Micro/nanostructured components play an important role in micro-optics and optical engineering,tribology and surface engineering,and biological and biomedical engineering,among other fields.Precision glass molding tec...Micro/nanostructured components play an important role in micro-optics and optical engineering,tribology and surface engineering,and biological and biomedical engineering,among other fields.Precision glass molding technology is the most efficient method of manufacturing micro/nanostructured glass components,the premise of which is meld manufacturing with complementary micro/nanostructures.Numerous mold manufacturing methods have been developed to fabricate extremely small and high-quality micro/nanostructures to satisfy the demands of functional micro/nanostructured glass components for various applications.Moreover,the service performance of the mold should also be carefully considered.This paper reviews a variety of technologies for manufacturing micro/nanostructured molds.The authors begin with an introduction of the extreme requirements of mold materials.The following section provides a detailed survey of the existing micro/nanostructured mold manufacturing techniques and their corresponding mold materials,including nonmechanical and mechanical methods.This paper concludes with a detailed discussion of the authors recent research on nickel-phosphorus(Ni-P)mold manufacturing and its service performance.展开更多
Cellular metabolism arouses the changes of substance in extracellular physiological microenvironment,and the metabolic level reflects the physiological state of cells.This paper developed a novel microphysiometer auto...Cellular metabolism arouses the changes of substance in extracellular physiological microenvironment,and the metabolic level reflects the physiological state of cells.This paper developed a novel microphysiometer automatic analysis instrument based on multiparameter cell-based biosensors for quick drug analysis.This study included the multiparameter cell-based biosensors,cell culture chamber,drug auto-injection detection and analysis.The analysis instrument was capable of real-time detection for the acidic product and other chemical parameters generated by the cellular metabolism in the micro-volume.Finally,the paper employs human breast cancer cell line MCF-7 and drug experiments to verify the performance of microphysiometer,and study effects of different drugs on cell metabolism.Further,the research explores drug analysis method of the multiparameter microphysiometer.The results showed that the cell-based microphysiometer system provides a utility platform for rapid,long-term and automatic cell physiological environment detection and drug analysis.展开更多
We demonstrate a passively harmonic mode-locked(PHML) fiber laser operating at the L-band using carbon nanotubes polyvinyl alcohol(CNTs-PVA) film. Under suitable pump power and an appropriate setting of the polari...We demonstrate a passively harmonic mode-locked(PHML) fiber laser operating at the L-band using carbon nanotubes polyvinyl alcohol(CNTs-PVA) film. Under suitable pump power and an appropriate setting of the polarization controller(PC), the 54^(th) harmonic pulses at the L-band are generated with the side mode suppression ratio(SMSR) better than 44 dB and a repetition frequency of 503.37 MHz. Further increasing the pump power leads to a higher frequency of 550 MHz with compromised stability of 38.5 dB SMSR. To the best of our knowledge, this is the first demonstration on the generation of L-band PHML pulses from an Er-doped fiber laser based on CNTs.展开更多
The estimation of downward surface shortwave radiation(DSSR)is important for the Earth’s energy budget and climate change studies.This review was organised from the perspectives of satellite sensors,algorithms and fu...The estimation of downward surface shortwave radiation(DSSR)is important for the Earth’s energy budget and climate change studies.This review was organised from the perspectives of satellite sensors,algorithms and future trends,retrospects and summaries of the satellite-based retrieval methods of DSSR that have been developed over the past 10 years.The shortwave radiation reaching the Earth’s surface is affected by both atmospheric and land surface parameters.In recent years,studies have given detailed considerations to the factors which affect DSSR.It is important to improve the retrieval accuracy of cloud microphysical parameters and aerosols and to reduce the uncertainties caused by complex topographies and high-albedo surfaces(such as snow-covered areas)on DSSR estimation.This review classified DSSR retrieval methods into four categories:empirical,parameterisation,look-up table and machine-learning methods,and evaluated their advantages,disadvantages and accuracy.Further efforts are needed to improve the calculation accuracy of atmospheric parameters such as cloud,haze,water vapor and other land surface parameters such as albedo of complex terrain and bright surface,organically combine machine learning and other methods,use the new-generation geostationary satellite and polar orbit satellite data to produce highresolution DSSR products,and promote the application of radiation products in hydrological and climate models.展开更多
