Dendrobium officinale is one of the most precious medicinal plants in China. Its main medicinal ingredients are its secondary metabolites. However,it has the characteristics of limited sources,low active ingredient co...Dendrobium officinale is one of the most precious medicinal plants in China. Its main medicinal ingredients are its secondary metabolites. However,it has the characteristics of limited sources,low active ingredient content and high cost,limiting the use of D. officinale.Studying the network structure and rate-limiting steps of secondary metabolites of medicinal components of D. officinale,analyzing the secondary metabolic synthesis process,mastering the production rules of its medicinal components and carrying out gene cloning or biosynthesis,etc.are of great significance for the rational development and utilization of D. officinale resources. This paper briefly reviews the progress of the research on the secondary metabolites of D. officinale,including the detection and identification of metabolites and the identification and cloning of key metabolic enzymes.展开更多
What is already known about this topic?Lack of social activities is known to negatively impact cognitive functioning and increase risk of cognitive impairment,including dementia,among older adults.What is added by thi...What is already known about this topic?Lack of social activities is known to negatively impact cognitive functioning and increase risk of cognitive impairment,including dementia,among older adults.What is added by this report?Coronavirus disease 2019(COVID-19)stay-at-home orders implemented in the U.S.early during the pandemic were not found to negatively affect cognitive functioning of older adults.What are the implications for public health practice?There may have been no severe,unintended consequences of the COVID-19 stay-at-home orders in terms of their impact on cognitive functioning and risk of dementia among older adults,lending further support to use of such orders.展开更多
基金Supported by National Natural Science Foundation of China(81060028)Key Project of Science and Technology of Guangxi Zhuang Autonomous Region(Gui Ke Zhong 1598005-9)Key Science and Technology Program of Guangxi Zhuang Autonomous Region(Gui Ke Gong 1355005-3-7)
文摘Dendrobium officinale is one of the most precious medicinal plants in China. Its main medicinal ingredients are its secondary metabolites. However,it has the characteristics of limited sources,low active ingredient content and high cost,limiting the use of D. officinale.Studying the network structure and rate-limiting steps of secondary metabolites of medicinal components of D. officinale,analyzing the secondary metabolic synthesis process,mastering the production rules of its medicinal components and carrying out gene cloning or biosynthesis,etc.are of great significance for the rational development and utilization of D. officinale resources. This paper briefly reviews the progress of the research on the secondary metabolites of D. officinale,including the detection and identification of metabolites and the identification and cloning of key metabolic enzymes.
文摘What is already known about this topic?Lack of social activities is known to negatively impact cognitive functioning and increase risk of cognitive impairment,including dementia,among older adults.What is added by this report?Coronavirus disease 2019(COVID-19)stay-at-home orders implemented in the U.S.early during the pandemic were not found to negatively affect cognitive functioning of older adults.What are the implications for public health practice?There may have been no severe,unintended consequences of the COVID-19 stay-at-home orders in terms of their impact on cognitive functioning and risk of dementia among older adults,lending further support to use of such orders.
