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对比增强谐波超声显像肝转移癌及血流特征
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作者 王迎 李建海 thomas vogl 《新疆医科大学学报》 CAS 2005年第10期986-988,共3页
目的:探讨应用对比增强谐波超声方法显像肝转移癌及其血流特征。方法:16例20个肝内局灶转移癌。将24 ml造影剂SonoVue经前臂静脉注入后进行对比增强谐波超声方法(ECI)扫描,并连续观察记录病灶局部影像,共4 min,历经动脉期、门脉期、实... 目的:探讨应用对比增强谐波超声方法显像肝转移癌及其血流特征。方法:16例20个肝内局灶转移癌。将24 ml造影剂SonoVue经前臂静脉注入后进行对比增强谐波超声方法(ECI)扫描,并连续观察记录病灶局部影像,共4 min,历经动脉期、门脉期、实质期。结果:10/20个病灶于血管期呈现绕病变周边部的近完整或不完整的细环状增强;7/20个病灶于整个观察期未显示血流征象;2/20个病灶内部少许不典型点状、细条状血流分布显示于血管期;1/20个病灶于常规超声检查中未显像,实质期局部无增强,在周围正常组织增强映衬下呈类“黑洞征”。结论:血管期的肿瘤血供形式具有重要的鉴别意义即肝转移癌在血管期呈环状增强或无增强,实质期局部无增强。超声造影剂的使用可以提高肝转移癌的检出率。 展开更多
关键词 超声诊断 造影剂 谐波研究 肝脏肿瘤 转移癌 血流特征
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Computed Tomography Guided Percutaneous Liver Biopsy Using a Robotic Assistance Device—A Corpse Study
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作者 Boris Schulz Katrin Eichler +4 位作者 Firas Al-Butmeh Claudia Frellesen Christoph Czerny thomas vogl Stephan Zangos 《Open Journal of Radiology》 2015年第2期84-91,共8页
Purpose: To investigate a robot assistance device for CT-guided percutan liver biopsy. Materials and Methods: The liver of a corpse was equipped with target dummies. Four radiologists used a 16 G needle to perform bio... Purpose: To investigate a robot assistance device for CT-guided percutan liver biopsy. Materials and Methods: The liver of a corpse was equipped with target dummies. Four radiologists used a 16 G needle to perform biopsy of the target region in standard free hand technique and then used a robot system which allowed planning and aligning the trajectory path. Accuracy in terms of needle tip deviation, and time efficiency and radiation exposure in terms of effective dose for the radiologists were measured. Results: For in plane procedures, there was no significant benefit in accuracy when using the robot versus standard technique (4 mm vs. 5.6 mm, p = 0.11);timely effort was worse (443 sec vs. 405 sec, p = 0.64). For angulated punctures, a needle tip of 3.7 mm was measured by using the robotic device (vs. 10.8 mm, p < 0.01);mean biopsy duration was 490 sec (vs. 900 sec, p < 0.01). Mean radiation exposures in freehand technique were 2.4 μSv (in plane procedures) and 10.8 μSv (oblique procedures);the robotic assisted procedures were performed without additional image guidance. Conclusion: The proposed robotic assistance device may be superior for angulated interventions regarding accuracy and timely effort. Furthermore, the zero radiation exposure is a significant benefit for the interventional radiologist. 展开更多
关键词 INTERVENTIONAL RADIOLOGY ROBOTIC ASSISTANCE Needle BIOPSY Radiation Dose
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白芨在介入治疗大鼠肝细胞癌实验中的比较研究 被引量:7
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作者 钱骏 郑传胜 +5 位作者 吴汉平 黎维勇 Vossoughi Daryusch Elsie Oppermann thomas vogl 冯敢生 《中华肝脏病杂志》 CAS CSCD 北大核心 2005年第2期143-144,共2页
肝癌是我国最常见的恶性肿瘤之一,经肝动脉化疗栓塞术(TACE)被公认为治疗不可切除性中、晚期肝癌的一种重要手段[1].本研究旨在通过建立肝细胞癌大鼠模型,在此模型上考察以白芨微粒作肝动脉栓塞剂并与抗肿瘤血管生成药物、免疫反应调节... 肝癌是我国最常见的恶性肿瘤之一,经肝动脉化疗栓塞术(TACE)被公认为治疗不可切除性中、晚期肝癌的一种重要手段[1].本研究旨在通过建立肝细胞癌大鼠模型,在此模型上考察以白芨微粒作肝动脉栓塞剂并与抗肿瘤血管生成药物、免疫反应调节剂相比介入治疗大鼠肝细胞癌的疗效. 展开更多
关键词 白芨 大鼠肝细胞 介入治疗 大鼠模型 常见 成药 肝动脉栓塞 手段 实验 中国
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CREMa overexpression decreases IL-2 production,induces a TH17 phenotype and accelerates autoimmunity 被引量:2
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作者 Ralph Lippe Kim Ohl +17 位作者 Georg Varga thomas Rauen Jose C.Crispin Yuang-Taung Juang Stefanie Kuerten Frank Tacke Marc Wolf Kirsten Roebrock thomas vogl Eva Verjans Nora Honke Jan Ehrchen Dirk Foell Boris Skryabin Norbert Wagner George C.Tsokos Johannes Roth Klaus Tenbrock 《Journal of Molecular Cell Biology》 SCIE CAS CSCD 2012年第2期121-123,共3页
Dear Editor,External cytokines produced by cells of the innate immune system induce the dif-ferentiation of CD4+T cells into helper T cell subsets with distinct functions and cytokine profiles.Apart from TH1 and TH2 c... Dear Editor,External cytokines produced by cells of the innate immune system induce the dif-ferentiation of CD4+T cells into helper T cell subsets with distinct functions and cytokine profiles.Apart from TH1 and TH2 cells a third subset of helper T cells has been described,which is characterized by increased expression of IL-17A,IL-17F,IL-21 and IL-22(TH17 cells). 展开更多
关键词 TH17 INDUCE cytokines
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