The first lung transplantation in the rat was achieved by Asimacopoulos et al using sutured anastomoses in 1971.Subsequent development of a cuffed technique to construct the anastomoses by Mizuta and colleagues in 198...The first lung transplantation in the rat was achieved by Asimacopoulos et al using sutured anastomoses in 1971.Subsequent development of a cuffed technique to construct the anastomoses by Mizuta and colleagues in 1989 represented a breakthrough that resulted in simplification of the procedure and shorter warm is-chemic times.Since then,a number of further variations on the technique of rat lung transplantation have been described.In spite of this,the procedure remains technically demanding and involves a long learning curve.This minireview describes the following new technical safeguards to further evolve the technique for cuffed anastomoses in rat lung transplantation:the use of anatomical landmarks to avoid twisting of the everted donor pulmonary vein and bronchus in the cuff,the use of the cuff tie as a landmark to avoid twisting of the anastomotic cuffs relative to the recipient vessels,distal ties on the recipient vessels to achieve a bloodless field and triangulation of the venotomy to avoid pulmonary vein tearing.展开更多
文摘The first lung transplantation in the rat was achieved by Asimacopoulos et al using sutured anastomoses in 1971.Subsequent development of a cuffed technique to construct the anastomoses by Mizuta and colleagues in 1989 represented a breakthrough that resulted in simplification of the procedure and shorter warm is-chemic times.Since then,a number of further variations on the technique of rat lung transplantation have been described.In spite of this,the procedure remains technically demanding and involves a long learning curve.This minireview describes the following new technical safeguards to further evolve the technique for cuffed anastomoses in rat lung transplantation:the use of anatomical landmarks to avoid twisting of the everted donor pulmonary vein and bronchus in the cuff,the use of the cuff tie as a landmark to avoid twisting of the anastomotic cuffs relative to the recipient vessels,distal ties on the recipient vessels to achieve a bloodless field and triangulation of the venotomy to avoid pulmonary vein tearing.
