As the cross-coupling needs of chemists continue to grow for accessing increasingly complex targets,radical-based transformations have become mainstay methodologies for the discovery of new reactivity under mild and w...As the cross-coupling needs of chemists continue to grow for accessing increasingly complex targets,radical-based transformations have become mainstay methodologies for the discovery of new reactivity under mild and wastelimiting conditions.En route to such methodological advancements,the observation of the 1,2-boron shift a novel radical rearrangement in its application has generated a new cross-coupling methodology to access products that were previously inaccessible or otherwise cumbersome to make.The origins of this radical rearrangement along with the synthetic applications to organic chemistry are highlighted.展开更多
Alternating current electrolysis(ACE)is an emerging powerful synthetic tool,which principally resembles photoredox catalysis strategies.Its periodically alternating polarity feature allows oxidation and reduction proc...Alternating current electrolysis(ACE)is an emerging powerful synthetic tool,which principally resembles photoredox catalysis strategies.Its periodically alternating polarity feature allows oxidation and reduction processes to take place on the same electrode surface in a well-controlled manner via the fine-tuning of current frequency along with other reaction parameters.Therefore,many challenging transformations in typical direct electrolysis,including constant current electrolysis or constant potential electrolysis,could be achieved via ACE.The recent advances in the organic synthesis using this emerging technology and its advantages over direct electrolysis are highlighted.展开更多
文摘As the cross-coupling needs of chemists continue to grow for accessing increasingly complex targets,radical-based transformations have become mainstay methodologies for the discovery of new reactivity under mild and wastelimiting conditions.En route to such methodological advancements,the observation of the 1,2-boron shift a novel radical rearrangement in its application has generated a new cross-coupling methodology to access products that were previously inaccessible or otherwise cumbersome to make.The origins of this radical rearrangement along with the synthetic applications to organic chemistry are highlighted.
基金This work was supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.NRF-2021R1C1C1004605)(H.Kim)the National Natural Science Foundation of China(Nos.22171046,21901041)(K.Y).
文摘Alternating current electrolysis(ACE)is an emerging powerful synthetic tool,which principally resembles photoredox catalysis strategies.Its periodically alternating polarity feature allows oxidation and reduction processes to take place on the same electrode surface in a well-controlled manner via the fine-tuning of current frequency along with other reaction parameters.Therefore,many challenging transformations in typical direct electrolysis,including constant current electrolysis or constant potential electrolysis,could be achieved via ACE.The recent advances in the organic synthesis using this emerging technology and its advantages over direct electrolysis are highlighted.