The use of submicron structures for structural coloration of surfaces has broad applications for color filters,projection displays,virtual reality,and anti-counterfeiting.Currently,structural color images lack high re...The use of submicron structures for structural coloration of surfaces has broad applications for color filters,projection displays,virtual reality,and anti-counterfeiting.Currently,structural color images lack high resolution due to low manufacturing accuracy.In this study,the axial-feed fly cutting(AFC)method is proposed to fabricate submicron grooves for the diffraction of visible light to create structural color images.We establish the relationship between the color information in the pixels of the original image and the parameters of the array units corresponding to the pixels.An algorithm to determine groove spacing and the tool path is established,and array units with the desired groove spacing are machined to reproduce the structural color images.The submicron grooves fabricated by AFC have high quality and good consistency.Due to the excellent diffraction performance of the machined grooves,images with high saturation and resolution can be reproduced.It is verified that images with various colors can be efficiently fabricated using the proposed method and algorithm.展开更多
Two-dimensional(2D)magnetic materials are essential for the development of the next-generation spintronic technologies.Recently,layered van der Waals(vdW)compound MnBi2Te4(MBT)has attracted great interest,and its 2D s...Two-dimensional(2D)magnetic materials are essential for the development of the next-generation spintronic technologies.Recently,layered van der Waals(vdW)compound MnBi2Te4(MBT)has attracted great interest,and its 2D structure has been reported to host coexisting magnetism and topology.Here,we design several conceptual nanodevices based on MBT monolayer(MBT-ML)and reveal their spin-dependent transport properties by means of the first-principles calculations.The pn-junction diodes and sub-3-nm pin-junction field-effect transistors(FETs)show a strong rectifying effect and a spin filtering effect,with an ideality factor n close to 1 even at a reasonably high temperature.In addition,the pip-and nin-junction FETs give an interesting negative differential resistive(NDR)effect.The gate voltages can tune currents through these FETs in a large range.Furthermore,the MBT-ML has a strong response to light.Our results uncover the multifunctional nature of MBT-ML,pave the road for its applications in diverse next-generation semiconductor spin electric devices.展开更多
We propose and demonstrate a passively harmonic mode-locked erbium-doped fiber laser(EDFL)using carbon nanotubes polyvinyl alcohol(CNTs-PVA)film.The laser allows generation of the pulses with a repetition rate of 580 ...We propose and demonstrate a passively harmonic mode-locked erbium-doped fiber laser(EDFL)using carbon nanotubes polyvinyl alcohol(CNTs-PVA)film.The laser allows generation of the pulses with a repetition rate of 580 MHz,which corresponds to the 22nd harmonics of a 26.3 MHz fundamental repetition rate under 323 mW pump power.A particularly noteworthy feature of the pulses is the super-mode suppression ratio(SMSR),which is over 40 dB,indicating a stable operation.展开更多
Electrophysiological recording is a widely used method to investigate cardiovascular pathology,pharmacology and developmental biology.Microelectrode arrays record the electrical potential of cells in a minimally invas...Electrophysiological recording is a widely used method to investigate cardiovascular pathology,pharmacology and developmental biology.Microelectrode arrays record the electrical potential of cells in a minimally invasive and highthroughput way.However,commonly used microelectrode arays primarily employ planar microelectrodes and cannot work in applications that require a recording of the intracellular action potential of a single cell.In this study,we proposed a novel measuring method that is able to record the intracellular action potential of a single cardiomyocyte by using a nanowell patterned microelectrode array(NWMEA).The NWMEA consists of five nanoscale wells at the center of each circular planar microelectrode.Biphasic pulse electroporation was applied to the NWMEA to penetrate the cardiomyocyte membrane,and the intracellular action potential was continuously recorded.The intracellular potential recording of cardiomyocytes by the NWMEA measured a potential signal with a higher quality(213.76±25.85%),reduced noise root-mean-square(~33%),and higher signal-to-noise ratio(254.36±12.61%)when compared to those of the extracellular recording.Compared to previously reported nanopillar microelectrodes,the NWMEA could ensure single cell electroporation and acquire high-quality action potential of cardiomyocytes with reduced fabrication processes.This NWMEA-based biosensing system is a promising tool to record the intracellular action potential of a single cell to broaden the usage of microelectrode arrays in electrophysiological investigation.展开更多
