Synthetic biology is constantly making progress for producing compounds on demand.Recently,Yocum and collaborators have developed an outstanding approach based on the anchoring of biosynthetic enzymes to the peroxisom...Synthetic biology is constantly making progress for producing compounds on demand.Recently,Yocum and collaborators have developed an outstanding approach based on the anchoring of biosynthetic enzymes to the peroxisomal membrane.This allowed access to an untapped resource of acetyl-CoA and stimulated the synthesis of a valuable polyketide.展开更多
基金funding from the EU Horizon 2020 research and innovation program(MIAMi project-Grant agreement N°814645)ARD-CVL Biopharmaceutical program of the Region Centre Val de Loire(ETOPOCentre project),Le Studium Institute(Consortium Fellowship)and ANR(project MIACYC-ANR-20-CE43-0010).
文摘Synthetic biology is constantly making progress for producing compounds on demand.Recently,Yocum and collaborators have developed an outstanding approach based on the anchoring of biosynthetic enzymes to the peroxisomal membrane.This allowed access to an untapped resource of acetyl-CoA and stimulated the synthesis of a valuable polyketide.