial response,and the confluence of the RHV and IVC got free from cancer invasion.After 3 additional courses of m FOLFOX6 plus cetuximab,preoperative percutaneous transhepatic portal vein embolization(PTPE)was performed to secure the future remnant liver volume.Finally,a right hemihepatectomy was performed.The postoperative course was uneventful.The patient was discharged from the hospital on postoperative day 13.She had neither local recurrence nor distant metastasis 18 mo after the last surgical intervention.This multidisciplinary strategy,consisting of conversion chemotherapy using FOLFOX plus cetuximab and PTPE,could contribute in facilitating curative hepatic resection for initially unresectable CRLM.展开更多
In recent years,accurate Gaussian noise removal has attracted considerable attention for mobile applications,as in smart phones.Accurate conventional denoising methods have the potential ability to improve denoising p...In recent years,accurate Gaussian noise removal has attracted considerable attention for mobile applications,as in smart phones.Accurate conventional denoising methods have the potential ability to improve denoising performance with no additional time.Therefore,we propose a rapid post-processing method for Gaussian noise removal in this paper.Block matching and 3D filtering and weighted nuclear norm minimization are utilized to suppress noise.Although these nonlocal image denoising methods have quantitatively high performance,some fine image details are lacking due to the loss of high frequency information.To tackle this problem,an improvement to the pioneering RAISR approach(rapid and accurate image super-resolution),is applied to rapidly post-process the denoised image.It gives performance comparable to state-of-the-art super-resolution techniques at low computational cost,preserving important image structures well.Our modification is to reduce the hash classes for the patches extracted from the denoised image and the pixels from the ground truth to 18 filters by two improvements:geometric conversion and reduction of the strength classes.In addition,following RAISR,the census transform is exploited by blending the image processed by noise removal methods with the filtered one to achieve artifact-free results.Experimental results demonstrate that higher quality and more pleasant visual results can be achieved than by other methods,efficiently and with low memory requirements.展开更多
文摘A 72-year-old woman with a sigmoid colon cancer and a synchronous colorectal liver metastasis(CRLM),which involved the right hepatic vein(RHV)and the inferior vena cava(IVC),was referred to our hospital.The metastatic lesion was diagnosed as initially unresectable because of its invasion into the confluence of the RHV and IVC.After she had undergone laparoscopic sigmoidectomy for the original tumor,she consequently had 3 courses of modified 5-fluorouracil,leucovorin,and oxaliplatin(m FOLFOX6)plus cetuximab.Computed tomography revealed a partial response,and the confluence of the RHV and IVC got free from cancer invasion.After 3 additional courses of m FOLFOX6 plus cetuximab,preoperative percutaneous transhepatic portal vein embolization(PTPE)was performed to secure the future remnant liver volume.Finally,a right hemihepatectomy was performed.The postoperative course was uneventful.The patient was discharged from the hospital on postoperative day 13.She had neither local recurrence nor distant metastasis 18 mo after the last surgical intervention.This multidisciplinary strategy,consisting of conversion chemotherapy using FOLFOX plus cetuximab and PTPE,could contribute in facilitating curative hepatic resection for initially unresectable CRLM.
基金This research was funded by the National Natural Science Foundation of China under Grant Nos.61873117,62007017,61773244,61772253,and 61771231。
文摘In recent years,accurate Gaussian noise removal has attracted considerable attention for mobile applications,as in smart phones.Accurate conventional denoising methods have the potential ability to improve denoising performance with no additional time.Therefore,we propose a rapid post-processing method for Gaussian noise removal in this paper.Block matching and 3D filtering and weighted nuclear norm minimization are utilized to suppress noise.Although these nonlocal image denoising methods have quantitatively high performance,some fine image details are lacking due to the loss of high frequency information.To tackle this problem,an improvement to the pioneering RAISR approach(rapid and accurate image super-resolution),is applied to rapidly post-process the denoised image.It gives performance comparable to state-of-the-art super-resolution techniques at low computational cost,preserving important image structures well.Our modification is to reduce the hash classes for the patches extracted from the denoised image and the pixels from the ground truth to 18 filters by two improvements:geometric conversion and reduction of the strength classes.In addition,following RAISR,the census transform is exploited by blending the image processed by noise removal methods with the filtered one to achieve artifact-free results.Experimental results demonstrate that higher quality and more pleasant visual results can be achieved than by other methods,efficiently and with low memory requirements.
