上扬子北缘川北地区结晶基底晶质石墨矿数据集

上扬子北缘川北地区出露的基底地层发育双层结构,其中上层的褶皱基底早已发现尖山、坪河、庙坪等中—大型、超大型石墨矿;但是直到最近,才在下层的结晶基底后河岩群汪家坪岩组细粒石英岩中发现了石墨矿。该矿体长约200米,宽约6.7米,矿体平均厚度4.9米,矿石平均品位5.13%。矿物组合为:石英+石墨+云母+黄铁矿+赤铁矿。该成果在上扬子北缘地区的发现,扩大了该区域的找矿前景,为区内晶质石墨矿的找矿工作提供了新的方向,同时为四川巴中地区超大型晶质石墨矿基地建设提供了新的资源潜力保障。数据集包括Excel表格数据,2个*.xls类型文件,记录了样品固定碳测试结果和氧化物测试数据。

Sequential Observation of Alkali-halide Gas Phase Clusters in High Resolution TOF-MS and Prediction of Their Structures

Alkali halide clusters are interesting model systems that can provide information about how crystal properties evolve. To study these properties, a high-resolution atmospheric pressure inlet time-of-flight mass spectrometry （APi-TOF-MS） study of the sequential sodium halides series, C1-（NaC1）n and Br-（NaBr）m, has been reported, and the viability of the APi-TOF- MS equipped with an electrospray ionization source in determining cluster compositions has been demonstrated. The isotopic patterns were well resolved, as n=4 and 7 were determined to be the magic numbers for C1-（NaC1）n clusters, which were particularly abundant in the mass spectra. A global minimum search based on density functional theory enabled basin hopping yield the most stable structures for the mentioned series. The structures exhibit several distinct motifs which can be roughly categorized as linear chain, rock salt, and hexag- onal ring. This work provides an effective way to discover and elucidate the nonstoichiometry sodium halide clusters. These clusters possess very high vertical detachment energies and are generally called as superhalogens, which play important roles in chemistry because they are widely used in the synthesis of new classes of charge-transfer salts.

Systematic evaluation and Meta-analysis of the efficacy of Xiaochaihu Decoction in the treatment of chronic superficial gastritis

Objective:To compare the effectiveness of Xiaochaihu Decoction(XCHD)or the modified XCHD combined with western medicine in the treatment of superficial gastritis.Methods:We collected the studies about XCHD or the modified XCHD combined with western medicine for superficial gastritis in China Biology Medicine(CBM)Database(2010-2018),China National Knowledge Infrastructure(CNKI)Database(2010-2018),VIP Database(2010-2018),Wanfang Database(2010-2018)and the Back Issues Database of Hebei University.The randomized controlled trials(RCTs)were included in this study.The literatures were independently extracted by two researchers and the Cochrane Review Handbook(version 5.1.0)was applied to assess the quality of included trials.Statistical analysis was performed with RevMan(version 5.3).Results:A total of 8 RCTs,including 732 cases,were included finally.Meta-analysis results showed that compared with the western medicine treatment group,XCHD or the modified XCHD combined with western medicine could improve the total effective rate[OR=4.67,95%CI(2.90,7.55),P<0.00001],physiological function[MD=10,95%CI(8.78,11.23),P<0.00001],role physical[MD=13.85,95%CI(11.19,16.51),P<0.00001],physical pain[MD=11.64,95%CI(9.05,14.23),P<0.00001],general health[MD=11.20,95%CI(9.52,12.88),P<0.00001],vitality[MD=13.46,95%CI(12.30,14.62),P<0.00001],social function[MD=19.20,95%CI(17.32,21.09),P<0.00001],affection function[MD=30.3,95%CI(28.99,31.62),P<0.00001],mental health[MD=9.80,95%CI(8.44,11.16),P<0.00001].Conclusion:XCHD or the modified XCHD combined with western medicine in the treatment of superficial gastritis has good performance in clinical efficacy and the improvement of quality of life.However,with several methodology problems existing in the included RCTs,the effectiveness of XCHD or the modified XCHD is still need more high-quality randomized,double-blind,placebo-controlled trials to further confirmed.

