目的分析影响单囊胚冻融移植周期活产结局的相关因素,探讨单囊胚移植的可行性。方法回顾性分析2012年1月至2016年12月在本中心接受单囊胚冻融移植的共2593个周期的临床资料,根据妊娠结局分为活产组(1058个周期)和非活产组(1535个周期),...目的分析影响单囊胚冻融移植周期活产结局的相关因素,探讨单囊胚移植的可行性。方法回顾性分析2012年1月至2016年12月在本中心接受单囊胚冻融移植的共2593个周期的临床资料,根据妊娠结局分为活产组(1058个周期)和非活产组(1535个周期),同时进行年龄(<35岁、35~39岁、≥40岁)和囊胚质量/发育速度分层分析,研究影响单囊胚冻融移植活产结局的相关因素。结果(1)活产组移植年龄中位数显著小于非活产组(31岁vs.32岁),移植日内膜厚度(9.2 mm vs.9.0 mm)和优质囊胚率(72.5%vs.62.5%)则显著高于非活产组(P<0.05)。(2)不同女性年龄组内随着内细胞团和滋养层细胞评分等级降低活产率降低,差异有统计学意义(P<0.05),但并未发现不同囊胚腔扩张等级对活产率的影响(P>0.05);对于年龄<35岁和35~39岁患者,D5囊胚移植较D6/D7囊胚移植具有更高的活产率,差异有统计学意义(P<0.05)。(3)年龄<35岁的女性单囊胚移植活产率高于35岁以上具有相同囊胚评级的患者,并且年龄<35岁BB及以上评级的单囊胚移植可获得>45%的活产率。结论女方年龄、囊胚质量及囊胚发育速度对单囊胚冻融移植周期活产结局有显著影响。复苏周期中35岁以下女性移植单个优质囊胚的活产率可达45%以上,提示单囊胚移植可行。制定个体化胚胎选择策略是确保单胚胎移植成功率的关键。展开更多
Objective To study the salivation features depending on gender identity of patients currently is of great interest because homeostasis in the oral cavity may change under the influence of social lifestyle,psychology a...Objective To study the salivation features depending on gender identity of patients currently is of great interest because homeostasis in the oral cavity may change under the influence of social lifestyle,psychology and physiology of patient's gender. Given this,the study of the most important biological environment of the organism is relevant in different physiological stages of life. The aim of our study is to evaluate the characteristics of salivation depending on gender and sexual identity of patients,taking into account age and physiological periods of life. Methods One hundred and seventy-five people,115 women and 60 men aged from 18 up to 75 years participated in the research conducted by us. Carried out dental inspection of patients,carried out questioning according to Fox's test for identification of existence or lack of a kserostomiya and also carried out collecting the mixed saliva at rest. Results Our results from people requested dental care revealed that there were more women with xerostomia than men and their symptom intensity was stronger. The frequency of manifestation of xerostomia was associated with physiological periods of their lives,with greater emotionality and exposure to stresses,and also with long medication intake. Men were less analyzing the state of their health and noted better stress resistance to a different life situations. Xerostomia was found in them in the case of comorbidity,excessive consumption of sugar rich food and drinks,and less frequently as a result of stress. Conclusion For all patients suffering from false xerostomia were recommended the use of a moisturizing line "Kin Hydrate"to relieve the state of dryness in the mouth,as well as more thorough individual hygiene and intensive supervision by a dentist. The data collected require more careful attention of doctors to prevention of dental diseases,especially in vulnerable physiological periods of life,and changing lifestyle factors and social roles of men and women in today's society must be taken into account in the formation of prevention,treatment and dispensary observation at different levels of organization in the health care system.展开更多
文摘目的分析影响单囊胚冻融移植周期活产结局的相关因素,探讨单囊胚移植的可行性。方法回顾性分析2012年1月至2016年12月在本中心接受单囊胚冻融移植的共2593个周期的临床资料,根据妊娠结局分为活产组(1058个周期)和非活产组(1535个周期),同时进行年龄(<35岁、35~39岁、≥40岁)和囊胚质量/发育速度分层分析,研究影响单囊胚冻融移植活产结局的相关因素。结果(1)活产组移植年龄中位数显著小于非活产组(31岁vs.32岁),移植日内膜厚度(9.2 mm vs.9.0 mm)和优质囊胚率(72.5%vs.62.5%)则显著高于非活产组(P<0.05)。(2)不同女性年龄组内随着内细胞团和滋养层细胞评分等级降低活产率降低,差异有统计学意义(P<0.05),但并未发现不同囊胚腔扩张等级对活产率的影响(P>0.05);对于年龄<35岁和35~39岁患者,D5囊胚移植较D6/D7囊胚移植具有更高的活产率,差异有统计学意义(P<0.05)。(3)年龄<35岁的女性单囊胚移植活产率高于35岁以上具有相同囊胚评级的患者,并且年龄<35岁BB及以上评级的单囊胚移植可获得>45%的活产率。结论女方年龄、囊胚质量及囊胚发育速度对单囊胚冻融移植周期活产结局有显著影响。复苏周期中35岁以下女性移植单个优质囊胚的活产率可达45%以上,提示单囊胚移植可行。制定个体化胚胎选择策略是确保单胚胎移植成功率的关键。
文摘Objective To study the salivation features depending on gender identity of patients currently is of great interest because homeostasis in the oral cavity may change under the influence of social lifestyle,psychology and physiology of patient's gender. Given this,the study of the most important biological environment of the organism is relevant in different physiological stages of life. The aim of our study is to evaluate the characteristics of salivation depending on gender and sexual identity of patients,taking into account age and physiological periods of life. Methods One hundred and seventy-five people,115 women and 60 men aged from 18 up to 75 years participated in the research conducted by us. Carried out dental inspection of patients,carried out questioning according to Fox's test for identification of existence or lack of a kserostomiya and also carried out collecting the mixed saliva at rest. Results Our results from people requested dental care revealed that there were more women with xerostomia than men and their symptom intensity was stronger. The frequency of manifestation of xerostomia was associated with physiological periods of their lives,with greater emotionality and exposure to stresses,and also with long medication intake. Men were less analyzing the state of their health and noted better stress resistance to a different life situations. Xerostomia was found in them in the case of comorbidity,excessive consumption of sugar rich food and drinks,and less frequently as a result of stress. Conclusion For all patients suffering from false xerostomia were recommended the use of a moisturizing line "Kin Hydrate"to relieve the state of dryness in the mouth,as well as more thorough individual hygiene and intensive supervision by a dentist. The data collected require more careful attention of doctors to prevention of dental diseases,especially in vulnerable physiological periods of life,and changing lifestyle factors and social roles of men and women in today's society must be taken into account in the formation of prevention,treatment and dispensary observation at different levels of organization in the health care system.
