Phenylacetic acid(PAA)is a primary raw material for illegal Methamphetamine(MATM)synthesis under the strong precursor chemicals supervisions of safrole and isosafrole.Therefore,trace detection of PAA at ultra-low conc...Phenylacetic acid(PAA)is a primary raw material for illegal Methamphetamine(MATM)synthesis under the strong precursor chemicals supervisions of safrole and isosafrole.Therefore,trace detection of PAA at ultra-low concentration is a strategic technique and an urgent issue in the field of drug control.In this paper,trace determination of PAA at sub-nmol-L-1 concentration level is achieved by hydrogen bond adsorption and electrochemical catalysis through the prepared aminated SiO_(2)nanoparticles(SiO_(2)-NH_(2) NPs)and MoS_(2) nanosheets(NSs)modified glassy carbon electrode(GCE).The prepared MoS_(2) NS s/SiO_(2)-NH_(2) NPs modified electrode represents a detecting limit of 0.0989 nmol·L^(-1)and an obvious increasing linear range before the concentration increasement up to 60 nmol·L^(-1)in square wave voltammetry(SWV)responses of PAA.The SWV response of the modified electrode to PAA in the concentration range within 100 nmol·L^(-1)is higher than phenol,acetic acid(HOAc)and benzoic Acid(BEN).This electrochemical method for trace detection of PAA in aqueous solution with desired performance provides a feasible scheme for the detection of other drugs and aromatic precursor chemicals.展开更多
基金financially supported by the National Natural Science Foundation of China (Nos.62033002,62071112 and 61973058)the Program of the Ministry of Education of China for Introducing Talents of Discipline to Universities (No.B16009)+1 种基金the Fundamental Research Funds for the Central Universities in China (No.N2201008)Hebei Natural Science Foundation (No.F2020501040)。
文摘Phenylacetic acid(PAA)is a primary raw material for illegal Methamphetamine(MATM)synthesis under the strong precursor chemicals supervisions of safrole and isosafrole.Therefore,trace detection of PAA at ultra-low concentration is a strategic technique and an urgent issue in the field of drug control.In this paper,trace determination of PAA at sub-nmol-L-1 concentration level is achieved by hydrogen bond adsorption and electrochemical catalysis through the prepared aminated SiO_(2)nanoparticles(SiO_(2)-NH_(2) NPs)and MoS_(2) nanosheets(NSs)modified glassy carbon electrode(GCE).The prepared MoS_(2) NS s/SiO_(2)-NH_(2) NPs modified electrode represents a detecting limit of 0.0989 nmol·L^(-1)and an obvious increasing linear range before the concentration increasement up to 60 nmol·L^(-1)in square wave voltammetry(SWV)responses of PAA.The SWV response of the modified electrode to PAA in the concentration range within 100 nmol·L^(-1)is higher than phenol,acetic acid(HOAc)and benzoic Acid(BEN).This electrochemical method for trace detection of PAA in aqueous solution with desired performance provides a feasible scheme for the detection of other drugs and aromatic precursor chemicals.
