In this study,we focus on the alteration of the programmed cell death 1(PD-1)/PD-L1 pathway in celiac disease.We discuss the diverse roles of the PD-1 pathway in regulating immune responses and how this knowledge can ...In this study,we focus on the alteration of the programmed cell death 1(PD-1)/PD-L1 pathway in celiac disease.We discuss the diverse roles of the PD-1 pathway in regulating immune responses and how this knowledge can improve celiac disease(CD)autoimmunity.The PD-1 and PD-L1 levels in the serum and in intestinal biopsies of CD patients may be relevant to the determination of a possible correlation between markers of the autoimmune response,inflammation,and disease activity.展开更多
基金This work was supported by Research group BIO220,Junta de Andalucía.
文摘In this study,we focus on the alteration of the programmed cell death 1(PD-1)/PD-L1 pathway in celiac disease.We discuss the diverse roles of the PD-1 pathway in regulating immune responses and how this knowledge can improve celiac disease(CD)autoimmunity.The PD-1 and PD-L1 levels in the serum and in intestinal biopsies of CD patients may be relevant to the determination of a possible correlation between markers of the autoimmune response,inflammation,and disease activity.