A review of the treatment of ankylosing spondylitis from liver and kidney

Ankylosing spondytitis is a kind of arthropathy of rheumatic immune disease. The pathogenesis of ankylosing spondytitis is not very ctear in current medicat research. Because of the recurrence of the disease and the prolongation of the disease, the quality of tife of the patients has been seriously affected. Traditional Chinese medicine has tong known its etiotogy and pathogenesis, and it is very effective in ctinicat treatment. Based on the theory of traditional Chinese medicine and modern physicians' understanding of its etiotogy and pathogenesis, and starting from the function and characteristics of tiver and kidney, this paper explores the basis of treating ankylosing spondytitis from tiver and kidney, with a view to providing new ideas for the ctinicat treatment of ankylosing spondytitis.

A Review of RGB-D Camera Calibration Methods

RGB-D camera is a new type of sensor,which can obtain the depth and texture information in an unknown 3D scene simultaneously,and they have been applied in various fields widely.In fact,when implementing such kinds of applications using RGB-D camera,it is necessary to calibrate it first.To the best of our knowledge,at present,there is no existing a systemic summary related to RGB-D camera calibration methods.Therefore,a systemic review of RGB-D camera calibration is concluded as follows.Firstly,the mechanism of obtained measurement and the related principle of RGB-D camera calibration methods are presented.Subsequently,as some specific applications need to fuse depth and color information,the calibration methods of relative pose between depth camera and RGB camera are introduced in Section 2.Then the depth correction models within RGB-D cameras are summarized and compared respectively in Section 3.Thirdly,considering that the angle of the view field of RGB-D camera is smaller and limited to some specific applications,we discuss the calibration models of relative pose among multiple RGB-D cameras in Section 4.At last,the direction and trend of RGB-D camera calibration are prospected and concluded.

A COMPACTNESS THEOREM FOR STABLE FLAT SL(2, C) CONNECTIONS ON 3-FOLDS

Let Y be a closed 3-manifold such that all flat SU(2)-connections on Y are non-degenerate.In this article,we prove a Uhlenbeck-type compactness theorem on Y for stable flat SL(2,C)connections satisfying an L^(2)-bound for the real curvature.Combining the compactness theorem and a result from[7],we prove that the moduli space of the stable flat SL(2,C)connections is disconnected under certain technical assumptions.

Progress of blood-letting puncture on the treatment of psoriasis

Psoriasis is a chronic skin disease characterized by localized or wide spread squamous erythema or plaque. The pathogenesis is complicated. According to the TCM theory, psoriasis results from internal heat toxin and the deficiency of blood. And blood stasis exists throughout the disease, the treatment should focus on promoting blood circulation and removing blood stasis. Blood-letting puncture can balance Qi and blood through stimulating the meridians, forcing evil Qi to go out, so as to dispel pathogenic factors and dredge the meridians. This article briefly discusses the basic mechanisms and clinical researches of psoriasis with blood-letting puncture, in order to provide new ideas for the clinical treatment of psoriasis.

Syndrome differentiation of Zang-Fu for Tourette syndrome in children

As a kind of psychoneurotic disease, the incidence of Tourette syndrome (TS) is increasing graduaLy in recent years. Modern medicine for the pathogenesis of this disease has not been cteary in the treatment is mainty symptomatic treatment. Based on syndrome differentiation and treatment traditional medicine treats the unique system of etiotogy and pathogenesis of the disease, and achieves remarkable results in treatment. Chinese medicine treatment of children's diseases generaLy from the viscera diatecticaL In this paper, we summarize the ctinicat experience of the treatment of pediatric TS by syndrome differentiation of viscera in order to provide reference for the ctinicat treatment and research of pediatric TS.