By using a combined method of density functional theory and non-equilibrium Green's function formalism,we investigate the electronic transport properties of carbon-doped armchair phosphorene nanoribbons(APNRs).The ...By using a combined method of density functional theory and non-equilibrium Green's function formalism,we investigate the electronic transport properties of carbon-doped armchair phosphorene nanoribbons(APNRs).The results show that C atom doping can strongly affect the electronic transport properties of the APNR and change it from semiconductor to metal.Meanwhile,obvious negative differential resistance(NDR) behaviors are obtained by tuning the doping position and concentration.In particular,with reducing doping concentration,NDR peak position can enter into m V bias range.These results provide a theoretical support to design the related nanodevice by tuning the doping position and concentration in the APNRs.展开更多
基金This work was financially supported by National Natural Science Foundation of China(Nos.51775046&51875043&52005040)the China Postdoctoral Science Foundation(No.2019M660480)+1 种基金the Beijing Municipal Natural Sci-ence Foundation(JQ20014)The authors would also like to acknowledge support from the Fok Ying-Tong Education Foundation for Young Teachers in the Higher Education Insti-tutions of China(No.151052).
文摘Micro/nanostructured components play an important role in micro-optics and optical engineering,tribology and surface engineering,and biological and biomedical engineering,among other fields.Precision glass molding technology is the most efficient method of manufacturing micro/nanostructured glass components,the premise of which is meld manufacturing with complementary micro/nanostructures.Numerous mold manufacturing methods have been developed to fabricate extremely small and high-quality micro/nanostructures to satisfy the demands of functional micro/nanostructured glass components for various applications.Moreover,the service performance of the mold should also be carefully considered.This paper reviews a variety of technologies for manufacturing micro/nanostructured molds.The authors begin with an introduction of the extreme requirements of mold materials.The following section provides a detailed survey of the existing micro/nanostructured mold manufacturing techniques and their corresponding mold materials,including nonmechanical and mechanical methods.This paper concludes with a detailed discussion of the authors recent research on nickel-phosphorus(Ni-P)mold manufacturing and its service performance.
基金This work was supported by the National Natural Science Foundation of China(Grant No.81027003)the Zhejiang Provincial Science and Technology Major Special Program(No.2010C14006).
文摘Cellular metabolism arouses the changes of substance in extracellular physiological microenvironment,and the metabolic level reflects the physiological state of cells.This paper developed a novel microphysiometer automatic analysis instrument based on multiparameter cell-based biosensors for quick drug analysis.This study included the multiparameter cell-based biosensors,cell culture chamber,drug auto-injection detection and analysis.The analysis instrument was capable of real-time detection for the acidic product and other chemical parameters generated by the cellular metabolism in the micro-volume.Finally,the paper employs human breast cancer cell line MCF-7 and drug experiments to verify the performance of microphysiometer,and study effects of different drugs on cell metabolism.Further,the research explores drug analysis method of the multiparameter microphysiometer.The results showed that the cell-based microphysiometer system provides a utility platform for rapid,long-term and automatic cell physiological environment detection and drug analysis.
基金Project supported by the National Natural Science Foundation of China(Grant No.61605107)Young Eastern Scholar Program at Shanghai Institutions of Higher Learning,China(Grant No.QD2015027)+2 种基金the“Young 1000 Talent Plan”Program of Chinathe Open Program of the State Key Laboratory of Advanced Optical Communication Systems and Networks at Shanghai Jiaotong University,China(Grant No.2017GZKF17)RAEng/The Leverhulme Trust Senior Research Fellowships(Grant No.LTSRF1617/13/57).
