A new synthesis method of difenoconazole is studied.Difenoconazole is prepared from m-dichlorobenzene by Friedel Crafts reaction,cyclization,bromination,nucleophilic substitution and etherification.The new process imp...A new synthesis method of difenoconazole is studied.Difenoconazole is prepared from m-dichlorobenzene by Friedel Crafts reaction,cyclization,bromination,nucleophilic substitution and etherification.The new process improves the selectivity of the reaction and simplified the pu-rification process.The total yield of this process is 84%,which provides a green and economical synthetic route for industrialization.展开更多
文摘A new synthesis method of difenoconazole is studied.Difenoconazole is prepared from m-dichlorobenzene by Friedel Crafts reaction,cyclization,bromination,nucleophilic substitution and etherification.The new process improves the selectivity of the reaction and simplified the pu-rification process.The total yield of this process is 84%,which provides a green and economical synthetic route for industrialization.
