Due to the energy-dense but nutrient-deficient diets,sedentary lifestyle and lack of exercise as well as an aging population,the prevalence and incidence of overweight/obesity/sarcopenic obesity,type 2 diabetes mellit...Due to the energy-dense but nutrient-deficient diets,sedentary lifestyle and lack of exercise as well as an aging population,the prevalence and incidence of overweight/obesity/sarcopenic obesity,type 2 diabetes mellitus(T2DM),metabolic syndrome and their related non-alcoholic fatty liver disease(NAFLD)have been increasing globally in the last two decades.In Europe and the United States,NAFLD has become the second leading cause of end-stage liver disease and liver transplantation(1).Worse still,the onset age of NAFLD is becoming younger tendency.Although the new nomenclature of metabolic dysfunction-associated fatty liver disease(MAFLD)has been proposed for 3 years,MAFLD is not equivalent to NAFLD,and few epidemiologic investigations on MAFLD to date.Therefore,this invited editorial is focus on the global epidemiology of NAFLD and the major impact on China.展开更多
基金supported by the National Natural Science Foundation of China(Nos.82170593,81900507).
文摘Due to the energy-dense but nutrient-deficient diets,sedentary lifestyle and lack of exercise as well as an aging population,the prevalence and incidence of overweight/obesity/sarcopenic obesity,type 2 diabetes mellitus(T2DM),metabolic syndrome and their related non-alcoholic fatty liver disease(NAFLD)have been increasing globally in the last two decades.In Europe and the United States,NAFLD has become the second leading cause of end-stage liver disease and liver transplantation(1).Worse still,the onset age of NAFLD is becoming younger tendency.Although the new nomenclature of metabolic dysfunction-associated fatty liver disease(MAFLD)has been proposed for 3 years,MAFLD is not equivalent to NAFLD,and few epidemiologic investigations on MAFLD to date.Therefore,this invited editorial is focus on the global epidemiology of NAFLD and the major impact on China.