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视乳头破裂出血的发病机制的一种新的假说
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作者 Grieshaber M.C. terhorst t. +1 位作者 Flammer J. 安胜 《世界核心医学期刊文摘(眼科学分册)》 2006年第8期11-11,共1页
Purpose: To describe a hypothesized relationship between optic disc haemorrhages (ODHs) and primary vascular dysregulation (PVD). Methods: Observational case report of a patient with classical PVD and five bilateral r... Purpose: To describe a hypothesized relationship between optic disc haemorrhages (ODHs) and primary vascular dysregulation (PVD). Methods: Observational case report of a patient with classical PVD and five bilateral recurrent ODHs. Results: The ODHs were superotemporal in the right eye and inferotemporal in the left; the eyes were otherwise normal. Intraocular pressure (IOP) never exceeded 17 mmHg. Visual fields were normal. Increased blood flow resistivity, a reduced blood flow of the extraocular vessels, a low systemic blood pressure, a cold-induced flow stop of the nailfold capillaries, and elevated endothelin-1 plasma levels were found, all confirming the diagnosis of vascular dysregulation. Conclusions: Optic disc haemorrhages may be due to a disturbed blood-retina barrier rather than to a mechanical rupture of the vessel. This barrier dysfunction may occur in the context of PVD. 展开更多
关键词 乳头破裂 发病机制 内皮缩血管肽 血流阻力 功能失调 乳头出血 观察性
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