OBJECTIVE: To evaluate the effects of homoeopathic ultrahigh dilutions of Aconitum napellus in Baker's yeast-induced fever in rabbits. METHODS: Rabbits were divided into 4 groups and each group contained 6 rabbits....OBJECTIVE: To evaluate the effects of homoeopathic ultrahigh dilutions of Aconitum napellus in Baker's yeast-induced fever in rabbits. METHODS: Rabbits were divided into 4 groups and each group contained 6 rabbits. Baker's yeast suspension (20%) was injected subcutaneously. After fever induction, paracetamol and homoeopathic ultrahigh dilutions (A. nape//us 200c and 1 000c) were given orally. Rectal temperature was measured with digital thermometer hourly. RESULTS: Fever was induced in all the rabbits after 4 hours of Baker's yeast administration. A. nape//us 200c and 1000c significantly reduced the temperature (P 〈 0.05). In positive control, temperature decrease was more significant (P 〈 0.001 ). CONCLUSION: The above findings indicate the effectiveness of ultrahigh dilutions ofA. nape//us in Baker's yeast-induced fever in rabbits. However, the effects were slower and less significant than standard medicine Moreover, future research is required to know their mechanism of reducing temperature.展开更多
文摘OBJECTIVE: To evaluate the effects of homoeopathic ultrahigh dilutions of Aconitum napellus in Baker's yeast-induced fever in rabbits. METHODS: Rabbits were divided into 4 groups and each group contained 6 rabbits. Baker's yeast suspension (20%) was injected subcutaneously. After fever induction, paracetamol and homoeopathic ultrahigh dilutions (A. nape//us 200c and 1 000c) were given orally. Rectal temperature was measured with digital thermometer hourly. RESULTS: Fever was induced in all the rabbits after 4 hours of Baker's yeast administration. A. nape//us 200c and 1000c significantly reduced the temperature (P 〈 0.05). In positive control, temperature decrease was more significant (P 〈 0.001 ). CONCLUSION: The above findings indicate the effectiveness of ultrahigh dilutions ofA. nape//us in Baker's yeast-induced fever in rabbits. However, the effects were slower and less significant than standard medicine Moreover, future research is required to know their mechanism of reducing temperature.