Combination of Chinese and Western medicine in the treatment of aggressive angiomyxoma:a case report

Aggressive angiomyxoma(AAM)is a rare soft tissue tumor.Invasiveness and recurrence are important clinical features of AAM.A patient with recurrent AAM was admitted to the hospital.At present,the treatment for AAM is still based on surgery because it does not have lymph nodes and distant metastasis.Moreover,chemotherapy is of little significance.Traditional Chinese medicine believes the formation of tumor is related to blood stasis,so after surgery,a Chinese medicine called Xue-Shuan-Tong was used to improve blood circulation and disperses stasis.The drainage tube was removed on the 5th day after the operation and achieved a good wound healing.This article analyzes and demonstrates the pathogenesis of female vulvar invasive angiomyxoma from the perspective of modern medicine and traditional medicine,in order to provide a better understanding of the disease.

History and Modern Application of Chinese Physical and Breathing Exercises

Traditional Chinese medicine is the key to open the treasure house of Chinese civilization.Traditional Chinese medicine treatment includes drugs,acupuncture,massage,cupping and other means.Chinese physical and breathing exercises is one of the most effective methods of exercise among various treatments.Chinese physical and breathing exercises can soften muscles and strengthen bones.It has the functions of activating blood circulation and regulating the internal organs and internal organs.It can enhance physical fitness,prevent disease and cure diseases,and achieve the purpose of prolonging life.In order to provide guidance for the prevention and treatment of clinical diseases,this paper summarized the literature records,theoretical basis,clinical application and related literature reports of Chinese physical and breathing exercises.

Diagnosis and treatment of psoriatic arthritis with concealed rash: a case report

Psoriatic arthritis is a kind of arthritis associated with psoriasis. The clinical manifestations of psoriatic arthritis with arthritis as the first symptom are often similar to ankylosing spondylitis and rheumatoid arthritis. Thus differential diagnosis should be made in clinical practice so as to improve the therapeutic effect. Psoriatic arthritis skin lesions are usually papules or plaques, with scales on the surface and punctate hemorrhage on the basement. About 10% of patients with psoriatic arthritis have skin rash after the onset of arthritis. In order to provide a reference for clinicians, our study the analyzed the clinical diagnosis of psoriatic arthritis in combination with a case of psoriatic arthritis with concealed skin rash and related literatures.

Rheumatoid arthritis and ankylosing spondylitis occurring together: a case report

Ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are two different rheumatoid immune diseases. It is not common that the two diseases occur simultaneously in the same patient in clinical practice. Here, we reported a case of meeting the diagnostic criteria for both AS and RA, who was treated with integrated traditional Chinese and Western medicine and received apparent improvement.

SnapshotPrune: A Novel Bitcoin-Based Protocol Toward Efficient Pruning and Fast Node Bootstrapping

Node synchronization is essential for the stability of the Bitcoin network. Critics have raised doubts about the ability of a new node to quickly and efficiently synchronize with the Bitcoin network and alleviate the storage pressure from existing full nodes to stockpile new data. Basic pruning and other techniques have been explored to address these concerns but have been insufficient to reduce node synchronization delay and effectively suppress the growth of synchronized data. In this study, we propose SnapshotPrune, a novel pruning and synchronization protocol that achieves fast node bootstrapping in the Bitcoin blockchain. Real Bitcoin historical data are leveraged to measure the synchronization time and monitor the network traffic during node bootstrapping. The protocol requires data downloads that are 99.70% less than Bitcoin Core, 81% less than CoinPrune, and 60% less than SnapshotSave, thereby saving 97.23% of download time. Findings show that the proposed design enhances the storage efficiency and reduces the node synchronization delay compared with existing techniques. We hypothesize that the efficiency of this protocol increases with the block height.

