Objective:To study the effectiveness of Qingre Yangyin Humo prescription in preventing radioaction esophagitis and its effect on the serum radiation damage indexes.Methods:Patients with advanced esophageal cancer who ...Objective:To study the effectiveness of Qingre Yangyin Humo prescription in preventing radioaction esophagitis and its effect on the serum radiation damage indexes.Methods:Patients with advanced esophageal cancer who received radiotherapy in the First Affiliated Hospital of Bengbu Medical College between June 2015 and December 2016 were selected as the research subjects and randomly divided into two groups, the intervention group received Qingre Yangyin Humo prescription during radiotherapy, and the control group received regular intervention during radiotherapy. The incidence of radiation esophagitis within 90 days after radiotherapy was observed, and serum inflammation indexes, oxidative stress indexes and pulmonary fibrosis index were determined before radiotherapy as well as 2 weeks and 4 weeks after radiotherapy.Results: After radiotherapy, serum TNF-α, IL-1β, IL-6, IL-8, MDA, 8-OHdG, MMP9, TGF-β1 and ACE levels of both groups were significantly higher than those before radiotherapy while GPX1, T-SOD and Mn-SOD levels were significantly lower than those before radiotherapy, and serum TNF-α, IL-1β, IL-6, IL-8, MDA, 8-OHdG, MMP9, TGF-β1 and ACE levels of intervention group were significantly lower than those of control group while GPX1, T-SOD and Mn-SOD levels were significantly higher than those of control group.Conclusion:Qingre Yangyin Humo prescription can prevent the occurrence of radiation esophagitis and reduce radiation damage during radiotherapy.展开更多
目的:探究分类评估式心理护理联合康复训练在改善慢阻肺患者肺功能指标中的效果。方法:选取萍乡市第二人民医院呼吸与危重症医学科2018年11月—2021年11月收治的92例慢阻肺患者。以计算机完全随机分组法将其分为试验组(n=46)、参照组(n=...目的:探究分类评估式心理护理联合康复训练在改善慢阻肺患者肺功能指标中的效果。方法:选取萍乡市第二人民医院呼吸与危重症医学科2018年11月—2021年11月收治的92例慢阻肺患者。以计算机完全随机分组法将其分为试验组(n=46)、参照组(n=46)。参照组行康复训练,试验组在参照组的基础上加用分类评估式心理护理。对比两组负性情绪[症状自评量表(symptom checklist 90,SCL-90)]、肺功能指标、生活质量[健康调查简表(the MOS item short form health survey,SF-36)]。结果:干预后,试验组负性情绪均低于参照组,差异均有统计学意义(P<0.05);试验组肺功能指标均优于参照组,差异均有统计学意义(P<0.05);试验组生活质量评分均高于参照组,差异均有统计学意义(P<0.05)。结论:分类评估式心理护理联合康复训练可以降低患者的负性情绪,改善患者的肺功能指标,并提高患者的生活质量。展开更多
文摘Objective:To study the effectiveness of Qingre Yangyin Humo prescription in preventing radioaction esophagitis and its effect on the serum radiation damage indexes.Methods:Patients with advanced esophageal cancer who received radiotherapy in the First Affiliated Hospital of Bengbu Medical College between June 2015 and December 2016 were selected as the research subjects and randomly divided into two groups, the intervention group received Qingre Yangyin Humo prescription during radiotherapy, and the control group received regular intervention during radiotherapy. The incidence of radiation esophagitis within 90 days after radiotherapy was observed, and serum inflammation indexes, oxidative stress indexes and pulmonary fibrosis index were determined before radiotherapy as well as 2 weeks and 4 weeks after radiotherapy.Results: After radiotherapy, serum TNF-α, IL-1β, IL-6, IL-8, MDA, 8-OHdG, MMP9, TGF-β1 and ACE levels of both groups were significantly higher than those before radiotherapy while GPX1, T-SOD and Mn-SOD levels were significantly lower than those before radiotherapy, and serum TNF-α, IL-1β, IL-6, IL-8, MDA, 8-OHdG, MMP9, TGF-β1 and ACE levels of intervention group were significantly lower than those of control group while GPX1, T-SOD and Mn-SOD levels were significantly higher than those of control group.Conclusion:Qingre Yangyin Humo prescription can prevent the occurrence of radiation esophagitis and reduce radiation damage during radiotherapy.
文摘目的:探究分类评估式心理护理联合康复训练在改善慢阻肺患者肺功能指标中的效果。方法:选取萍乡市第二人民医院呼吸与危重症医学科2018年11月—2021年11月收治的92例慢阻肺患者。以计算机完全随机分组法将其分为试验组(n=46)、参照组(n=46)。参照组行康复训练,试验组在参照组的基础上加用分类评估式心理护理。对比两组负性情绪[症状自评量表(symptom checklist 90,SCL-90)]、肺功能指标、生活质量[健康调查简表(the MOS item short form health survey,SF-36)]。结果:干预后,试验组负性情绪均低于参照组,差异均有统计学意义(P<0.05);试验组肺功能指标均优于参照组,差异均有统计学意义(P<0.05);试验组生活质量评分均高于参照组,差异均有统计学意义(P<0.05)。结论:分类评估式心理护理联合康复训练可以降低患者的负性情绪,改善患者的肺功能指标,并提高患者的生活质量。