文摘We demonstrate a passively harmonic mode-locked(PHML) fiber laser operating at the L-band using carbon nanotubes polyvinyl alcohol(CNTs-PVA) film. Under suitable pump power and an appropriate setting of the polarization controller(PC), the 54^(th) harmonic pulses at the L-band are generated with the side mode suppression ratio(SMSR) better than 44 dB and a repetition frequency of 503.37 MHz. Further increasing the pump power leads to a higher frequency of 550 MHz with compromised stability of 38.5 dB SMSR. To the best of our knowledge, this is the first demonstration on the generation of L-band PHML pulses from an Er-doped fiber laser based on CNTs.
基金supported by the Second Tibetan Plateau Scientific Expedition and Research Program(STEP)(Grant No.2019QZKK0206)the National Natural Science Foundation of China(Grant No.41771395)the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDA20100300)。
文摘The estimation of downward surface shortwave radiation(DSSR)is important for the Earth’s energy budget and climate change studies.This review was organised from the perspectives of satellite sensors,algorithms and future trends,retrospects and summaries of the satellite-based retrieval methods of DSSR that have been developed over the past 10 years.The shortwave radiation reaching the Earth’s surface is affected by both atmospheric and land surface parameters.In recent years,studies have given detailed considerations to the factors which affect DSSR.It is important to improve the retrieval accuracy of cloud microphysical parameters and aerosols and to reduce the uncertainties caused by complex topographies and high-albedo surfaces(such as snow-covered areas)on DSSR estimation.This review classified DSSR retrieval methods into four categories:empirical,parameterisation,look-up table and machine-learning methods,and evaluated their advantages,disadvantages and accuracy.Further efforts are needed to improve the calculation accuracy of atmospheric parameters such as cloud,haze,water vapor and other land surface parameters such as albedo of complex terrain and bright surface,organically combine machine learning and other methods,use the new-generation geostationary satellite and polar orbit satellite data to produce highresolution DSSR products,and promote the application of radiation products in hydrological and climate models.
基金National Key Basic Research Program of China(No.2015CB059900)National Natural Science Foundation of China(Nos.51775046 and 51875043)the Fok Ying-Tong Education Foundation for Young Teachers in the Higher Education Institutions of China(No.151052).
文摘The use of submicron structures for structural coloration of surfaces has broad applications for color filters,projection displays,virtual reality,and anti-counterfeiting.Currently,structural color images lack high resolution due to low manufacturing accuracy.In this study,the axial-feed fly cutting(AFC)method is proposed to fabricate submicron grooves for the diffraction of visible light to create structural color images.We establish the relationship between the color information in the pixels of the original image and the parameters of the array units corresponding to the pixels.An algorithm to determine groove spacing and the tool path is established,and array units with the desired groove spacing are machined to reproduce the structural color images.The submicron grooves fabricated by AFC have high quality and good consistency.Due to the excellent diffraction performance of the machined grooves,images with high saturation and resolution can be reproduced.It is verified that images with various colors can be efficiently fabricated using the proposed method and algorithm.
基金We acknowledge funding from the National Natural Science Foundation of China(Nos.11774079 and 61774059)the Scientific and Technological Innovation Program of Henan Province’s Universities(No.20HASTIT026)+4 种基金the Natural Science Foundation of Henan(No.202300410226)the Natural Science Foundation of Henan Normal University(No.2020PL15)the Henan Overseas Expertise Introduction Center for Discipline Innovation(No.CXJD2019005)the HPCC of HNU.RW acknowledges funding from the US DOE-BES(No.DE-FG02-05ER46237)We thank F.Xue at Tsinghua University,W.Ju and D.Kang at HNUST for helpful discussions.
