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心肌梗塞后大鼠心肌组织中神经肽Y Y_1受体mRNA水平的改变
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作者 陆利民 孙祥莺 +5 位作者 汪军 田德志 郑峪 朱依纯 thomas hedner 姚泰 《高血压杂志》 CSCD 2001年第2期134-137,共4页
目的 观察心肌梗塞后心肌组织中神经肽Y(NPY)Y1受体水平的改变。方法 实验在雄性Sprague Daw ley大鼠中进行 ,用结扎大鼠冠状动脉左前降支的方法 ,造成心肌梗塞动物模型 ,用RT PCR方法观察心肌组织中是否存在有NPYY1受体mRNA ,用定量... 目的 观察心肌梗塞后心肌组织中神经肽Y(NPY)Y1受体水平的改变。方法 实验在雄性Sprague Daw ley大鼠中进行 ,用结扎大鼠冠状动脉左前降支的方法 ,造成心肌梗塞动物模型 ,用RT PCR方法观察心肌组织中是否存在有NPYY1受体mRNA ,用定量PCR方法观察心肌梗塞后大鼠心肌组织中NPYY1受体mRNA水平的改变。结果 用RT PCR方法观察到 ,大鼠心肌组织中有NPYY1受体mRNA分布。在大鼠结扎冠状动脉一天及三天后 ,梗塞区及非梗塞区心肌组织中NPYY1受体mRNA水平较假手术组大鼠均有显著升高。此外 ,假手术组大鼠心肌组织中NPYY1受体mRNA水平较正常大鼠也有显著升高。结论 心肌梗塞可导致梗塞区及非梗塞区心肌组织中NPYY1受体水平升高 ,手术创伤应激也可影响心肌组织中NPYY1受体水平。 展开更多
关键词 神经肽Y 心肌梗塞 RT-PCR
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The Effect of A100 Gel, on Hair Growth and Hair Quality: An Explanatory Study
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作者 Jan Faergemann thomas hedner 《Journal of Cosmetics, Dermatological Sciences and Applications》 2016年第1期19-23,共5页
Male pattern baldness or androgenic alopecia is a great problem for many individuals’ especially young people. A100 is composed of two active ingredients, a pollen extract and pentane-1,5-diol. The pollen extract pro... Male pattern baldness or androgenic alopecia is a great problem for many individuals’ especially young people. A100 is composed of two active ingredients, a pollen extract and pentane-1,5-diol. The pollen extract provides a source of natural nutrients and pentane-1,5-diol acts as a solvent to unplug the hair follicle as well as acts as an enhancer for uptake of nutrients. Other components are claimed to increase blood flow to the hair papilla. A100 has been effective in earlier studies. The aim of this open explanatory study was to investigate the effect of 4 months twice daily application with this commercial pollen gel, A100, in subjects with male androgenic alopecia. Twenty male subjects, between 18 and 40 years with androgenic alopecia were included. A100 gel was applied to the area of the scalp with poor hair growth twice daily for 4 months. The subjects were seen at the start of treatment and then every month. Sixteen subjects fulfilled the whole 4 months of treatment and 2 fulfilled 3 months of treatment. A statistically significant increase in number of hairs was seen after 4 months of treatment with A100 (p < 0.001). This effect was seen for all types of hair. Fifty-six percent of the 16 subjects who fulfilled the 4 months treatment had an increase in hair growth of more than 50%, and 31% had an increase over 100%. No side effects were seen and the subjects found A100 gel a cosmetically attractive treatment. A100 was in this explanatory study an effective and safe treatment for androgenic alopecia or male pattern baldness. 展开更多
关键词 Pollen Extract Pentane-1 5-Diol Explanatory Androgenic Alopecia
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