Ureas and carbamates are common motifs in pharmaceuticals,agrochemicals,biologically active com-pounds and organocatalysis applications.Herein,we report a significant advancement in this area and present a general met...Ureas and carbamates are common motifs in pharmaceuticals,agrochemicals,biologically active com-pounds and organocatalysis applications.Herein,we report a significant advancement in this area and present a general method for copper-catalyzed chemospecific C–C bond cleavage of amides to syn-thesize urea derivatives and carbamates at room temperature.展开更多
基金Financial support from the National Nature Science Foundation of China(21861030)the Inner Mongolia Nature Science Foundation(2021MS02030)+2 种基金the Special Founded Project for Cultivating Major Project of Inner Mongolia Normal University(2020ZD02)the Innovative and Entrepreneurial Startup Supporting Program of Returned Overseas Scholars of Inner Mongolia Autonomous Region,the Collaborative Innovation Center for Water Environmental Security of Inner Mongolia Autonomous Region(XTCX003)the Science and Technology Program of Inner Mongolia Autonomous Region(2020PT0003)is acknowledged.
文摘Ureas and carbamates are common motifs in pharmaceuticals,agrochemicals,biologically active com-pounds and organocatalysis applications.Herein,we report a significant advancement in this area and present a general method for copper-catalyzed chemospecific C–C bond cleavage of amides to syn-thesize urea derivatives and carbamates at room temperature.