Etiological roles of core promoter variation in triple-negative breast cancer

Abnormal geneexpression playskeyrole in cancerdevelopment.Acorepromoter is located around the transcriptional start site.Through interaction between core promoter sequences and transcriptional factors,core promoter controls transcriptional initiation.We hypothesized that in cancer,core promoter sequences could be mutated to interfere the interaction with transcriptional factors,resulting in altered transcriptional initiation and abnormal gene expression and cancer development.We used triple-negative breast cancer(TNBC)as a model to test our hypothesis.We collected genome-wide core promoter variants from 279 TNBC genomes.After extensive filtering of normal genomic polymorphism,we identified 19,427 recurrent somatic variants in 1,238 core promoters of 1,274 genes and 1,694 recurrent germline variants in 272 core promoters of 294 genes.Many of the affected genes were oncogenes and tumor suppressors.Analysis of RNA-seq data from the same patient cohort identified increased or decreased gene expression in 439 somatic and 85 germline variantsaffected genes,and the results were validated by luciferase reporter assay.By comparing with the core promoter variation data from 610 unclassified breast cancer,we observed that core promoter variants in TNBC were highly TNBC-specific.We further identified the drugs targeting the genes with core promoter variation.Our study demonstrates that core promoter is highly mutable in cancer,and can play etiological roles in TNBC and other types of cancer through influencing transcriptional initiation.

Efficacy,safety and immunogenicity of hexavalent rotavirus vaccine in Chinese infants

A randomized,double-blind,placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy and safety of a hexavalent live human-bovine reassortant rotavirus vaccine(HRV)against rotavirus gastroenteritis(RVGE).A total of 6400 participants aged 6-12 weeks were enrolled and randomly assigned to either HRV(n?3200)or placebo(n?3200)group.All the subjects received three oral doses of vaccine four weeks apart.The vaccine efficacy(VE)against RVGE caused by rotavirus serotypes contained in HRV was evaluated from 14 days after three doses of administration up until the end of the second rotavirus season.VE against severe RVGE,VE against RVGE hospitalization caused by serotypes contained in HRV,and VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were also investigated.All adverse events(AEs)were collected for 30 days after each dose.Serious AEs(SAEs)and intussusception cases were collected during the entire study.Our data showed that VE against RVGE caused by serotypes contained in HRV was 69.21%(95%CI:53.31-79.69).VE against severe RVGE and RVGE hospitalization caused by serotypes contained in HRV were 91.36%(95%CI:78.45-96.53)and 89.21%(95%CI:64.51-96.72)respectively.VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were 62.88%(95%CI:49.11-72.92),85.51%(95%CI:72.74-92.30)and 83.68%(95%CI:61.34-93.11).Incidences of AEs from the first dose to one month post the third dose in HRV and placebo groups were comparable.There was no significant difference in incidences of SAEs in HRV and placebo groups.This study shows that this hexavalent reassortant rotavirus vaccine is an effective,well-tolerated,and safe vaccine for Chinese infants.

Construction and analysis of an integrated biological network of Escherichia coli

Escherichia coli is a model organism with a clear genetic background that is widely used in metabolic engineering and synthetic biology research.To gain a complete picture of the complexly metabolic and regulatory interactions in E.coli,researchers often need to retrieve information from various databases which cover diferent types of interactions.A central one-stop service integrating various molecular interactions in E.coli would be helpful for the community.We constructed a database called E.coli integrated network(EcoIN)by integrating known molecular interaction information from databases and literature.EcoIN contains nearly 160,000 pairs of interactions and users can easily search the diferent types of interacting partners for a metabolite,gene or protein,and thus gain access to a more comprehensive interaction map of E.coli.To illustrate the application of EcoIN,we used the full path algorithm to identify metabolic feedback/feedforward regulatory loops having at least two diferent types of regulatory interactions.Applying this algorithm to analyze the regulatory loops for the amino acid biosynthetic pathways,we found some multi-step regulation loops which may afect the metabolic fux and are potential new engineering targets.The EcoIN database is freely accessible at http://ecoin.ibiodesign.net/and analysis codes are available at GitHub:https://github.com/maozhitao/EcoIN.