文摘Two-dimensional(2D)magnetic materials are essential for the development of the next-generation spintronic technologies.Recently,layered van der Waals(vdW)compound MnBi2Te4(MBT)has attracted great interest,and its 2D structure has been reported to host coexisting magnetism and topology.Here,we design several conceptual nanodevices based on MBT monolayer(MBT-ML)and reveal their spin-dependent transport properties by means of the first-principles calculations.The pn-junction diodes and sub-3-nm pin-junction field-effect transistors(FETs)show a strong rectifying effect and a spin filtering effect,with an ideality factor n close to 1 even at a reasonably high temperature.In addition,the pip-and nin-junction FETs give an interesting negative differential resistive(NDR)effect.The gate voltages can tune currents through these FETs in a large range.Furthermore,the MBT-ML has a strong response to light.Our results uncover the multifunctional nature of MBT-ML,pave the road for its applications in diverse next-generation semiconductor spin electric devices.
基金supported by the National Natural Science Foundation of China(NSFC)(No.61605107)the Young Eastern Scholar Program at Shanghai Institutions of Higher Learning(No.QD2015027)+3 种基金the“Young 1000 Talent Plan”Program of Chinasupport from the Ministry of Higher Education,Sultanate of OmanMarie Sklodowask-Curie IEF project(H2020-MSCA-IF-2014_ST,Proposal#:656984)Marie-Curie International Research Staff Exchange Scheme“Tela Sens”project,Research Executive Agency(Grant No.269271,Programme:FP7-PEOPLE-2010-IRSES)
文摘We propose and demonstrate a passively harmonic mode-locked erbium-doped fiber laser(EDFL)using carbon nanotubes polyvinyl alcohol(CNTs-PVA)film.The laser allows generation of the pulses with a repetition rate of 580 MHz,which corresponds to the 22nd harmonics of a 26.3 MHz fundamental repetition rate under 323 mW pump power.A particularly noteworthy feature of the pulses is the super-mode suppression ratio(SMSR),which is over 40 dB,indicating a stable operation.
基金supported by the Center-initiated Research Project of Zheijiang Lab(Grant No.2021MHOALO1)the Startup Grant from Zhejang Lab(Grant No.113010-PI2108)。
文摘Electrophysiological recording is a widely used method to investigate cardiovascular pathology,pharmacology and developmental biology.Microelectrode arrays record the electrical potential of cells in a minimally invasive and highthroughput way.However,commonly used microelectrode arays primarily employ planar microelectrodes and cannot work in applications that require a recording of the intracellular action potential of a single cell.In this study,we proposed a novel measuring method that is able to record the intracellular action potential of a single cardiomyocyte by using a nanowell patterned microelectrode array(NWMEA).The NWMEA consists of five nanoscale wells at the center of each circular planar microelectrode.Biphasic pulse electroporation was applied to the NWMEA to penetrate the cardiomyocyte membrane,and the intracellular action potential was continuously recorded.The intracellular potential recording of cardiomyocytes by the NWMEA measured a potential signal with a higher quality(213.76±25.85%),reduced noise root-mean-square(~33%),and higher signal-to-noise ratio(254.36±12.61%)when compared to those of the extracellular recording.Compared to previously reported nanopillar microelectrodes,the NWMEA could ensure single cell electroporation and acquire high-quality action potential of cardiomyocytes with reduced fabrication processes.This NWMEA-based biosensing system is a promising tool to record the intracellular action potential of a single cell to broaden the usage of microelectrode arrays in electrophysiological investigation.
基金Project supported by the National Natural Science Foundation of China(No.11274096)the University Science and Technology Innovation Team Support Project of Henan Province(No.13IRTSTHN016)+1 种基金the University key Science Research Project of Henan Province(No.16A140043)supported by the High Performance Computing Center of Henan Normal University
文摘By using a combined method of density functional theory and non-equilibrium Green's function formalism,we investigate the electronic transport properties of carbon-doped armchair phosphorene nanoribbons(APNRs).The results show that C atom doping can strongly affect the electronic transport properties of the APNR and change it from semiconductor to metal.Meanwhile,obvious negative differential resistance(NDR) behaviors are obtained by tuning the doping position and concentration.In particular,with reducing doping concentration,NDR peak position can enter into m V bias range.These results provide a theoretical support to design the related nanodevice by tuning the doping position and concentration in the APNRs.