Imperforate hymen is a rare disorder that is usually discovered at the onset of menstruation. In the literature, secondary closure of the hymen has been reported in 2 cases, both of which occurred subsequent to surgic...Imperforate hymen is a rare disorder that is usually discovered at the onset of menstruation. In the literature, secondary closure of the hymen has been reported in 2 cases, both of which occurred subsequent to surgical procedures that involved the hymen. We report an interesting case of the spontaneous formation of an imperforate hymen during pregnancy in the absence of previous surgical procedures. Electron microscopic findings indicate hymenal tissue reorganization.展开更多
Objective: This study was undertaken to evaluate the role of secondary cytoreduction in patients with recurrent epithelial ovarian cancer. Study design: Secondarily, cytoreduced patients were retrospectively analyzed ...Objective: This study was undertaken to evaluate the role of secondary cytoreduction in patients with recurrent epithelial ovarian cancer. Study design: Secondarily, cytoreduced patients were retrospectively analyzed with respect to the clinicopathologic variables. Results: A total of 64 patients were evaluated in this report. Multivariable analysis revealed 3 factors to be significant: optimal cytoreduction during primary (P = .003, odds ratio [OR]: 0.30; 95%CI: 0.14-0.66), secondary cytoreduction (P = .04, OR: 0.47; 95%CI: 0.22-0.99), and the endometrioid histologic type (P = .005, OR: 0.09; 95%CI: 0.02-0.48). Intrinsic factors of the tumors (grade, stage, age), size, and number of recurrent tumors were nonsignificant. Conclusion: Secondary cytoreductive surgery should be offered in selected recurrent epithelial ovarian cancer patients. Further prospective randomized series are needed to determine specific recommendations.展开更多
文摘Imperforate hymen is a rare disorder that is usually discovered at the onset of menstruation. In the literature, secondary closure of the hymen has been reported in 2 cases, both of which occurred subsequent to surgical procedures that involved the hymen. We report an interesting case of the spontaneous formation of an imperforate hymen during pregnancy in the absence of previous surgical procedures. Electron microscopic findings indicate hymenal tissue reorganization.
文摘Objective: This study was undertaken to evaluate the role of secondary cytoreduction in patients with recurrent epithelial ovarian cancer. Study design: Secondarily, cytoreduced patients were retrospectively analyzed with respect to the clinicopathologic variables. Results: A total of 64 patients were evaluated in this report. Multivariable analysis revealed 3 factors to be significant: optimal cytoreduction during primary (P = .003, odds ratio [OR]: 0.30; 95%CI: 0.14-0.66), secondary cytoreduction (P = .04, OR: 0.47; 95%CI: 0.22-0.99), and the endometrioid histologic type (P = .005, OR: 0.09; 95%CI: 0.02-0.48). Intrinsic factors of the tumors (grade, stage, age), size, and number of recurrent tumors were nonsignificant. Conclusion: Secondary cytoreductive surgery should be offered in selected recurrent epithelial ovarian cancer patients. Further prospective randomized series are needed to determine specific recommendations.